VCEL vs LEGN vs BEAM Stock Comparison

Vericel, Legend Biotech and Beam Therapeutics Prices as of Nov 4, 2026 Peers: Industry group
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VCEL Vericel Corp
$45.48 +10.7% 1M +25.5% 1Y
Market cap
$2.33B
P/E
95.9x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins
LEGN Legend Biotech Corp
$22.77 +21.3% 1M -29.0% 1Y
Market cap
$4.20B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
BEAM Beam Therapeutics Inc.
$27.79 +8.3% 1M +22.2% 1Y
Market cap
$2.88B
P/E
–
Revenue (TTM)
$146.64M
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

8 decided of 12

Vericel leads on 5 of the 12 questions below (Vericel 5, Legend Biotech 2, Beam Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionVCELLEGNBEAMLeader
Larger companyMarket capitalisation $2.33B $4.20B $2.88B LEGN
Cheaper on earningsLower P/E, profitable companies only 95.9x -45.8x -26.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 89.2x — — –
Faster revenue growthRevenue growth, trailing twelve months +23.0% +59.5% +163.3% BEAM
More profitableNet margin, trailing twelve months 7.9% -7.2% -73.9% VCEL
Better return on capitalReturn on invested capital — -4.2% — –
Less leveragedLower net debt / EBITDA — -130.2x 2.5x LEGN
Higher dividend yieldTrailing dividend yield — — 0.00% –
Better 1-year returnPrice return, last 12 months +25.5% -29.0% +22.2% VCEL
Better 5-year returnAnnualised price return, 5 years -0.2%/yr -14.1%/yr -20.9%/yr VCEL
Less volatileAnnualised volatility, 1 year 42.5% 72.7% 70.4% VCEL
Higher overall scoreMean of the five percentile scores vs peers 81/100 74/100 67/100 VCEL

Percentile Scorecard

VCELLEGNBEAM

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisVCELLEGNBEAM
Valuation 82 #117 of 634 88 #77 of 634 54 #291 of 634
Growth 94 #37 of 607 97 #21 of 607 74 #161 of 607
Profitability 89 #65 of 557 80 #110 of 557 64 #204 of 557
Financial Health 69 #207 of 654 60 #263 of 654 79 #141 of 654
Shareholder Returns 72 #112 of 400 44 #223 of 400 66 #135 of 400
Overall 81 74 67
  • VCEL ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodVCELLEGNBEAMSPY
1 month +10.7%+21.3%+8.3% -1.0%
3 months +0.3%+19.5%+2.7% -0.4%
6 months +23.7%-21.4%-14.1% +4.5%
Year to date +26.3%+4.7%+0.3% +12.4%
1 year +25.5%-29.0%+22.2% +13.6%
3 years +23.4%-65.5%+13.5% +76.4%
3 years, per year +7.3%-29.9%+4.3% +20.8%
5 years -1.2%-53.3%-69.0% +63.7%
5 years, per year -0.2%-14.1%-20.9% +10.4%
10 years +2,015.3%—— +267.7%
10 years, per year +35.7%—— +13.9%

Risk

MeasureVCELLEGNBEAMSPY
Volatility, 1Y 42.5%72.7%70.4% 12.8%
Downside volatility, 1Y 41.2%62.9%63.7% 12.7%
Beta vs S&P 500, 1Y 0.850.532.10 1.00
Return / volatility, 1Y 0.60-0.400.32 1.06
Max drawdown, 5Y -61.7%-78.2%-85.3% -25.4%
From 52-week high -5.9%-37.2%-26.7% -1.6%
52-week high $48.31$36.28$37.92 $779.14
52-week low $29.34$16.65$20.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleVCELLEGNBEAM
P/E now vs peer median 95.9xmedian 18.0x -45.8xmedian 18.0x -26.9xmedian 18.0x
P/S now vs peer median 7.6xmedian 9.1x 3.3xmedian 9.1x 19.6xmedian 9.1x
EV/EBITDA now vs peer median 69.0xmedian 16.2x 927.8xmedian 16.2x -5.2xmedian 16.2x
P/FCF now vs peer median 37.7xmedian 21.7x -65.0xmedian 21.7x -7.2xmedian 21.7x
P/B now vs peer median 6.3xmedian 2.2x 3.4xmedian 2.2x 3.0xmedian 2.2x
PEG now vs peer median 1.77median 0.38 -0.97median 0.38 -0.74median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsVCELLEGNBEAM
Revenue $306.30M $1.27B $146.64M
Gross profit $228.38M $727.10M –
Operating income $18.24M -$55.25M -$392.54M
Net income $24.22M -$80.39M -$108.35M
Free cash flow $61.66M -$64.60M -$398.24M
R&D $29.17M $396.15M $409.01M
EPS (diluted) $0.46 $-0.50 $-1.03
Cash & equivalents $125.40M $672.90M $213.27M
Total debt – $156.40M $100.36M
Shares (diluted) 52.31M 184.32M 104.70M
Enterprise value $1.75B $1.70B -$1.78B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricVCELLEGNBEAM
P/E 95.9x -45.8x -26.9x
P/FCF 37.7x -65.0x -7.2x
P/Operating cash flow 33.4x -46.9x -7.4x
P/S 7.6x 3.3x 19.6x
P/B 6.3x 3.4x 3.0x
P/Tangible book 6.4x 3.4x 3.0x
EV/EBITDA 69.0x 927.8x -5.2x
EV/EBIT 118.7x -66.6x -4.9x
EV/Revenue 7.1x 2.9x 13.2x
EV/FCF 35.1x -57.0x -4.9x
EV/Operating cash flow 31.1x -41.2x -5.0x
PEG (3Y EPS CAGR) 1.77 -0.97 -0.74

Growth

14 metrics
MetricVCELLEGNBEAM
Revenue growth (1Y) 23.0% 59.5% 163.3%
Revenue CAGR (3Y) 19.8% 97.6% 21.6%
Gross profit growth (1Y) 24.8% 42.4% –
Gross profit CAGR (3Y) 23.9% 147.5% –
Operating income growth (1Y) 1,428% 75.3% 15.8%
Operating income CAGR (3Y) 47.8% 49.1% 0.5%
Net income growth (1Y) 240.8% 75.3% 73.8%
Net income CAGR (3Y) 56.6% 46.7% 29.8%
EPS growth (1Y) 228.1% 72.0% 74.3%
EPS CAGR (3Y) 54.3% 47.0% 36.1%
Operating cash flow growth (1Y) 47.5% 67.5% -14.9%
Operating cash flow CAGR (3Y) 33.7% 37.1% -3.2%
Free cash flow growth (1Y) 842.9% 77.8% -13.0%
Free cash flow CAGR (3Y) 43.2% 44.5% -0.5%

Profitability

14 metrics
MetricVCELLEGNBEAM
Gross margin 74.6% 57.2% –
EBITDA margin 10.2% 0.3% -252.4%
Operating margin 6.0% -4.3% -267.7%
Pretax margin 8.2% -4.4% -73.2%
Net margin 7.9% -7.2% -73.9%
FCF margin 20.1% -5.1% -271.6%
Operating cash flow margin 22.7% -7.0% -265.0%
Return on equity 6.9% -8.3% -10.6%
Return on assets 5.1% -5.5% -8.1%
Return on invested capital – -4.2% –
Return on capital employed 4.1% -4.3% -31.5%
Asset turnover 0.6x 0.8x 0.1x
Cash conversion (OCF / net income) 2.9x 1.1x 3.6x
Stock comp / revenue 12.2% 5.2% 52.7%

Financial Health

11 metrics
MetricVCELLEGNBEAM
Debt / assets – 8.9% 7.9%
Debt / equity – 0.1x 0.1x
Net debt / EBITDA – -130.2x 2.5x
Debt / FCF – -2.4x -0.3x
Liabilities / assets 26.4% 29.8% 24.9%
Equity / assets 73.6% 70.2% 75.1%
Interest coverage 28.5x -4.8x –
Current ratio 5.0x 3.0x 13.0x
Quick ratio 4.5x 1.7x 12.7x
Cash ratio 3.1x 1.7x 12.7x
Altman Z-score 10.69 7.00 3.27

Shareholder Returns

7 metrics
MetricVCELLEGNBEAM
Dividend yield – – –
Net buyback yield -0.3% -5.1% -0.5%
Shareholder yield -0.3% -5.1% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusVCELLEGNBEAM
Forward P/E 89.2xFY2026 – –
EPS, next fiscal year $0.51FY2026 $-0.04FY2026 $-4.22FY2026
EPS growth, next FY +59.4%FY2026 – –
EPS growth, the year after +74.5% – –
Revenue, next fiscal year $324.56MFY2026 $1.37BFY2026 $49.46MFY2026
Revenue growth, next FY +17.5%FY2026 +32.9%FY2026 -64.6%FY2026
Revenue growth, the year after +16.1% +35.9% +23.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersVCELLEGNBEAM
Held by institutions 100.0% 55.9% 100.0%
Institutions holding 319 218 277
Change in shares held, QoQ +0.4% +7.3% +1.0%
Institutions buying 188 117 154
Institutions selling 99 78 75
Buyers to sellers 1.90 1.50 2.05

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

VCELLEGNBEAM
VCEL 1.00 0.15 0.23
LEGN 0.15 1.00 0.10
BEAM 0.23 0.10 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, VCEL, LEGN and BEAM?

Legend Biotech (LEGN) is the largest by market capitalisation: Vericel (VCEL) $2.33B, Legend Biotech (LEGN) $4.20B, Beam Therapeutics (BEAM) $2.88B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Vericel (VCEL) +23.0%, Legend Biotech (LEGN) +59.5%, Beam Therapeutics (BEAM) +163.3%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Vericel (VCEL) 7.9%, Legend Biotech (LEGN) -7.2%, Beam Therapeutics (BEAM) -73.9%).

Which stock has performed better?

Over the past year Vericel (VCEL) returned the most: Vericel (VCEL) +25.5%, Legend Biotech (LEGN) -29.0%, Beam Therapeutics (BEAM) +22.2%. Over five years, Vericel (VCEL) compounded fastest (Vericel (VCEL) -0.2%/yr, Legend Biotech (LEGN) -14.1%/yr, Beam Therapeutics (BEAM) -20.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Vericel (VCEL) 42.5%, Legend Biotech (LEGN) 72.7%, Beam Therapeutics (BEAM) 70.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, VCEL, LEGN and BEAM?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.