Amylyx Pharmaceuticals (AMLX) Return on Sales (2021 - 2025)

Amylyx Pharmaceuticals has reported Return on Sales over the past 5 years, most recently at 239.74% for Q3 2025.

  • Quarterly results put Return on Sales at 239.74% for Q3 2025, down 6497.0% from a year ago — trailing twelve months through Sep 2025 was 239.74% (down 23820.0% YoY), and the annual figure for FY2024 was 0.0%, down 14.0%.
  • Return on Sales for Q3 2025 was 239.74% at Amylyx Pharmaceuticals, up from 518.9% in the prior quarter.
  • Over the last five years, Return on Sales for AMLX hit a ceiling of 103.24% in Q1 2025 and a floor of 538.08% in Q2 2022.
  • Median Return on Sales over the past 5 years was 81.2% (2021), compared with a mean of 162.52%.
  • Biggest five-year swings in Return on Sales: surged 53831bps in 2023 and later crashed -44783bps in 2025.
  • Amylyx Pharmaceuticals' Return on Sales stood at 308.44% in 2021, then surged by 102bps to 5.87% in 2022, then crashed by -98bps to 0.11% in 2023, then plummeted by -368546bps to 415.43% in 2024, then surged by 42bps to 239.74% in 2025.
  • The last three reported values for Return on Sales were 239.74% (Q3 2025), 518.9% (Q2 2025), and 103.24% (Q1 2025) per Business Quant data.