Cabaletta Bio (CABA) EBITDA (2018 - 2025)

Cabaletta Bio (CABA) recorded quarterly EBITDA of -$41.9 million in Q4 2025, up 6.53% quarter-over-quarter from -$44.8 million in Q3 2025, and down 28.63% on a YoY basis from -$58.7 million in Q4 2024.

Cabaletta Bio (CABA) EBITDA (2018 - 2025) Analysis & Trends

Cabaletta Bio's EBITDA history runs 8 years deep, the most recent figure standing at -$41.9 million for Q4 2025.

  • In Q4 2025, EBITDA fell 28.63% year-over-year to -$41.9 million; the TTM figure through Dec 2025 stood at -$167.8 million (down 44.8% YoY), while the FY2025 annual figure was -$167.8 million, down 44.8% from the prior year.
  • EBITDA was -$41.9 million for Q4 2025 at Cabaletta Bio, up from -$44.8 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$9.7 million in Q1 2021 to a low of -$45.1 million in Q2 2025.
  • Historically, EBITDA has averaged -$22.5 million across 5 years, with a median of -$16.1 million in 2023.
  • The sharpest annual moves came in 2022 and 2024: EBITDA climbed 1.51% in 2022, then tumbled 90.43% in 2024.
  • A 5-year view of EBITDA shows it stood at -$13.9 million in 2021, then declined by 11.87% to -$15.5 million in 2022, then plunged by 33.8% to -$20.8 million in 2023, then slumped by 56.83% to -$32.6 million in 2024, then declined by 28.63% to -$41.9 million in 2025.
  • The last three EBITDA figures came in at -$41.9 million (Q4 2025), -$44.8 million (Q3 2025), and -$45.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Cabaletta Bio 151.84 Mn 18.24 Mn - -41.92 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -41.92 Mn
Sep 30, 2025 -44.84 Mn
Jun 30, 2025 -45.13 Mn
Mar 31, 2025 -35.94 Mn
Dec 31, 2024 -32.59 Mn
Sep 30, 2024 -30.60 Mn
Jun 30, 2024 -27.59 Mn
Mar 31, 2024 -25.12 Mn
Dec 31, 2023 -20.78 Mn
Sep 30, 2023 -16.47 Mn
Jun 30, 2023 -14.49 Mn
Mar 31, 2023 -15.81 Mn
Dec 31, 2022 -15.53 Mn
Sep 30, 2022 -11.39 Mn
Jun 30, 2022 -13.01 Mn
Mar 31, 2022 -13.10 Mn
Dec 31, 2021 -13.88 Mn
Sep 30, 2021 -11.56 Mn
Jun 30, 2021 -11.14 Mn
Mar 31, 2021 -9.71 Mn