Bicycle Therapeutics (BCYC) Operating Income (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Operating Income of -$65.5 million for Q1 2026, down 165.02% on a QoQ basis from -$24.7 million in Q4 2025, and up 6.73% year-over-year from -$61.4 million in Q1 2025.
Bicycle Therapeutics (BCYC) Operating Income (2018 - 2026) Analysis & Trends
Bicycle Therapeutics' Operating Income history runs 9 years deep, the most recent figure standing at -$65.5 million for Q1 2026.
- Quarterly Operating Income rose 6.73% year-over-year to -$65.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$242.3 million (up 2.42% YoY) and the FY2025 annual result came in at -$247.1 million, down 17.72% from the prior year.
- Operating Income was -$65.5 million for Q1 2026 at Bicycle Therapeutics, down from -$24.7 million in the prior quarter.
- Across five years, Operating Income topped out at -$24.7 million in Q4 2025 and bottomed at -$86.6 million in Q2 2025.
- A 5-year average of -$48.8 million and a median of -$46.6 million in 2024 frame the typical range for Operating Income.
- Peak annual rise in Operating Income reached 63.48% in 2025, while the deepest fall reached 121.35% in 2025.
- Bicycle Therapeutics' Operating Income stood at -$32.2 million in 2022, then sank by 68.37% to -$54.2 million in 2023, then slipped by 24.76% to -$67.7 million in 2024, then jumped by 63.48% to -$24.7 million in 2025, then slumped by 165.02% to -$65.5 million in 2026.
- Business Quant data shows BCYC's Operating Income at -$65.5 million in Q1 2026, -$24.7 million in Q4 2025, and -$65.6 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Bicycle Therapeutics | 289.88 Mn | 289.88 Mn | - | -65.48 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -65.48 Mn |
| Dec 31, 2025 | -24.71 Mn |
| Sep 30, 2025 | -65.55 Mn |
| Jun 30, 2025 | -86.60 Mn |
| Mar 31, 2025 | -70.20 Mn |
| Dec 31, 2024 | -67.66 Mn |
| Sep 30, 2024 | -63.85 Mn |
| Jun 30, 2024 | -46.65 Mn |
| Mar 31, 2024 | -31.72 Mn |
| Dec 31, 2023 | -54.24 Mn |
| Sep 30, 2023 | -50.80 Mn |
| Jun 30, 2023 | -43.11 Mn |
| Mar 31, 2023 | -41.80 Mn |
| Dec 31, 2022 | -32.21 Mn |
| Sep 30, 2022 | -29.76 Mn |
| Jun 30, 2022 | -27.30 Mn |
| Mar 31, 2022 | -27.38 Mn |
| Dec 31, 2021 | -18.02 Mn |
| Sep 30, 2021 | -14.29 Mn |
| Jun 30, 2021 | -17.28 Mn |