BioNTech SE (BNTX) Operating Income (2018 - 2025)
BioNTech SE's (BNTX) quarterly Operating Income came in at -$375.8 million in Q4 2025, down 336.63% year-on-year from $158.8 million in Q4 2024, and down 585.32% quarter-over-quarter from -$54.8 million in Q3 2025.
BioNTech SE (BNTX) Operating Income (2018 - 2025) Analysis & Trends
BioNTech SE has disclosed Operating Income across 8 years of filings, most recently posting -$375.8 million for Q4 2025.
- Operating Income for Q4 2025 came in at -$375.8 million, down 336.63% year-over-year; the trailing twelve-month figure through Dec 2025 was -$1.6 billion (down 9.74% YoY), and the FY2025 annual result was -$1.6 billion, down 13.02% from the prior year.
- Operating Income came in at -$375.8 million for Q4 2025 at BioNTech SE, down from -$54.8 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $5.6 billion in Q3 2021 to a low of -$1.0 billion in Q2 2024.
- The 5-year median for Operating Income is $362.5 million (2024), against an average of $1.5 billion.
- Across the five-year window, Operating Income jumped 5574.02% in 2021 and tumbled 575.48% in 2025, its largest moves.
- BioNTech SE's Operating Income stood at $5.4 billion in 2021, then plunged by 37.51% to $3.4 billion in 2022, then tumbled by 83.15% to $566.2 million in 2023, then slumped by 71.95% to $158.8 million in 2024, then tumbled by 336.63% to -$375.8 million in 2025.
- The last three Operating Income figures came in at -$375.8 million (Q4 2025), -$54.8 million (Q3 2025), and -$567.2 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | BioNTech SE | 27.38 Bn | 10.07 Bn | 668.28 Mn | -375.75 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -375.75 Mn |
| Sep 30, 2025 | -54.83 Mn |
| Jun 30, 2025 | -567.22 Mn |
| Mar 31, 2025 | -561.81 Mn |
| Dec 31, 2024 | 158.79 Mn |
| Sep 30, 2024 | 11.53 Mn |
| Jun 30, 2024 | -1.04 Bn |
| Mar 31, 2024 | -551.00 Mn |
| Dec 31, 2023 | 566.16 Mn |
| Sep 30, 2023 | 79.58 Mn |
| Jun 30, 2023 | -613.39 Mn |
| Mar 31, 2023 | 702.39 Mn |
| Dec 31, 2022 | 3.36 Bn |
| Sep 30, 2022 | 2.41 Bn |
| Jun 30, 2022 | 2.36 Bn |
| Mar 31, 2022 | 5.33 Bn |
| Dec 31, 2021 | 5.38 Bn |
| Sep 30, 2021 | 5.57 Bn |
| Jun 30, 2021 | 5.06 Bn |
| Mar 31, 2021 | 2.01 Bn |