Autolus Therapeutics (AUTL) EBT (2017 - 2025)

Autolus Therapeutics (AUTL) posted quarterly EBT of -$91.5 million for Q4 2025, down 250.04% year-on-year from $61.0 million in Q4 2024, and down 16.45% on a QoQ basis from -$78.6 million in Q3 2025.

Autolus Therapeutics (AUTL) EBT (2017 - 2025) Analysis & Trends

Autolus Therapeutics (AUTL) has reported EBT for 9 consecutive years, with -$91.5 million the latest figure, recorded in Q4 2025.

  • Quarterly EBT fell 250.04% year-over-year to -$91.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$285.6 million (down 30.31% YoY) and the FY2025 annual result came in at -$285.6 million, down 30.31% from the prior year.
  • EBT eased to -$91.5 million in Q4 2025 per AUTL's latest filing, from -$78.6 million in the prior quarter.
  • Over the last five years, EBT for AUTL reached as high as -$7.4 million in Q4 2022 and fell as low as -$91.5 million in Q4 2025.
  • A 5-year average of -$49.2 million and a median of -$44.1 million in 2022 frame the typical range for EBT.
  • Annual changes were most pronounced in 2022 — EBT soared 69.23% — and 2023, when it slumped 939.1%.
  • Year by year, EBT stood at -$24.1 million in 2021, then surged by 69.23% to -$7.4 million in 2022, then sank by 939.1% to -$77.2 million in 2023, then jumped by 66.13% to -$26.1 million in 2024, then slumped by 250.04% to -$91.5 million in 2025.
  • According to Business Quant data, EBT over the past three periods registered -$91.5 million, -$78.6 million, and -$47.5 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.97 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 259.22 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.49 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 541.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Autolus Therapeutics 404.53 Mn 103.82 Mn -1.04 Mn -91.52 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -91.52 Mn
Sep 30, 2025 -78.59 Mn
Jun 30, 2025 -47.52 Mn
Mar 31, 2025 -67.94 Mn
Dec 31, 2024 -26.14 Mn
Sep 30, 2024 -82.07 Mn
Jun 30, 2024 -58.22 Mn
Mar 31, 2024 -52.70 Mn
Dec 31, 2023 -77.20 Mn
Sep 30, 2023 -45.87 Mn
Jun 30, 2023 -45.51 Mn
Mar 31, 2023 -39.83 Mn
Dec 31, 2022 -7.43 Mn
Sep 30, 2022 -42.77 Mn
Jun 30, 2022 -42.12 Mn
Mar 31, 2022 -37.09 Mn
Dec 31, 2021 -24.14 Mn
Sep 30, 2021 -39.38 Mn
Jun 30, 2021 -39.53 Mn
Mar 31, 2021 -38.99 Mn