Annovis Bio, Inc. (ANVS) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

17,401,709Shares Outstanding

169,008Shares held by institutions

$402,239Value of institutional holdings

24.74%Institutional ownership %

148.50%Shares Changed QoQ

50No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 50 institutional investors hold a position in Annovis Bio, Inc. (NYSE:ANVS).

The collective stake of institutional investors in Annovis Bio moved to 24.7% in December 2025, a shift up from the 11.5% reported for September 2025.
Quarterly data indicates a 148.50% shift in institutional share volume, and the annual owner count reflects an increase of 21.95%.
Among the 50 institutional holders of Annovis Bio, 34 added to their stakes while 3 trimmed their positions and 13 held steady.
Collectively, institutional investors increased their stake in Annovis Bio to 4.30Mn shares as of December 2025, a change that is up by 2.57Mn shares quarter on quarter and up 2.73Mn shares year over year.
The top institutional stake in Annovis Bio as of December 31, 2025 belongs to VANGUARD GROUP INC, which owns 923.20K shares, or 5.31% of the company.
Among the most significant buyers of Annovis Bio during December 2025 were MARSHALL WACE, LLP (725.86K), TWO SIGMA INVESTMENTS, LP (551.84K), JANE STREET GROUP, LLC (404.76K), VANGUARD GROUP INC (185.20K), D.A. DAVIDSON & CO. (160.78K).
Leading sellers of Annovis Bio stock in December 2025 included Wilmington Savings Fund Society, FSB (9.39K), Greenwich Wealth Management LLC (5.00K), NORTHERN TRUST CORP (198).
The top 10 institutional holders of Annovis Bio for the quarter ending December 2025 included VANGUARD GROUP INC (923.20K), MARSHALL WACE, LLP (725.86K), TWO SIGMA INVESTMENTS, LP (551.84K), JANE STREET GROUP, LLC (404.76K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (303.29K), GEODE CAPITAL MANAGEMENT, LLC (222.13K), D.A. DAVIDSON & CO. (160.78K), BlackRock, Inc. (139.53K), NORTHERN TRUST CORP (120.86K), Merit Financial Group, LLC (81.32K).

50 Institutional Holders

169,008 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	923,201	185,198	25.09%	$3,194,275.00
MARSHALL WACE, LLP	31 Dec, 2025	725,862	725,862	0.00%	$2,511,482.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	551,837	551,837	0.00%	$1,909,356.00
JANE STREET GROUP, LLC	31 Dec, 2025	404,757	404,757	0.00%	$1,400,459.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	303,287	84,866	38.85%	$1,049,373.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	222,132	37,978	20.62%	$768,711.00
D.A. DAVIDSON & CO.	31 Dec, 2025	160,779	160,779	0.00%	$556,295.00
BlackRock, Inc.	31 Dec, 2025	139,533	58,858	72.96%	$482,784.00
NORTHERN TRUST CORP	31 Dec, 2025	120,862	-198	-0.16%	$418,182.00
Merit Financial Group, LLC	31 Dec, 2025	81,316	0	0.00%	$281,353.00
STATE STREET CORP	31 Dec, 2025	74,035	35,600	92.62%	$256,161.00
GROUP ONE TRADING LLC	31 Dec, 2025	69,126	34,499	99.63%	$239,176.00
OMERS ADMINISTRATION Corp	31 Dec, 2025	62,100	62,100	0.00%	$214,866.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	45,221	45,221	0.00%	$156,465.00
Greenwich Wealth Management LLC	31 Dec, 2025	42,400	-5,000	-10.55%	$147.00
Wescott Financial Advisory Group, LLC	31 Dec, 2025	41,607	0	0.00%	$143,960.00
UBS Group AG	31 Dec, 2025	30,643	30,010	4,740.92%	$106,025.00
Sherry Group, Inc.	31 Dec, 2025	27,270	27,270	0.00%	$94,354.00
Dakota Wealth Management	31 Dec, 2025	26,200	26,200	0.00%	$90,652.00
BRIDGEWAY CAPITAL MANAGEMENT, LLC	31 Dec, 2025	24,400	5,000	25.77%	$84,424.00

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