Crescent Biopharma (CBIO) EBITDA (2013 - 2026)
Crescent Biopharma (CBIO) reported EBITDA of -$23.3 million for Q1 2026, down 53.7% year-over-year from -$50.3 million in Q1 2025, and up 74.8% quarter-over-quarter from -$92.4 million in Q4 2025.
Crescent Biopharma (CBIO) EBITDA (2013 - 2026) Analysis & Trends
Crescent Biopharma (CBIO) has 14 years of EBITDA data on file, last reported at -$23.3 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$23.3 million, down 53.7% year-over-year; the trailing twelve-month figure through Mar 2026 was -$162.1 million (down 252.31% YoY), and the FY2025 annual result was -$153.9 million, down 761.6% from the prior year.
- EBITDA grew to -$23.3 million in Q1 2026 per CBIO's latest filing, from -$92.4 million in the prior quarter.
- Over five years, EBITDA peaked at -$2.6 million in Q3 2024 and troughed at -$92.4 million in Q4 2025.
- A 5-year average of -$18.0 million and a median of -$11.1 million in 2024 frame the typical range for EBITDA.
- The sharpest annual moves came in 2024 and 2025: EBITDA soared 73.19% in 2024, then sank 835.27% in 2025.
- A 5-year view of EBITDA shows it stood at -$10.6 million in 2022, then gained by 9.71% to -$9.6 million in 2023, then sank by 86.29% to -$17.9 million in 2024, then tumbled by 417.14% to -$92.4 million in 2025, then jumped by 74.8% to -$23.3 million in 2026.
- Business Quant data shows CBIO's EBITDA at -$23.3 million in Q1 2026, -$92.4 million in Q4 2025, and -$24.6 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Crescent Biopharma | 486.92 Mn | 297.76 Mn | - | -23.28 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -23.28 Mn |
| Dec 31, 2025 | -92.40 Mn |
| Sep 30, 2025 | -24.61 Mn |
| Jun 30, 2025 | -21.79 Mn |
| Mar 31, 2025 | -15.15 Mn |
| Dec 31, 2024 | -17.87 Mn |
| Sep 30, 2024 | -2.63 Mn |
| Jun 30, 2024 | -10.36 Mn |
| Mar 31, 2024 | -11.12 Mn |
| Dec 31, 2023 | -9.59 Mn |
| Sep 30, 2023 | -9.81 Mn |
| Jun 30, 2023 | -8.93 Mn |
| Mar 31, 2023 | -10.94 Mn |
| Dec 31, 2022 | -10.62 Mn |
| Sep 30, 2022 | -8.77 Mn |
| Jun 30, 2022 | -13.35 Mn |
| Mar 31, 2022 | -14.66 Mn |
| Dec 31, 2021 | -17.43 Mn |
| Sep 30, 2021 | -17.34 Mn |
| Jun 30, 2021 | -14.40 Mn |