Autolus Therapeutics (AUTL) Return on Sales (2017 - 2025)

Autolus Therapeutics posted quarterly Return on Sales of 0.04% for Q4 2025, up 948.0% year-on-year from 0.0% in Q4 2024, and little changed on a QoQ basis from 0.04% in Q3 2025.

Autolus Therapeutics (AUTL) has 7 years of Return on Sales data on file, last reported at 0.04% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Sales rose 948.0% year-over-year to 0.04%; the trailing twelve-month figure through Dec 2025 stood at 0.04% (up 18.0% YoY), and the FY2025 full-year result was 0.04%, up 18.0% from the prior year.
  • Return on Sales for Q4 2025 stood at 0.04%, roughly flat from 0.04% in the prior quarter.
  • Across five years, Return on Sales topped out at 569.85% in Q2 2022 and bottomed at 1896.65% in Q3 2021.
  • The 5-year median for Return on Sales is 0.29% (2024), against an average of 67.64%.
  • The widest annual swing landed in 2021, when Return on Sales sank 189544 bps; it then surged 189791 bps in 2022.
  • A 5-year view of Return on Sales shows it stood at 0.06% in 2021, then sank by 15836 bps to 8.97% in 2022, then jumped by 86 bps to 1.23% in 2023, then tumbled by 676 bps to 9.52% in 2024, then soared by 100 bps to 0.04% in 2025.
  • The last three Return on Sales figures came in at 0.04% (Q4 2025), 0.04% (Q3 2025), and 0.02% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 0.00%
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 0.00%
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 0.00%
8 Evaxion A 65.12 Bn 65.10 Bn - 0.00%
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 0.00%
10 Autolus Therapeutics - - -1.04 Mn -0.04%

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -0.04%
Sep 30, 2025 -0.04%
Jun 30, 2025 -0.02%
Mar 31, 2025 -0.08%
Dec 31, 2024 -9.52%
Sep 30, 2024 -0.27%
Jun 30, 2024 -0.22%
Mar 31, 2024 -0.05%
Dec 31, 2023 -1.23%
Sep 30, 2023 -1.13%
Jun 30, 2023 -1.20%
Mar 31, 2023 -0.31%
Dec 31, 2022 -8.97%
Sep 30, 2022 1.26%
Jun 30, 2022 569.85%
Mar 31, 2022 -2.23%
Dec 31, 2021 0.06%
Sep 30, 2021 -1,896.65%
Jun 30, 2021 -0.30%
Mar 31, 2021 -1.66%
Dec 31, 2020 -0.14%
Sep 30, 2020 -1.21%
Jun 30, 2020 -1.57%
Mar 31, 2020 -1.10%
Dec 31, 2017 -0.33%