VCEL vs PGEN vs MESO Stock Comparison

Vericel, Precigen and Mesoblast Prices as of Nov 4, 2026 Peers: Industry group
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VCEL Vericel Corp
$45.48 +10.7% 1M +25.5% 1Y
Market cap
$2.69B
P/E
111.2x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins
PGEN Precigen, Inc.
$5.05 -34.8% 1M +30.2% 1Y
Market cap
$1.45B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins
MESO Mesoblast Ltd
$14.29 +0.5% 1M -8.3% 1Y
Market cap
$1.81B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

8 decided of 12

Vericel leads on 4 of the 12 questions below (Vericel 4, Precigen 3, Mesoblast 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionVCELPGENMESOLeader
Larger companyMarket capitalisation $2.69B $1.45B $1.81B VCEL
Cheaper on earningsLower P/E, profitable companies only 111.2x -4.3x -32.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 89.2x 29.7x — PGEN
Faster revenue growthRevenue growth, trailing twelve months +23.0% +1,875.0% — PGEN
More profitableNet margin, trailing twelve months 7.9% -392.8% — VCEL
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — -1.6x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +25.5% +30.2% -8.3% PGEN
Better 5-year returnAnnualised price return, 5 years -0.2%/yr -0.2%/yr +2.4%/yr MESO
Less volatileAnnualised volatility, 1 year 42.5% 83.8% 57.2% VCEL
Higher overall scoreMean of the five percentile scores vs peers 81/100 54/100 — VCEL

Percentile Scorecard

VCELPGENMESO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisVCELPGENMESO
Valuation 82 #117 of 634 58 #265 of 634 68 #201 of 634
Growth 94 #37 of 607 48 #317 of 607 –
Profitability 89 #65 of 557 59 #229 of 557 –
Financial Health 69 #207 of 654 25 #488 of 654 45 #362 of 654
Shareholder Returns 72 #112 of 400 80 #80 of 400 –
Overall 81 54 –
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MESO ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodVCELPGENMESOSPY
1 month +10.7%-34.8%+0.5% -1.0%
3 months +0.3%-26.7%-4.5% -0.4%
6 months +23.7%+14.8%-9.6% +4.5%
Year to date +26.3%+20.8%-20.8% +12.4%
1 year +25.5%+30.2%-8.3% +13.6%
3 years +23.4%+317.4%+453.9% +76.4%
3 years, per year +7.3%+61.1%+77.0% +20.8%
5 years -1.2%-1.2%+12.3% +63.7%
5 years, per year -0.2%-0.2%+2.4% +10.4%
10 years +2,015.3%-79.9%+60.6% +267.7%
10 years, per year +35.7%-14.8%+4.8% +13.9%

Risk

MeasureVCELPGENMESOSPY
Volatility, 1Y 42.5%83.8%57.2% 12.8%
Downside volatility, 1Y 41.2%80.6%55.1% 12.7%
Beta vs S&P 500, 1Y 0.851.341.45 1.00
Return / volatility, 1Y 0.600.36-0.15 1.06
Max drawdown, 5Y -61.7%-86.9%-87.9% -25.4%
From 52-week high -5.9%-41.0%-31.8% -1.6%
52-week high $48.31$8.56$20.96 $779.14
52-week low $29.34$3.10$11.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleVCELPGENMESO
P/E now vs peer median 95.9xmedian 18.0x -5.4xmedian 18.0x -32.2xmedian 18.0x
P/S now vs peer median 7.6xmedian 9.1x 21.1xmedian 9.1x 15.4xmedian 9.1x
EV/EBITDA now vs peer median 69.0xmedian 16.2x -54.3xmedian 16.2x —median 16.2x
P/FCF now vs peer median 37.7xmedian 21.7x -15.7xmedian 21.7x -41.5xmedian 21.7x
P/B now vs peer median 6.3xmedian 2.2x 41.5xmedian 2.2x 3.3xmedian 2.2x
PEG now vs peer median 1.77median 0.38 0.04median 0.38 —median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsVCELPGENMESO
Revenue $306.30M $85.72M –
Gross profit $228.38M $77.72M –
Operating income $18.24M -$39.50M –
Net income $24.22M -$157.71M –
Free cash flow $61.66M -$115.22M –
R&D $29.17M $32.29M –
EPS (diluted) $0.46 $-0.81 –
Cash & equivalents $125.40M $16.33M $102.91M
Total debt – $93.88M $119.24M
Shares (diluted) 52.31M 413.69M 129.49M
Enterprise value $2.11B $1.14B $1.38B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricVCELPGENMESO
P/E 95.9x -5.4x -32.2x
P/FCF 37.7x -15.7x -41.5x
P/Operating cash flow 33.4x -15.8x –
P/S 7.6x 21.1x 15.4x
P/B 6.3x 41.5x 3.3x
P/Tangible book 6.4x 44.1x 3.3x
EV/EBITDA 69.0x -54.3x –
EV/EBIT 118.7x -47.2x –
EV/Revenue 7.1x 21.7x –
EV/FCF 35.1x -16.2x –
EV/Operating cash flow 31.1x -16.3x –
PEG (3Y EPS CAGR) 1.77 0.04 –

Growth

14 metrics
MetricVCELPGENMESO
Revenue growth (1Y) 23.0% 1,875% –
Revenue CAGR (3Y) 19.8% 57.1% –
Gross profit growth (1Y) 24.8% 259,173% –
Gross profit CAGR (3Y) 23.9% 69.2% –
Operating income growth (1Y) 1,428% 62.1% –
Operating income CAGR (3Y) 47.8% 18.9% –
Net income growth (1Y) 240.8% -26.7% –
Net income CAGR (3Y) 56.6% -108.9% –
EPS growth (1Y) 228.1% -93.8% –
EPS CAGR (3Y) 54.3% -123.2% –
Operating cash flow growth (1Y) 47.5% -72.3% –
Operating cash flow CAGR (3Y) 33.7% -15.9% –
Free cash flow growth (1Y) 842.9% -65.1% –
Free cash flow CAGR (3Y) 43.2% -15.3% –

Profitability

14 metrics
MetricVCELPGENMESO
Gross margin 74.6% 90.7% –
EBITDA margin 10.2% -40.0% –
Operating margin 6.0% -46.1% –
Pretax margin 8.2% -184.0% –
Net margin 7.9% -392.8% –
FCF margin 20.1% -134.4% –
Operating cash flow margin 22.7% -133.2% –
Return on equity 6.9% -494.3% –
Return on assets 5.1% -102.1% –
Return on invested capital – – –
Return on capital employed 4.1% -31.6% –
Asset turnover 0.6x 0.6x –
Cash conversion (OCF / net income) 2.9x 0.7x –
Stock comp / revenue 12.2% 15.3% –

Financial Health

11 metrics
MetricVCELPGENMESO
Debt / assets – 55.1% 15.4%
Debt / equity – 2.2x 0.2x
Net debt / EBITDA – -1.6x –
Debt / FCF – -0.8x –
Liabilities / assets 26.4% 74.4% 26.5%
Equity / assets 73.6% 25.6% 73.5%
Interest coverage 28.5x -4.1x –
Current ratio 5.0x 4.6x 2.4x
Quick ratio 4.5x 3.8x 2.0x
Cash ratio 3.1x 1.3x 1.3x
Altman Z-score 10.69 -10.11 –

Shareholder Returns

7 metrics
MetricVCELPGENMESO
Dividend yield – – –
Net buyback yield -0.3% -0.1% –
Shareholder yield -0.3% -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusVCELPGENMESO
Forward P/E 89.2xFY2026 29.7xFY2026 –
EPS, next fiscal year $0.51FY2026 $0.17FY2026 $-0.15FY2027
EPS growth, next FY +59.4%FY2026 – –
EPS growth, the year after +74.5% +288.2% –
Revenue, next fiscal year $324.56MFY2026 $249.17MFY2026 $188.99MFY2027
Revenue growth, next FY +17.5%FY2026 +2,474.1%FY2026 +57.2%FY2027
Revenue growth, the year after +16.1% +82.3% +110.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersVCELPGENMESO
Held by institutions 100.0% 39.2% 3.0%
Institutions holding 319 211 73
Change in shares held, QoQ +0.4% +4.9% +17.7%
Institutions buying 188 123 34
Institutions selling 99 46 20
Buyers to sellers 1.90 2.67 1.70

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

VCELPGENMESO
VCEL 1.00 0.13 0.11
PGEN 0.13 1.00 0.23
MESO 0.11 0.23 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, VCEL, PGEN and MESO?

Vericel (VCEL) is the largest by market capitalisation: Vericel (VCEL) $2.69B, Precigen (PGEN) $1.45B, Mesoblast (MESO) $1.81B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Vericel (VCEL) +23.0%, Precigen (PGEN) +1,875.0%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Vericel (VCEL) 7.9%, Precigen (PGEN) -392.8%).

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Vericel (VCEL) +25.5%, Precigen (PGEN) +30.2%, Mesoblast (MESO) -8.3%. Over five years, Mesoblast (MESO) compounded fastest (Vericel (VCEL) -0.2%/yr, Precigen (PGEN) -0.2%/yr, Mesoblast (MESO) +2.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Vericel (VCEL) 42.5%, Precigen (PGEN) 83.8%, Mesoblast (MESO) 57.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, VCEL, PGEN and MESO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.