BioNTech SE (BNTX) Operating Income (2018 - 2025)
BioNTech SE (BNTX) reported Operating Income of -$375.8 million for Q4 2025, down 336.63% on a YoY basis from $158.8 million in Q4 2024, and down 585.32% sequentially from -$54.8 million in Q3 2025.
BioNTech SE (BNTX) Operating Income (2018 - 2025) Analysis & Trends
BioNTech SE (BNTX) has 8 years of Operating Income data on file, last reported at -$375.8 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Income fell 336.63% year-over-year to -$375.8 million; the trailing twelve-month figure through Dec 2025 stood at -$1.6 billion (down 9.74% YoY), and the FY2025 full-year result was -$1.6 billion, down 13.02% from the prior year.
- Operating Income declined to -$375.8 million in Q4 2025, from -$54.8 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $6.1 billion in Q1 2022 to a low of -$1.0 billion in Q2 2024.
- A 5-year average of $1.7 billion and a median of $362.5 million in 2024 frame the typical range for Operating Income.
- Across the five-year window, Operating Income jumped 5574.02% in 2021 and sank 575.48% in 2025, its largest moves.
- Tracing BNTX's Operating Income over 5 years: stood at $5.4 billion in 2021, then sank by 37.51% to $3.4 billion in 2022, then plunged by 83.15% to $566.2 million in 2023, then tumbled by 71.95% to $158.8 million in 2024, then plunged by 336.63% to -$375.8 million in 2025.
- Business Quant data shows BNTX's Operating Income at -$375.8 million in Q4 2025, -$54.8 million in Q3 2025, and -$567.2 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | BioNTech SE | 22.13 Bn | 22.13 Bn | 668.28 Mn | -375.75 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -375.75 Mn |
| Sep 30, 2025 | -54.83 Mn |
| Jun 30, 2025 | -567.22 Mn |
| Mar 31, 2025 | -561.81 Mn |
| Dec 31, 2024 | 158.79 Mn |
| Sep 30, 2024 | 11.53 Mn |
| Jun 30, 2024 | -1.04 Bn |
| Mar 31, 2024 | -551.00 Mn |
| Dec 31, 2023 | 566.16 Mn |
| Sep 30, 2023 | 79.58 Mn |
| Jun 30, 2023 | -613.39 Mn |
| Mar 31, 2023 | 702.39 Mn |
| Dec 31, 2022 | 3.36 Bn |
| Sep 30, 2022 | 3.22 Bn |
| Jun 30, 2022 | 5.07 Bn |
| Mar 31, 2022 | 6.12 Bn |
| Dec 31, 2021 | 5.38 Bn |
| Sep 30, 2021 | 5.57 Bn |
| Jun 30, 2021 | 5.06 Bn |
| Mar 31, 2021 | 2.01 Bn |