AC Immune (ACIU) Return on Equity [ROE] (2016 - 2026)
AC Immune (ACIU) reported Return on Equity [ROE] of -128.20% for the quarter ended Jun 30, 2026, down 68.49 percentage points from -59.72% a year earlier but up 42.50 percentage points from the prior quarter.
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Analysis
AC Immune (ACIU) Return on Equity [ROE] (2016 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, AC Immune posted Return on Equity [ROE] of -93.50%, down 55.73 percentage points from the prior year.
- Return on Equity [ROE] has a five-year change of -67.30 percentage points (years ended Dec 2020 to Dec 2025).
- By year, Return on Equity [ROE] came in at -37.77% in the year ended Dec 31, 2024 (-3.85 pp), -33.92% in the year ended Dec 31, 2023 (+0.49 pp), -34.42% in the year ended Dec 31, 2022 (-1.38 pp) and -33.03% in the year ended Dec 31, 2021 (-6.84 pp).
- Five-year quarterly Return on Equity [ROE] spans a low of -170.70% in the quarter ended Mar 31, 2026 and a high of -31.13% in the quarter ended Sep 30, 2024.
- Year over year, Return on Equity [ROE] has now declined in each of the last seven quarters, with an average year-over-year change of -44.70 percentage points over the last eight quarters.
- The high point for year-over-year Return on Equity [ROE] in five years was the quarter ended Sep 30, 2024 (a gain of 18.84 percentage points); the low point was the quarter ended Mar 31, 2026 (a drop of 121.03 percentage points).
- Per Business Quant data, the three quarters before the quarter ended Jun 30, 2026 came in at -170.70% (quarter ended Mar 31, 2026), -126.01% (quarter ended Dec 31, 2025) and -100.53% (quarter ended Sep 30, 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | AC Immune | 266.56 Mn | 266.56 Mn | - | -128.20% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -128.20% |
| Mar 31, 2026 | -170.70% |
| Dec 31, 2025 | -126.01% |
| Sep 30, 2025 | -100.53% |
| Jun 30, 2025 | -59.72% |
| Mar 31, 2025 | -49.67% |
| Dec 31, 2024 | -41.17% |
| Sep 30, 2024 | -31.13% |
| Jun 30, 2024 | -45.08% |
| Mar 31, 2024 | -35.56% |
| Dec 31, 2023 | -37.20% |
| Sep 30, 2023 | -49.97% |
| Jun 30, 2023 | -44.40% |
| Mar 31, 2023 | -42.72% |
| Dec 31, 2022 | -39.90% |
| Sep 30, 2022 | -38.23% |
| Jun 30, 2022 | -36.71% |
| Mar 31, 2022 | -33.81% |
| Dec 31, 2021 | -35.74% |
| Sep 30, 2021 | -38.89% |
API Access
AC Immune Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ACIU&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ACIU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ACIU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();