Avalo Therapeutics AVTX
NASDAQ AVTX
$8.51 +1.35 (+18.85%)
At close: Nov 11, 2026 · 4:00 PM EST

Avalo Therapeutics (AVTX) Return on Sales [ROS] (2016 - 2026)

Updated

Avalo Therapeutics' Return on Sales [ROS] came in at -33461.02% for Q4 2025, down 26528.20 percentage points from -6932.81% a year earlier and down 18383.01 percentage points from the prior quarter.

Analysis

Avalo Therapeutics (AVTX) Return on Sales [ROS] (2016 - 2026) Analysis & Trends

For FY2025, Avalo Therapeutics' Return on Sales [ROS] was -123601.69%, down 108066.09 percentage points from FY2024.

  • Return on Sales [ROS] has declined in each of the last three years, with a five-year change of -122514.32 percentage points (FY2020 to FY2025).
  • Going back by year, Return on Sales [ROS] was -15535.60% in FY2024 (-14114.03 pp), -1421.57% in FY2023 (-1214.16 pp), -207.41% in FY2022 (+1314.15 pp) and -1521.56% in FY2021 (-434.19 pp).
  • The Q4 2025 figure represents the lowest quarterly Return on Sales [ROS] in data going back to Q3 2016.
  • The fastest year-over-year change in Return on Sales [ROS] over five years came in Q4 2022 (a gain of 7214.00 percentage points), and the weakest in Q4 2025 (a drop of 26528.20 percentage points).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 34.46%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 24.35%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn 36.01%
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 30.74%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 29.12%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 35.79%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn 41.71%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 32.98%
10 Avalo Therapeutics 386.09 Mn -587.48 Mn - -550.65%
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 -550.65%
Jun 30, 2026 -1,141.51%
Mar 31, 2026 -2,602.86%
Dec 31, 2025 -33,461.02%
Sep 30, 2025 -2,728.52%
Jun 30, 2025 -1,760.80%
Mar 31, 2025 -1,277.79%
Dec 31, 2024 -6,932.81%
Sep 30, 2024 -5,165.06%
Jun 30, 2024 -6,660.47%
Mar 31, 2024 -3,539.66%
Dec 31, 2023 -1,341.16%
Sep 30, 2023 -1,588.98%
Jun 30, 2023 -1,111.98%
Mar 31, 2023 -1,850.95%
Dec 31, 2022 -988.28%
Sep 30, 2022 27.39%
Jun 30, 2022 -1,145.01%
Mar 31, 2022 -1,777.75%
Dec 31, 2021 -8,202.28%
API Access

Avalo Therapeutics Return on Sales [ROS] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=AVTX&period=max&api_key=YOUR_API_KEY