Annexon (ANNX) Operating Income (2019 - 2026)

Annexon's Operating Income history runs 8 years deep, the most recent figure standing at -$46.1 million for Q1 2026.

• On a quarterly basis, Operating Income rose 19.78% year-over-year to -$46.1 million in Q1 2026; TTM through Mar 2026 was -$205.1 million, a 12.11% decrease from a year earlier, with the FY2025 full-year figure at -$216.4 million, down 40.46% from the prior year.
• Operating Income improved to -$46.1 million in Q1 2026 per ANNX's latest filing, from -$50.3 million in the prior quarter.
• Across five years, Operating Income topped out at -$28.6 million in Q1 2024 and bottomed at -$57.4 million in Q1 2025.
• The 5-year median for Operating Income is -$37.7 million (2023), against an average of -$41.5 million.
• Across the five-year window, Operating Income soared 30.72% in 2024 and plunged 100.91% in 2025, its largest moves.
• Year by year, Operating Income stood at -$36.7 million in 2022, then rose by 18.22% to -$30.0 million in 2023, then tumbled by 74.88% to -$52.5 million in 2024, then climbed by 4.23% to -$50.3 million in 2025, then grew by 8.37% to -$46.1 million in 2026.
• Per Business Quant, the three latest ANNX Operating Income figures stand at -$46.1 million (Q1 2026), -$50.3 million (Q4 2025), and -$57.0 million (Q3 2025).