Annexon (ANNX) EBIT (2019 - 2026)
Annexon (ANNX) posted quarterly EBIT of -$46.1 million for Q1 2026, up 19.78% year-over-year from -$38.4 million in Q1 2025, and up 8.37% quarter-over-quarter from -$50.3 million in Q4 2025.
Annexon (ANNX) EBIT (2019 - 2026) Analysis & Trends
Annexon's EBIT history runs 8 years deep, the most recent figure standing at -$46.1 million for Q1 2026.
- In Q1 2026, EBIT rose 19.78% year-over-year to -$46.1 million; the TTM figure through Mar 2026 stood at -$205.1 million (down 12.11% YoY), while the FY2025 annual figure was -$216.4 million, down 40.46% from the prior year.
- EBIT for Q1 2026 stood at -$46.1 million, up from -$50.3 million in the prior quarter.
- The five-year high for EBIT was -$28.6 million in Q1 2024, with the low at -$57.4 million in Q1 2025.
- The 5-year median for EBIT is -$37.7 million (2023), against an average of -$41.5 million.
- The sharpest annual moves came in 2024 and 2025: EBIT soared 30.72% in 2024, then tumbled 100.91% in 2025.
- Annexon's EBIT stood at -$36.7 million in 2022, then increased by 18.22% to -$30.0 million in 2023, then plunged by 74.88% to -$52.5 million in 2024, then advanced by 4.23% to -$50.3 million in 2025, then climbed by 8.37% to -$46.1 million in 2026.
- Business Quant data shows ANNX's EBIT at -$46.1 million in Q1 2026, -$50.3 million in Q4 2025, and -$57.0 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 493.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 325.05 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -3,158.03 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 133.12 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 231.44 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Annexon | 1.00 Bn | 1.00 Bn | - | -57.23 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -57.23 Mn |
| Mar 31, 2026 | -46.05 Mn |
| Dec 31, 2025 | -50.26 Mn |
| Sep 30, 2025 | -57.02 Mn |
| Jun 30, 2025 | -51.73 Mn |
| Mar 31, 2025 | -57.41 Mn |
| Dec 31, 2024 | -52.48 Mn |
| Sep 30, 2024 | -39.44 Mn |
| Jun 30, 2024 | -33.58 Mn |
| Mar 31, 2024 | -28.57 Mn |
| Dec 31, 2023 | -30.01 Mn |
| Sep 30, 2023 | -34.78 Mn |
| Jun 30, 2023 | -37.69 Mn |
| Mar 31, 2023 | -41.24 Mn |
| Dec 31, 2022 | -36.70 Mn |
| Sep 30, 2022 | -36.07 Mn |
| Jun 30, 2022 | -37.41 Mn |
| Mar 31, 2022 | -35.43 Mn |
| Dec 31, 2021 | -37.46 Mn |
| Sep 30, 2021 | -35.68 Mn |