Annexon ANNX
NASDAQ ANNX
$4.84 +0.00 (+0.00%)
As of: Sep 4, 2026 · 12:47 PM EDT

Annexon (ANNX) EBITDA (2019 - 2026)

Annexon (ANNX) posted quarterly EBITDA of -$46.1 million for Q1 2026, up 19.78% year-over-year from -$38.4 million in Q1 2025, and up 8.37% quarter-over-quarter from -$50.3 million in Q4 2025.

Analysis

Annexon (ANNX) EBITDA (2019 - 2026) Analysis & Trends

Annexon's EBITDA history runs 8 years deep, the most recent figure standing at -$46.1 million for Q1 2026.

  • In Q1 2026, EBITDA rose 19.78% year-over-year to -$46.1 million; the TTM figure through Mar 2026 stood at -$205.1 million (down 12.11% YoY), while the FY2025 annual figure was -$216.4 million, down 40.46% from the prior year.
  • EBITDA for Q1 2026 stood at -$46.1 million, up from -$50.3 million in the prior quarter.
  • The five-year high for EBITDA was -$28.6 million in Q1 2024, with the low at -$57.4 million in Q1 2025.
  • The 5-year median for EBITDA is -$37.7 million (2023), against an average of -$41.5 million.
  • The sharpest annual moves came in 2024 and 2025: EBITDA soared 30.72% in 2024, then tumbled 100.91% in 2025.
  • Annexon's EBITDA stood at -$36.7 million in 2022, then increased by 18.22% to -$30.0 million in 2023, then plunged by 74.88% to -$52.5 million in 2024, then advanced by 4.23% to -$50.3 million in 2025, then climbed by 8.37% to -$46.1 million in 2026.
  • Business Quant data shows ANNX's EBITDA at -$46.1 million in Q1 2026, -$50.3 million in Q4 2025, and -$57.0 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 139.76 Bn 131.91 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.72 Bn 77.72 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.56 Bn 58.38 Bn 1.37 Bn 493.00 Mn
4 Moderna 57.87 Bn 52.73 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.06 Bn 44.06 Bn - -505.13 Mn
6 BeOne Medicines 40.08 Bn 34.98 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.20 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.54 Bn 27.70 Bn - 133.12 Mn
9 Insmed 27.49 Bn 26.33 Bn 358.27 Mn -1.55 Mn
10 Annexon 972.45 Mn 972.45 Mn - -56.69 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -56.69 Mn
Mar 31, 2026 -45.55 Mn
Dec 31, 2025 -49.66 Mn
Sep 30, 2025 -56.52 Mn
Jun 30, 2025 -51.19 Mn
Mar 31, 2025 -56.91 Mn
Dec 31, 2024 -51.88 Mn
Sep 30, 2024 -38.94 Mn
Jun 30, 2024 -33.08 Mn
Mar 31, 2024 -28.07 Mn
Dec 31, 2023 -30.01 Mn
Sep 30, 2023 -34.78 Mn
Jun 30, 2023 -37.69 Mn
Mar 31, 2023 -41.24 Mn
Dec 31, 2022 -36.70 Mn
Sep 30, 2022 -36.07 Mn
Jun 30, 2022 -37.41 Mn
Mar 31, 2022 -35.43 Mn
Dec 31, 2021 -37.46 Mn
Sep 30, 2021 -35.68 Mn