Cabaletta Bio (CABA) EBITDA (2018 - 2025)
Cabaletta Bio (CABA) recorded quarterly EBITDA of -$41.9 million in Q4 2025, up 6.53% quarter-over-quarter from -$44.8 million in Q3 2025, and down 28.63% on a YoY basis from -$58.7 million in Q4 2024.
Cabaletta Bio (CABA) EBITDA (2018 - 2025) Analysis & Trends
Cabaletta Bio's EBITDA history runs 8 years deep, the most recent figure standing at -$41.9 million for Q4 2025.
- In Q4 2025, EBITDA fell 28.63% year-over-year to -$41.9 million; the TTM figure through Dec 2025 stood at -$167.8 million (down 44.8% YoY), while the FY2025 annual figure was -$167.8 million, down 44.8% from the prior year.
- EBITDA was -$41.9 million for Q4 2025 at Cabaletta Bio, up from -$44.8 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$9.7 million in Q1 2021 to a low of -$45.1 million in Q2 2025.
- Historically, EBITDA has averaged -$22.5 million across 5 years, with a median of -$16.1 million in 2023.
- The sharpest annual moves came in 2022 and 2024: EBITDA climbed 1.51% in 2022, then tumbled 90.43% in 2024.
- A 5-year view of EBITDA shows it stood at -$13.9 million in 2021, then declined by 11.87% to -$15.5 million in 2022, then plunged by 33.8% to -$20.8 million in 2023, then slumped by 56.83% to -$32.6 million in 2024, then declined by 28.63% to -$41.9 million in 2025.
- The last three EBITDA figures came in at -$41.9 million (Q4 2025), -$44.8 million (Q3 2025), and -$45.1 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Cabaletta Bio | 151.84 Mn | 18.24 Mn | - | -41.92 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -41.92 Mn |
| Sep 30, 2025 | -44.84 Mn |
| Jun 30, 2025 | -45.13 Mn |
| Mar 31, 2025 | -35.94 Mn |
| Dec 31, 2024 | -32.59 Mn |
| Sep 30, 2024 | -30.60 Mn |
| Jun 30, 2024 | -27.59 Mn |
| Mar 31, 2024 | -25.12 Mn |
| Dec 31, 2023 | -20.78 Mn |
| Sep 30, 2023 | -16.47 Mn |
| Jun 30, 2023 | -14.49 Mn |
| Mar 31, 2023 | -15.81 Mn |
| Dec 31, 2022 | -15.53 Mn |
| Sep 30, 2022 | -11.39 Mn |
| Jun 30, 2022 | -13.01 Mn |
| Mar 31, 2022 | -13.10 Mn |
| Dec 31, 2021 | -13.88 Mn |
| Sep 30, 2021 | -11.56 Mn |
| Jun 30, 2021 | -11.14 Mn |
| Mar 31, 2021 | -9.71 Mn |