AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026)

AN2 Therapeutics' (ANTX) quarterly Return on Capital Employed came in at 53.68% in Q1 2026, up 21.3% on a QoQ basis from 68.21% in Q4 2025.

AN2 Therapeutics (ANTX) Return on Capital Employed (2022 - 2026) Analysis & Trends

AN2 Therapeutics (ANTX) has 5 years of Return on Capital Employed data on file, last reported at 53.68% in Q1 2026.

  • On a quarterly basis, Return on Capital Employed changed N/A year-over-year to 53.68% in Q1 2026; TTM through Mar 2026 was 53.68%, a N/A change from a year earlier, with the FY2025 full-year figure at 55.8%, down 181.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 53.68%, up from 68.21% in the prior quarter.
  • Over the last five years, Return on Capital Employed for ANTX reached as high as 28.03% in Q2 2022 and fell as low as 72.0% in Q3 2024.
  • Historically, Return on Capital Employed has averaged 52.59% across 5 years, with a median of 55.22% in 2023.
  • Across the five-year window, Return on Capital Employed sank 3982 bps in 2023 and tumbled 112 bps in 2025, its largest moves.
  • Year by year, Return on Capital Employed stood at 42.65% in 2022, then dropped by 23 bps to 52.66% in 2023, then decreased by 27 bps to 67.09% in 2024, then declined by 2 bps to 68.21% in 2025, then gained by 21 bps to 53.68% in 2026.
  • Per Business Quant data, the three most recent Return on Capital Employed figures were 53.68% in Q1 2026, 68.21% in Q4 2025, and 67.09% in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 AN2 Therapeutics 167.57 Mn 167.57 Mn - -53.68%

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.68%
Dec 31, 2025 -68.21%
Dec 31, 2024 -67.09%
Sep 30, 2024 -72.00%
Dec 31, 2023 -52.66%
Sep 30, 2023 -56.75%
Jun 30, 2023 -67.85%
Mar 31, 2023 -57.35%
Dec 31, 2022 -42.65%
Sep 30, 2022 -33.80%
Jun 30, 2022 -28.03%
Mar 31, 2022 -30.98%