Alnylam Pharmaceuticals (ALNY) Return on Equity [ROE] (2010 - 2026)
Alnylam Pharmaceuticals' Return on Equity [ROE] was 63.78% in Q2 2026, up 122.02 percentage points from -58.24% a year earlier and up 6.07 percentage points from the prior quarter.
Powered by 
Analysis
Alnylam Pharmaceuticals (ALNY) Return on Equity [ROE] (2010 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Alnylam Pharmaceuticals came in at 73.28%.
- Return on Equity [ROE] shows a five-year change of +143.21 percentage points (FY2020 to FY2025).
- In earlier years, Return on Equity [ROE] was -526.14% in FY2022 (-419.84 pp) and -106.31% in FY2021 (-36.38 pp).
- The Q2 2026 figure marks the highest quarterly Return on Equity [ROE] in data going back to Q3 2010.
- Compared with a year earlier, Return on Equity [ROE] has increased for four straight quarters, with an average year-over-year change of +798.25 percentage points over the last four quarters.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q3 2025 (a gain of 2299.03 percentage points); the worst was Q3 2022 (a drop of 2076.86 percentage points).
- Per Business Quant data, ALNY's Return on Equity [ROE] in the three quarters before Q2 2026 was 57.71% (Q1 2026), 61.33% (Q4 2025) and 30.01% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 653.54 Bn | 572.07 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 467.01 Bn | 440.17 Bn | 12.70 Bn | - |
| 3 | Merck | 367.16 Bn | 321.59 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 277.56 Bn | 233.43 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 258.23 Bn | 231.79 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 224.14 Bn | 179.54 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 187.30 Bn | 161.42 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 163.47 Bn | 110.41 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 133.31 Bn | 105.31 Bn | 2.84 Bn | 22.24% |
| 10 | Alnylam Pharmaceuticals | 34.23 Bn | 22.28 Bn | 992.69 Mn | 63.78% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 63.78% |
| Mar 31, 2026 | 57.71% |
| Dec 31, 2025 | 61.33% |
| Sep 30, 2025 | 30.01% |
| Jun 30, 2025 | -58.24% |
| Mar 31, 2025 | -93.45% |
| Dec 31, 2024 | -559.44% |
| Sep 30, 2024 | -2,269.02% |
| Sep 30, 2022 | -2,181.00% |
| Jun 30, 2022 | -339.82% |
| Mar 31, 2022 | -180.49% |
| Dec 31, 2021 | -126.90% |
| Sep 30, 2021 | -104.14% |
| Jun 30, 2021 | -99.65% |
| Mar 31, 2021 | -90.23% |
| Dec 31, 2020 | -76.93% |
| Sep 30, 2020 | -68.15% |
| Jun 30, 2020 | -61.55% |
| Mar 31, 2020 | -63.58% |
| Dec 31, 2019 | -58.19% |
API Access
Alnylam Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ALNY&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();