AC Immune (ACIU) Net Margin (2015 - 2026)
AC Immune (ACIU) posted Net Margin of -85.53% for the quarter ended Jun 30, 2026, up 1536.90 percentage points from -1622.43% a year earlier but down 85.52 percentage points from the prior quarter.
AC Immune (ACIU) Net Margin (2015 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at AC Immune was -244.56%, down 132.93 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -1971.65%, down 1785.20 percentage points from the prior year.
- Annual Net Margin shows a five-year change of -1601.42 percentage points (years ended Dec 2020 to Dec 2025).
- In prior years, AC Immune's Net Margin was -186.44% in the year ended Dec 31, 2024 (+179.97 pp), -366.41% in the year ended Dec 31, 2023 (-366.39 pp) and -0.02% in the year ended Dec 31, 2022.
- Quarterly Net Margin has run from a low of -4252.37% in the quarter ended Dec 31, 2025 to a high of 5200315.00% in the quarter ended Dec 31, 2022 over five years.
- On a year-over-year basis, Net Margin increased in three of the last five quarters, with an average year-over-year change of -269.20 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was -0.01% (quarter ended Mar 31, 2026), -4252.37% (quarter ended Dec 31, 2025) and -1688.82% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | AC Immune | 265.55 Mn | 265.55 Mn | - | -85.53% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -85.53% |
| Mar 31, 2026 | -0.01% |
| Dec 31, 2025 | -4,252.37% |
| Sep 30, 2025 | -1,688.82% |
| Jun 30, 2025 | -1,622.43% |
| Mar 31, 2025 | -0.02% |
| Dec 31, 2024 | -1,389.36% |
| Sep 30, 2024 | 21.59% |
| Jun 30, 2024 | -3,312.95% |
| Dec 31, 2022 | 5,200,315.00% |
| Sep 30, 2022 | -343.57% |
| Dec 31, 2020 | -1,956.99% |
| Sep 30, 2020 | -1,691.36% |
| Jun 30, 2020 | -1,453.19% |
| Mar 31, 2020 | -51.97% |
| Dec 31, 2019 | -2,261.16% |
| Sep 30, 2019 | 56.34% |
| Jun 30, 2019 | -1,118.40% |
| Mar 31, 2019 | 84.72% |
| Dec 31, 2018 | -89.38% |
AC Immune Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=ACIU&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "ACIU", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=ACIU&period=max&api_key=YOUR_API_KEY");
const data = await res.json();