Amylyx Pharmaceuticals (AMLX) Return on Invested Capital (2022 - 2025)

Amylyx Pharmaceuticals' Return on Invested Capital history runs 4 years deep, the most recent figure standing at 0.0% for Q4 2025.

• In Q4 2025, Return on Invested Capital changed 0.0% year-over-year to 0.0%; the TTM figure through Dec 2025 stood at 0.0% (changed 0.0% YoY), while the FY2025 annual figure was 0.0%, changed 0.0% from the prior year.
• Return on Invested Capital was 0.0% for Q4 2025 at Amylyx Pharmaceuticals, down from 0.0% in the prior quarter.
• In the past five years, Return on Invested Capital ranged from a high of 0.0% in Q3 2025 to a low of 0.01% in Q3 2024.
• Historically, Return on Invested Capital has averaged 0.0% across 4 years, with a median of 0.0% in 2023.
• The sharpest annual moves came in 2024 and 2025: Return on Invested Capital slipped 1 bps in 2024, then gained 2 bps in 2025.
• A 4-year view of Return on Invested Capital shows it stood at 0.01% in 2022, then jumped by 110 bps to 0.0% in 2023, then sank by 526 bps to 0.0% in 2024, then jumped by 62 bps to 0.0% in 2025.
• The last three Return on Invested Capital figures came in at 0.0% (Q4 2025), 0.0% (Q3 2025), and 0.0% (Q2 2025), per Business Quant data.