Growth Metrics

AC Immune (ACIU) Retained Earnings (2015 - 2025)

AC Immune (ACIU) reported Retained Earnings of -$549.3 million for Q4 2025, down 30.67% year-over-year from -$792.3 million in Q4 2024, and down 4.68% on a QoQ basis from -$524.7 million in Q3 2025.

AC Immune (ACIU) has 11 years of Retained Earnings data on file, last reported at -$549.3 million in Q4 2025.

  • Quarterly Retained Earnings fell 30.67% year-over-year to -$549.3 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$549.3 million (down 30.67% YoY) and the FY2025 annual result came in at -$529.5 million, down 25.97% from the prior year.
  • Retained Earnings retreated to -$549.3 million in Q4 2025 per ACIU's latest filing, from -$524.7 million in the prior quarter.
  • Across five years, Retained Earnings topped out at -$236.9 million in Q1 2022 and bottomed at -$356.5 billion in Q4 2023.
  • The 5-year median for Retained Earnings is -$411.5 million (2024), against an average of -$56.3 billion.
  • The widest annual swing landed in 2021, when Retained Earnings sank 193052.78%; it then jumped 99.88% in 2024.
  • Tracing ACIU's Retained Earnings over 5 years: stood at -$217.9 billion in 2021, then surged by 99.87% to -$274.1 million in 2022, then slumped by 129971.79% to -$356.5 billion in 2023, then jumped by 99.88% to -$420.4 million in 2024, then slumped by 30.67% to -$549.3 million in 2025.
  • Per Business Quant, the three latest ACIU Retained Earnings figures stand at -$549.3 million (Q4 2025), -$524.7 million (Q3 2025), and -$491.6 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 AC Immune 325.88 Mn 211.53 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -549.29 Mn
Sep 30, 2025 -524.73 Mn
Jun 30, 2025 -491.56 Mn
Mar 31, 2025 -429.56 Mn
Dec 31, 2024 -420.35 Mn
Sep 30, 2024 -402.75 Mn
Jun 30, 2024 -392.12 Mn
Mar 31, 2024 -381.01 Mn
Dec 31, 2023 -356.47 Bn
Sep 30, 2023 -351.52 Mn
Jun 30, 2023 -329.27 Mn
Mar 31, 2023 -302.84 Mn
Dec 31, 2022 -274.05 Mn
Sep 30, 2022 -251.61 Mn
Jun 30, 2022 -238.98 Mn
Mar 31, 2022 -236.91 Mn
Dec 31, 2021 -217.92 Bn
Sep 30, 2021 -197.86 Bn
Jun 30, 2021 -183.22 Bn
Mar 31, 2021 -164.55 Bn
Dec 31, 2020 -146.95 Mn
Sep 30, 2020 -124.97 Mn
Jun 30, 2020 -100.89 Mn
Mar 31, 2020 -85.19 Mn
Dec 31, 2019 -76.31 Mn
Sep 30, 2019 -56.36 Mn
Jun 30, 2019 -73,970.33
Mar 31, 2019 -58.00 Mn
Dec 31, 2018 -122.47 Mn
Dec 31, 2017 -73.59 Mn
Mar 31, 2017 -56.05 Mn
Dec 31, 2016 -46.92 Mn
Sep 30, 2016 -43.99 Mn
Dec 31, 2015 -40.81 Mn