Candel Therapeutics (CADL) Operating Income (2020 - 2025)

Candel Therapeutics (CADL) reported Operating Income of -$15.8 million for Q4 2025, down 93.49% on a YoY basis from -$242.0 million in Q4 2024, and down 19.27% sequentially from -$13.2 million in Q3 2025.

Candel Therapeutics (CADL) Operating Income (2020 - 2025) Analysis & Trends

Candel Therapeutics (CADL) has 6 years of Operating Income data on file, last reported at -$15.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Income fell 93.49% year-over-year to -$15.8 million; the trailing twelve-month figure through Dec 2025 stood at -$48.3 million (down 44.63% YoY), and the FY2025 full-year result was -$48.3 million, down 44.63% from the prior year.
  • Operating Income retreated to -$15.8 million in Q4 2025, from -$13.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$4.7 million in Q1 2021 to a low of -$15.8 million in Q4 2025.
  • A 5-year average of -$9.0 million and a median of -$8.8 million in 2022 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income slumped 192.07% in 2021 and advanced 21.1% in 2024, its largest moves.
  • Tracing CADL's Operating Income over 5 years: stood at -$7.7 million in 2021, then slipped by 4.66% to -$8.1 million in 2022, then fell by 27.37% to -$10.3 million in 2023, then climbed by 21.1% to -$8.1 million in 2024, then plunged by 93.49% to -$15.8 million in 2025.
  • Business Quant data shows CADL's Operating Income at -$15.8 million in Q4 2025, -$13.2 million in Q3 2025, and -$11.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Candel Therapeutics 504.70 Mn 504.70 Mn - -15.75 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -15.75 Mn
Sep 30, 2025 -13.21 Mn
Jun 30, 2025 -11.18 Mn
Mar 31, 2025 -8.13 Mn
Dec 31, 2024 -8.14 Mn
Sep 30, 2024 -8.76 Mn
Jun 30, 2024 -8.57 Mn
Mar 31, 2024 -7.90 Mn
Dec 31, 2023 -10.32 Mn
Sep 30, 2023 -8.86 Mn
Jun 30, 2023 -9.58 Mn
Mar 31, 2023 -9.63 Mn
Dec 31, 2022 -8.10 Mn
Sep 30, 2022 -8.88 Mn
Jun 30, 2022 -8.75 Mn
Mar 31, 2022 -8.99 Mn
Dec 31, 2021 -7.74 Mn
Sep 30, 2021 -8.03 Mn
Jun 30, 2021 -5.30 Mn
Mar 31, 2021 -4.66 Mn