Autolus Therapeutics (AUTL) Profit After Tax (2017 - 2025)

Autolus Therapeutics posted quarterly Profit After Tax of -$90.3 million for Q4 2025, down 227.74% year-on-year from $70.7 million in Q4 2024, and down 14.2% on a QoQ basis from -$79.1 million in Q3 2025.

Autolus Therapeutics (AUTL) has 9 years of Profit After Tax data on file, last reported at -$90.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Profit After Tax fell 227.74% year-over-year to -$90.3 million; the trailing twelve-month figure through Dec 2025 stood at -$287.5 million (down 30.29% YoY), and the FY2025 full-year result was -$287.5 million, down 30.3% from the prior year.
  • Profit After Tax for Q4 2025 stood at -$90.3 million, down from -$79.1 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $42.8 million in Q3 2022 and bottomed at -$242.5 million in Q4 2021.
  • The 5-year median for Profit After Tax is -$45.7 million (2023), against an average of -$38.4 million.
  • The widest annual swing landed in 2022, when Profit After Tax jumped 88.89%; it then plunged 232.35% in 2024.
  • A 5-year view of Profit After Tax shows it stood at -$242.5 million in 2021, then surged by 88.89% to -$26.9 million in 2022, then slumped by 186.47% to -$77.2 million in 2023, then surged by 64.28% to -$27.6 million in 2024, then tumbled by 227.74% to -$90.3 million in 2025.
  • The last three Profit After Tax figures came in at -$90.3 million (Q4 2025), -$79.1 million (Q3 2025), and -$47.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -2.99 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.03 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 727.20 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -3.63 Mn
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 205.99 Mn
10 Autolus Therapeutics - - -1.04 Mn -90.33 Mn

Historic Data

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DateValue
Dec 31, 2025 -90.33 Mn
Sep 30, 2025 -79.10 Mn
Jun 30, 2025 -47.90 Mn
Mar 31, 2025 -70.16 Mn
Dec 31, 2024 -27.56 Mn
Sep 30, 2024 -82.10 Mn
Jun 30, 2024 -58.30 Mn
Mar 31, 2024 -52.69 Mn
Dec 31, 2023 -77.17 Mn
Sep 30, 2023 -45.80 Mn
Jun 30, 2023 -45.60 Mn
Mar 31, 2023 39.81 Mn
Dec 31, 2022 -26.94 Mn
Sep 30, 2022 42.77 Mn
Jun 30, 2022 -42.06 Mn
Mar 31, 2022 37.06 Mn
Dec 31, 2021 -242.53 Mn
Sep 30, 2021 33.99 Mn
Jun 30, 2021 33.17 Mn
Mar 31, 2021 33.27 Mn
Dec 31, 2020 -241.33 Mn
Sep 30, 2020 37.32 Mn
Jun 30, 2020 32.05 Mn
Mar 31, 2020 29.87 Mn
Jun 30, 2019 55.66 Mn
Mar 31, 2019 27.18 Mn
Dec 31, 2018 7.36 Mn
Sep 30, 2018 12.86 Mn
Jun 30, 2018 24.37 Mn
Mar 31, 2018 -19.65 Mn
Dec 31, 2017 -7.52 Mn