Autolus Therapeutics (AUTL) EBITDA (2017 - 2025)
Autolus Therapeutics (AUTL) posted EBITDA of -$72.5 million for Q4 2025, down 1.18% on a QoQ basis from -$71.6 million in Q3 2025, and up 4.48% year-over-year from -$69.4 million in Q4 2024.
Autolus Therapeutics (AUTL) EBITDA (2017 - 2025) Analysis & Trends
Autolus Therapeutics' EBITDA history runs 6 years deep, the most recent figure standing at -$72.5 million for Q4 2025.
- Quarterly EBITDA rose 4.48% year-over-year to -$72.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$270.5 million (down 12.06% YoY) and the FY2025 annual result came in at -$270.5 million, down 12.06% from the prior year.
- EBITDA was -$72.5 million for Q4 2025 at Autolus Therapeutics, down from -$71.6 million in the prior quarter.
- Across five years, EBITDA topped out at -$11.6 million in Q4 2022 and bottomed at -$75.9 million in Q4 2024.
- A 4-year average of -$51.0 million and a median of -$48.8 million in 2023 frame the typical range for EBITDA.
- Annual changes were most pronounced in 2023 — EBITDA sank 357.26% — and 2025, when it increased 4.48%.
- Autolus Therapeutics' EBITDA stood at -$11.6 million in 2022, then plunged by 357.26% to -$53.3 million in 2023, then tumbled by 42.41% to -$75.9 million in 2024, then gained by 4.48% to -$72.5 million in 2025.
- Business Quant data shows AUTL's EBITDA at -$72.5 million in Q4 2025, -$71.6 million in Q3 2025, and -$61.2 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Autolus Therapeutics | 384.57 Mn | 83.86 Mn | -1.04 Mn | -72.47 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -72.47 Mn |
| Sep 30, 2025 | -71.62 Mn |
| Jun 30, 2025 | -61.22 Mn |
| Mar 31, 2025 | -65.24 Mn |
| Dec 31, 2024 | -75.86 Mn |
| Sep 30, 2024 | -67.88 Mn |
| Jun 30, 2024 | -58.93 Mn |
| Mar 31, 2024 | -38.76 Mn |
| Dec 31, 2023 | -53.27 Mn |
| Sep 30, 2023 | -42.91 Mn |
| Jun 30, 2023 | -44.38 Mn |
| Mar 31, 2023 | -39.15 Mn |
| Dec 31, 2022 | -11.65 Mn |
| Sep 30, 2022 | -37.35 Mn |
| Jun 30, 2022 | -39.06 Mn |
| Mar 31, 2022 | -36.19 Mn |
| Sep 30, 2018 | -57.53 Mn |
| Dec 31, 2017 | -8.92 Mn |