Annexon (ANNX) Operating Income (2019 - 2026)

Annexon's Operating Income history runs 8 years deep, the most recent figure standing at -$46.1 million for Q1 2026.

• In Q1 2026, Operating Income rose 19.78% year-over-year to -$46.1 million; the TTM figure through Mar 2026 stood at -$205.1 million (down 12.11% YoY), while the FY2025 annual figure was -$216.4 million, down 40.46% from the prior year.
• Operating Income for Q1 2026 stood at -$46.1 million, up from -$50.3 million in the prior quarter.
• The five-year high for Operating Income was -$28.6 million in Q1 2024, with the low at -$57.4 million in Q1 2025.
• The 5-year median for Operating Income is -$37.7 million (2023), against an average of -$41.5 million.
• The sharpest annual moves came in 2024 and 2025: Operating Income soared 30.72% in 2024, then tumbled 100.91% in 2025.
• Annexon's Operating Income stood at -$36.7 million in 2022, then increased by 18.22% to -$30.0 million in 2023, then plunged by 74.88% to -$52.5 million in 2024, then advanced by 4.23% to -$50.3 million in 2025, then climbed by 8.37% to -$46.1 million in 2026.
• Business Quant data shows ANNX's Operating Income at -$46.1 million in Q1 2026, -$50.3 million in Q4 2025, and -$57.0 million in Q3 2025.