Cabaletta Bio (CABA) EBITDA (2018 - 2025)

Cabaletta Bio's (CABA) quarterly EBITDA came in at -$42.6 million in Q4 2025, down 26.12% year-on-year from -$57.7 million in Q4 2024, and up 8.54% quarter-over-quarter from -$46.6 million in Q3 2025.

Cabaletta Bio (CABA) EBITDA (2018 - 2025) Analysis & Trends

Cabaletta Bio's EBITDA history runs 8 years deep, the most recent figure standing at -$42.6 million for Q4 2025.

  • On a quarterly basis, EBITDA fell 26.12% year-over-year to -$42.6 million in Q4 2025; TTM through Dec 2025 was -$172.2 million, a 37.64% decrease from a year earlier, with the FY2025 full-year figure at -$172.2 million, down 37.64% from the prior year.
  • EBITDA grew to -$42.6 million in Q4 2025 per CABA's latest filing, from -$46.6 million in the prior quarter.
  • Across five years, EBITDA topped out at -$9.7 million in Q1 2021 and bottomed at -$46.6 million in Q3 2025.
  • The 5-year median for EBITDA is -$17.8 million (2023), against an average of -$23.6 million.
  • Across the five-year window, EBITDA slipped 1.86% in 2022 and plunged 90.55% in 2024, its largest moves.
  • Year by year, EBITDA stood at -$13.9 million in 2021, then fell by 17.34% to -$16.3 million in 2022, then plunged by 41.98% to -$23.1 million in 2023, then slumped by 45.96% to -$33.8 million in 2024, then declined by 26.12% to -$42.6 million in 2025.
  • Per Business Quant, the three latest CABA EBITDA figures stand at -$42.6 million (Q4 2025), -$46.6 million (Q3 2025), and -$45.9 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Cabaletta Bio 182.04 Mn 182.04 Mn - -42.61 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -42.61 Mn
Sep 30, 2025 -46.59 Mn
Jun 30, 2025 -45.91 Mn
Mar 31, 2025 -37.14 Mn
Dec 31, 2024 -33.79 Mn
Sep 30, 2024 -33.05 Mn
Jun 30, 2024 -30.28 Mn
Mar 31, 2024 -28.03 Mn
Dec 31, 2023 -23.15 Mn
Sep 30, 2023 -18.67 Mn
Jun 30, 2023 -15.89 Mn
Mar 31, 2023 -16.96 Mn
Dec 31, 2022 -16.30 Mn
Sep 30, 2022 -11.78 Mn
Jun 30, 2022 -13.06 Mn
Mar 31, 2022 -13.00 Mn
Dec 31, 2021 -13.89 Mn
Sep 30, 2021 -11.56 Mn
Jun 30, 2021 -11.15 Mn
Mar 31, 2021 -9.71 Mn