AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026)
AN2 Therapeutics (ANTX) reported Return on Capital Employed of 53.68% for Q1 2026, up 21.3% quarter-over-quarter from 68.21% in Q4 2025.
AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026) Analysis & Trends
AN2 Therapeutics (ANTX) has 5 years of Return on Capital Employed data on file, last reported at 53.68% in Q1 2026.
- Return on Capital Employed for Q1 2026 came in at 53.68%, changed N/A year-over-year; the trailing twelve-month figure through Mar 2026 was 53.68% (changed N/A YoY), and the FY2025 annual result was 55.8%, down 181.0% from the prior year.
- Return on Capital Employed advanced to 53.68% in Q1 2026 per ANTX's latest filing, from 68.21% in the prior quarter.
- Over five years, Return on Capital Employed peaked at 28.03% in Q2 2022 and troughed at 72.0% in Q3 2024.
- A 5-year average of 52.59% and a median of 55.22% in 2023 frame the typical range for Return on Capital Employed.
- The sharpest annual moves came in 2023 and 2025: Return on Capital Employed tumbled 3982 bps in 2023, then sank 112 bps in 2025.
- A 5-year view of Return on Capital Employed shows it stood at 42.65% in 2022, then retreated by 23 bps to 52.66% in 2023, then declined by 27 bps to 67.09% in 2024, then decreased by 2 bps to 68.21% in 2025, then grew by 21 bps to 53.68% in 2026.
- Business Quant data shows ANTX's Return on Capital Employed at 53.68% in Q1 2026, 68.21% in Q4 2025, and 67.09% in Q4 2024.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | 450.31% |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | 51.73% |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -107.40% |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -50.43% |
| 10 | AN2 Therapeutics | 161.95 Mn | 161.95 Mn | - | -53.68% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -53.68% |
| Dec 31, 2025 | -68.21% |
| Dec 31, 2024 | -67.09% |
| Sep 30, 2024 | -72.00% |
| Dec 31, 2023 | -52.66% |
| Sep 30, 2023 | -56.75% |
| Jun 30, 2023 | -67.85% |
| Mar 31, 2023 | -57.35% |
| Dec 31, 2022 | -42.65% |
| Sep 30, 2022 | -33.80% |
| Jun 30, 2022 | -28.03% |
| Mar 31, 2022 | -30.98% |