AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026)

AN2 Therapeutics (ANTX) reported Return on Capital Employed of 53.68% for Q1 2026, up 21.3% quarter-over-quarter from 68.21% in Q4 2025.

AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026) Analysis & Trends

AN2 Therapeutics (ANTX) has 5 years of Return on Capital Employed data on file, last reported at 53.68% in Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 53.68%, changed N/A year-over-year; the trailing twelve-month figure through Mar 2026 was 53.68% (changed N/A YoY), and the FY2025 annual result was 55.8%, down 181.0% from the prior year.
  • Return on Capital Employed advanced to 53.68% in Q1 2026 per ANTX's latest filing, from 68.21% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 28.03% in Q2 2022 and troughed at 72.0% in Q3 2024.
  • A 5-year average of 52.59% and a median of 55.22% in 2023 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2023 and 2025: Return on Capital Employed tumbled 3982 bps in 2023, then sank 112 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 42.65% in 2022, then retreated by 23 bps to 52.66% in 2023, then declined by 27 bps to 67.09% in 2024, then decreased by 2 bps to 68.21% in 2025, then grew by 21 bps to 53.68% in 2026.
  • Business Quant data shows ANTX's Return on Capital Employed at 53.68% in Q1 2026, 68.21% in Q4 2025, and 67.09% in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - 450.31%
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 51.73%
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -107.40%
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 21.10%
9 Abivax 90.15 Bn 90.15 Bn - -50.43%
10 AN2 Therapeutics 161.95 Mn 161.95 Mn - -53.68%

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.68%
Dec 31, 2025 -68.21%
Dec 31, 2024 -67.09%
Sep 30, 2024 -72.00%
Dec 31, 2023 -52.66%
Sep 30, 2023 -56.75%
Jun 30, 2023 -67.85%
Mar 31, 2023 -57.35%
Dec 31, 2022 -42.65%
Sep 30, 2022 -33.80%
Jun 30, 2022 -28.03%
Mar 31, 2022 -30.98%