Crestline Management, L.P. reported 3 positions worth $53.48M for the quarter ended Jun 30, 2026, up 15.6% on the prior quarter. It opened 0 new positions, added to 0, trimmed 1 and exited 0. Its largest holding is Denali Therapeutics Inc. at 91.9% of the portfolio.
Reported 13F market value at each quarter end. A change mixes trading with price moves in the positions held.
Dollar value of shares bought and sold each quarter, at that quarter’s price. It counts trading only, not price changes.
How many positions were opened, added to, trimmed or closed each quarter.
Share of reported value in each sector at every quarter end.
No positions were added to this quarter.
| Holding | Change | Change % | Trade Value | Weight |
|---|---|---|---|---|
| DNLI Denali Therapeutics Inc. | -300.0K | -13.6% | $7.72M | 91.9% |
No new positions this quarter.
No positions were closed this quarter.
| # | Activity | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | DNLI Denali Therapeutics Inc. | Healthcare | 1.91M | $49.14M | 91.9% | -300.0K | -13.6% | Reduced | 1.02% |
| 2 | SANA Sana Biotechnology, Inc. | Healthcare | 755.7K | $2.64M | 4.93% | 0 | 0.0% | Unchanged | 0.25% |
| 3 | EGHT 8X8 Inc | Technology | 990.9K | $1.69M | 3.17% | 0 | 0.0% | Unchanged | 0.69% |
Tip. Select a row to see that position’s full history at Crestline Management.
As of its Q2 2026 13F filing, Crestline Management, L.P.’s five largest positions were Denali Therapeutics Inc. (DNLI) at 91.9%, Sana Biotechnology, Inc. (SANA) at 4.9%, 8X8 Inc (EGHT) at 3.2% of the reported portfolio.
Crestline Management, L.P. reported a 13F portfolio worth $53.48M across 3 positions for Q2 2026. That is up 15.6% from the previous quarter.
Its largest sales by value were Denali Therapeutics Inc. ($7.72M). It exited 0 positions entirely.
From the Form 13F-HR reports Crestline Management, L.P. files with the SEC each quarter, within 45 days of quarter end. A 13F lists long positions in US-listed equities and options; it excludes short positions, cash, bonds and most non-US holdings.
13F data reflects long positions in US-listed equities and options as reported to the SEC up to 45 days after quarter end. It excludes short positions, cash, bonds and most non-US securities, so it is not a complete picture of a manager’s assets.