Candel Therapeutics (CADL) EBITDA (2020 - 2025)

Candel Therapeutics recorded quarterly EBITDA of -$15.8 million in Q4 2025, down 19.27% quarter-over-quarter from -$13.2 million in Q3 2025, and down 93.49% year-over-year from -$242.0 million in Q4 2024.

Candel Therapeutics' EBITDA history runs 6 years deep, the most recent figure standing at -$15.8 million for Q4 2025.

  • In Q4 2025, EBITDA fell 93.49% year-over-year to -$15.8 million; the TTM figure through Dec 2025 stood at -$48.3 million (down 44.63% YoY), while the FY2025 annual figure was -$48.3 million, down 44.63% from the prior year.
  • EBITDA came in at -$15.8 million for Q4 2025 at Candel Therapeutics, down from -$13.2 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $1.6 million in Q4 2021 to a low of -$17.1 million in Q2 2021.
  • A 5-year average of -$9.6 million and a median of -$8.9 million in 2022 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA jumped 115.16% in 2021 and plunged 607.58% in 2022, its largest moves.
  • Candel Therapeutics' EBITDA stood at $1.6 million in 2021, then slumped by 607.58% to -$8.1 million in 2022, then decreased by 27.37% to -$10.3 million in 2023, then increased by 21.1% to -$8.1 million in 2024, then slumped by 93.49% to -$15.8 million in 2025.
  • According to Business Quant data, EBITDA over the past three periods registered -$15.8 million, -$13.2 million, and -$11.2 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Candel Therapeutics 449.62 Mn 449.62 Mn - -15.75 Mn

Historic Data

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DateValue
Dec 31, 2025 -15.75 Mn
Sep 30, 2025 -13.21 Mn
Jun 30, 2025 -11.18 Mn
Mar 31, 2025 -8.13 Mn
Dec 31, 2024 -8.14 Mn
Sep 30, 2024 -8.76 Mn
Jun 30, 2024 -8.57 Mn
Mar 31, 2024 -7.90 Mn
Dec 31, 2023 -10.32 Mn
Sep 30, 2023 -8.86 Mn
Jun 30, 2023 -9.58 Mn
Mar 31, 2023 -9.63 Mn
Dec 31, 2022 -8.10 Mn
Sep 30, 2022 -8.88 Mn
Jun 30, 2022 -8.75 Mn
Mar 31, 2022 -8.99 Mn
Dec 31, 2021 1.60 Mn
Sep 30, 2021 -16.16 Mn
Jun 30, 2021 -17.08 Mn
Mar 31, 2021 -4.66 Mn
Dec 31, 2020 -10.53 Mn
Sep 30, 2020 -2.56 Mn
Jun 30, 2020 -2.57 Mn