Bicycle Therapeutics (BCYC) EBT (2018 - 2026)

Bicycle Therapeutics (BCYC) posted EBT of -$60.7 million for Q1 2026, down 129.36% on a QoQ basis from $206.6 million in Q4 2025, and up 1.92% year-over-year from -$59.5 million in Q1 2025.

Bicycle Therapeutics (BCYC) EBT (2018 - 2026) Analysis & Trends

Bicycle Therapeutics' EBT history runs 9 years deep, the most recent figure standing at -$60.7 million for Q1 2026.

  • Quarterly EBT rose 1.92% year-over-year to -$60.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $7.8 million (up 103.75% YoY) and the FY2025 annual result came in at $6.6 million, up 103.83% from the prior year.
  • EBT was -$60.7 million for Q1 2026 at Bicycle Therapeutics, down from $206.6 million in the prior quarter.
  • Across five years, EBT topped out at $206.6 million in Q4 2025 and bottomed at -$79.2 million in Q2 2025.
  • A 5-year average of -$20.0 million and a median of -$39.7 million in 2024 frame the typical range for EBT.
  • Annual changes were most pronounced in 2023 — EBT surged 513.79% — and 2024, when it plunged 139.45%.
  • Bicycle Therapeutics' EBT stood at -$32.4 million in 2022, then jumped by 513.79% to $134.2 million in 2023, then plunged by 139.45% to -$52.9 million in 2024, then surged by 490.22% to $206.6 million in 2025, then slumped by 129.36% to -$60.7 million in 2026.
  • Business Quant data shows BCYC's EBT at -$60.7 million in Q1 2026, $206.6 million in Q4 2025, and -$58.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Bicycle Therapeutics 272.11 Mn 272.11 Mn - -60.65 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -60.65 Mn
Dec 31, 2025 206.57 Mn
Sep 30, 2025 -58.90 Mn
Jun 30, 2025 -79.18 Mn
Mar 31, 2025 -61.84 Mn
Dec 31, 2024 -52.94 Mn
Sep 30, 2024 -54.25 Mn
Jun 30, 2024 -39.70 Mn
Mar 31, 2024 -26.91 Mn
Dec 31, 2023 134.20 Mn
Sep 30, 2023 -47.63 Mn
Jun 30, 2023 -43.12 Mn
Mar 31, 2023 -39.68 Mn
Dec 31, 2022 -32.43 Mn
Sep 30, 2022 -28.59 Mn
Jun 30, 2022 -27.28 Mn
Mar 31, 2022 -27.98 Mn
Dec 31, 2021 -18.79 Mn
Sep 30, 2021 -15.09 Mn
Jun 30, 2021 -18.07 Mn