Annovis Bio (ANVS) Return on Capital Employed [ROCE] (2020 - 2026)
Annovis Bio (ANVS) posted Return on Capital Employed [ROCE] of -387.55% for Q2 2026, down 276.24 percentage points from -111.31% a year earlier but up 317.99 percentage points from the prior quarter.
Powered by 
Analysis
Annovis Bio (ANVS) Return on Capital Employed [ROCE] (2020 - 2026) Analysis & Trends
For FY2025, Annovis Bio's Return on Capital Employed [ROCE] came in at -214.16%, up 112.01 percentage points from FY2024.
- Annual Return on Capital Employed [ROCE] shows a five-year change of -49.79 percentage points (FY2020 to FY2025).
- In prior years, Annovis Bio's Return on Capital Employed [ROCE] was -326.17% in FY2024 (-87.08 pp), -239.09% in FY2023 (-162.51 pp), -76.58% in FY2022 (-19.69 pp) and -56.89% in FY2021 (+107.48 pp).
- Quarterly Return on Capital Employed [ROCE] has run from a low of -1722.66% in Q2 2024 to a high of -22.18% in Q3 2021 over five years.
- On a year-over-year basis, Return on Capital Employed [ROCE] increased in five of the last eight quarters, with an average year-over-year change of +298.40 percentage points.
- The strongest year-over-year quarter for Return on Capital Employed [ROCE] in the past five years was Q2 2025, with a gain of 1611.35 percentage points; the weakest was Q2 2024, with a drop of 1568.80 percentage points.
- According to Business Quant data, Return on Capital Employed [ROCE] for the three prior quarters was -705.54% (Q1 2026), -191.73% (Q4 2025) and -171.58% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,082.65 Bn | 1,051.23 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 623.68 Bn | 542.21 Bn | 17.26 Bn | 17.83% |
| 3 | AbbVie | 459.43 Bn | 432.59 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 354.80 Bn | 309.23 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 269.16 Bn | 225.03 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 244.40 Bn | 217.97 Bn | 12.86 Bn | 9.54% |
| 7 | Amgen | 220.17 Bn | 175.57 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 183.05 Bn | 157.16 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 160.27 Bn | 107.22 Bn | 10.94 Bn | 11.86% |
| 10 | Annovis Bio | 49.42 Mn | 49.42 Mn | - | -387.55% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -387.55% |
| Mar 31, 2026 | -705.54% |
| Dec 31, 2025 | -191.73% |
| Sep 30, 2025 | -171.58% |
| Jun 30, 2025 | -111.31% |
| Mar 31, 2025 | -141.30% |
| Dec 31, 2024 | -260.17% |
| Sep 30, 2024 | -704.79% |
| Jun 30, 2024 | -1,722.66% |
| Mar 31, 2024 | -1,035.26% |
| Dec 31, 2023 | -758.48% |
| Sep 30, 2023 | -327.24% |
| Jun 30, 2023 | -153.86% |
| Mar 31, 2023 | -119.13% |
| Dec 31, 2022 | -88.36% |
| Sep 30, 2022 | -65.61% |
| Jun 30, 2022 | -49.10% |
| Mar 31, 2022 | -37.94% |
| Dec 31, 2021 | -32.08% |
| Sep 30, 2021 | -22.18% |
API Access
Annovis Bio Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=ANVS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "ANVS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=ANVS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();