Autolus Therapeutics (AUTL) EBITDA (2017 - 2025)
Autolus Therapeutics posted quarterly EBITDA of -$90.8 million for Q4 2025, down 62.43% year-on-year from -$241.6 million in Q4 2024, and down 6.91% on a QoQ basis from -$84.9 million in Q3 2025.
Autolus Therapeutics (AUTL) has 9 years of EBITDA data on file, last reported at -$90.8 million in Q4 2025.
- For the quarter ending Q4 2025, EBITDA fell 62.43% year-over-year to -$90.8 million; the trailing twelve-month figure through Dec 2025 stood at -$263.7 million (down 19.41% YoY), and the FY2025 full-year result was -$263.7 million, down 19.41% from the prior year.
- EBITDA for Q4 2025 stood at -$90.8 million, down from -$84.9 million in the prior quarter.
- Across five years, EBITDA topped out at $40.5 million in Q3 2021 and bottomed at -$248.9 million in Q4 2021.
- The 5-year median for EBITDA is -$53.9 million (2024), against an average of -$50.4 million.
- The widest annual swing landed in 2022, when EBITDA surged 92.65%; it then sank 295.78% in 2023.
- A 5-year view of EBITDA shows it stood at -$248.9 million in 2021, then soared by 92.65% to -$18.3 million in 2022, then tumbled by 295.78% to -$72.4 million in 2023, then rose by 22.78% to -$55.9 million in 2024, then slumped by 62.43% to -$90.8 million in 2025.
- The last three EBITDA figures came in at -$90.8 million (Q4 2025), -$84.9 million (Q3 2025), and -$28.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 661.60 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Autolus Therapeutics | - | - | -1.04 Mn | -90.77 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -90.77 Mn |
| Sep 30, 2025 | -84.90 Mn |
| Jun 30, 2025 | -28.95 Mn |
| Mar 31, 2025 | -59.09 Mn |
| Dec 31, 2024 | -55.88 Mn |
| Sep 30, 2024 | -55.08 Mn |
| Jun 30, 2024 | -57.25 Mn |
| Mar 31, 2024 | -52.63 Mn |
| Dec 31, 2023 | -72.37 Mn |
| Sep 30, 2023 | -51.69 Mn |
| Jun 30, 2023 | -40.25 Mn |
| Mar 31, 2023 | -34.17 Mn |
| Dec 31, 2022 | -18.29 Mn |
| Sep 30, 2022 | -56.82 Mn |
| Jun 30, 2022 | -59.54 Mn |
| Mar 31, 2022 | -44.52 Mn |
| Dec 31, 2021 | -248.88 Mn |
| Sep 30, 2021 | 40.45 Mn |
| Jun 30, 2021 | 31.63 Mn |
| Mar 31, 2021 | 31.99 Mn |
| Dec 31, 2020 | -247.10 Mn |
| Sep 30, 2020 | 26.40 Mn |
| Jun 30, 2020 | 33.86 Mn |
| Mar 31, 2020 | 47.57 Mn |
| Jun 30, 2019 | 37.35 Mn |
| Mar 31, 2019 | 22.13 Mn |
| Sep 30, 2018 | 13.83 Mn |
| Jun 30, 2018 | 18.86 Mn |
| Mar 31, 2018 | -18.18 Mn |
| Dec 31, 2017 | -8.92 Mn |