TRV GP VI, LLC reported 4 positions worth $232.28M for the quarter ended Jun 30, 2026, up 71.3% on the prior quarter. It opened 1 new position, added to 0, trimmed 0 and exited 0. Its largest holding is Septerna, Inc. at 60.7% of the portfolio.
Reported 13F market value at each quarter end. A change mixes trading with price moves in the positions held.
Dollar value of shares bought and sold each quarter, at that quarter’s price. It counts trading only, not price changes.
How many positions were opened, added to, trimmed or closed each quarter.
Share of reported value in each sector at every quarter end.
| Holding | Change | Change % | Trade Value | Weight |
|---|---|---|---|---|
| SPTX Seaport Therapeutics, Inc. | +2.06M | – | $44.77M | 19.27% |
No positions were reduced this quarter.
| Holding | Shares | Trade Value | Weight |
|---|---|---|---|
| SPTX Seaport Therapeutics, Inc. | +2.06M | $44.77M | 19.27% |
No positions were closed this quarter.
| # | Activity | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | SEPN Septerna, Inc. | Healthcare | 4.21M | $141.05M | 60.72% | 0 | 0.0% | Unchanged | 9.22% |
| 2 | SPTX Seaport Therapeutics, Inc. | Healthcare | 2.06M | $44.77M | 19.27% | +2.06M | – | New | 3.85% |
| 3 | RAPP Rapport Therapeutics, Inc. | Healthcare | 969.2K | $40.39M | 17.39% | 0 | 0.0% | Unchanged | 2.02% |
| 4 | TNGX Tango Therapeutics, Inc. | Healthcare | 194.2K | $6.07M | 2.61% | 0 | 0.0% | Unchanged | 0.12% |
Tip. Select a row to see that position’s full history at Trv Gp Vi.
As of its Q2 2026 13F filing, TRV GP VI, LLC’s five largest positions were Septerna, Inc. (SEPN) at 60.7%, Seaport Therapeutics, Inc. (SPTX) at 19.3%, Rapport Therapeutics, Inc. (RAPP) at 17.4%, Tango Therapeutics, Inc. (TNGX) at 2.6% of the reported portfolio.
TRV GP VI, LLC reported a 13F portfolio worth $232.28M across 4 positions for Q2 2026. That is up 71.3% from the previous quarter.
Its largest purchases by value were Seaport Therapeutics, Inc. ($44.77M). It opened 1 new positions.
From the Form 13F-HR reports TRV GP VI, LLC files with the SEC each quarter, within 45 days of quarter end. A 13F lists long positions in US-listed equities and options; it excludes short positions, cash, bonds and most non-US holdings.
13F data reflects long positions in US-listed equities and options as reported to the SEC up to 45 days after quarter end. It excludes short positions, cash, bonds and most non-US securities, so it is not a complete picture of a manager’s assets.