VCEL vs BEAM vs PGEN Stock Comparison

Vericel, Beam Therapeutics and Precigen Prices as of Oct 28, 2026 Peers: Industry group
VCEL Vericel Corp
$41.09 +2.1% 1M +11.6% 1Y
Market cap
$2.10B
P/E
86.6x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins
BEAM Beam Therapeutics Inc.
$28.78 +18.8% 1M +8.9% 1Y
Market cap
$2.97B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
PGEN Precigen, Inc.
$6.08 -22.2% 1M +49.8% 1Y
Market cap
$2.18B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
5 wins

Head to Head

9 decided of 12

Precigen leads on 5 of the 12 questions below (Precigen 5, Vericel 3, Beam Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionVCELBEAMPGENLeader
Larger companyMarket capitalisation $2.10B $2.97B $2.18B BEAM
Cheaper on earningsLower P/E, profitable companies only 86.6x -35.1x -6.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 80.6x — 35.8x PGEN
Faster revenue growthRevenue growth, trailing twelve months +23.0% +158.9% +1,875.0% PGEN
More profitableNet margin, trailing twelve months 7.9% -54.7% -392.8% VCEL
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — 3.0x -1.6x PGEN
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months +11.6% +8.9% +49.8% PGEN
Better 5-year returnAnnualised price return, 5 years -2.2%/yr -20.2%/yr +4.7%/yr PGEN
Less volatileAnnualised volatility, 1 year 41.1% 70.7% 77.7% VCEL
Higher overall scoreMean of the five percentile scores vs peers 81/100 69/100 55/100 VCEL

Percentile Scorecard

VCELBEAMPGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisVCELBEAMPGEN
Valuation 82 #112 of 625 57 #272 of 625 58 #265 of 625
Growth 94 #38 of 602 77 #139 of 602 48 #311 of 602
Profitability 88 #65 of 549 64 #197 of 549 59 #225 of 549
Financial Health 69 #206 of 654 81 #123 of 654 27 #480 of 654
Shareholder Returns 73 #100 of 367 68 #119 of 367 82 #66 of 367
Overall 81 69 55
  • VCEL ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodVCELBEAMPGENSPY
1 month +2.1%+18.8%-22.2% +0.9%
3 months -11.9%+10.6%+11.6% +5.9%
6 months +22.9%-2.0%+47.6% +8.5%
Year to date +14.1%+3.8%+45.5% +13.3%
1 year +11.6%+8.9%+49.8% +12.4%
3 years +25.2%+54.6%+502.0% +88.1%
3 years, per year +7.8%+15.6%+82.0% +23.5%
5 years -10.7%-67.6%+25.9% +68.2%
5 years, per year -2.2%-20.2%+4.7% +11.0%
10 years +1,648.5%—-76.4% +263.4%
10 years, per year +33.1%—-13.4% +13.8%

Risk

MeasureVCELBEAMPGENSPY
Volatility, 1Y 41.1%70.7%77.7% 12.7%
Downside volatility, 1Y 40.6%64.0%69.0% 12.7%
Beta vs S&P 500, 1Y 0.732.091.43 1.00
Return / volatility, 1Y 0.280.130.64 0.98
Max drawdown, 5Y -64.7%-85.3%-87.8% -25.4%
From 52-week high -14.9%-24.1%-29.0% -0.9%
52-week high $48.31$37.92$8.56 $779.14
52-week low $29.34$20.60$3.10 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleVCELBEAMPGEN
P/E now vs peer median 86.6xmedian 17.4x -35.1xmedian 17.4x -6.4xmedian 17.4x
P/S now vs peer median 6.9xmedian 9.1x 19.0xmedian 9.1x 25.4xmedian 9.1x
EV/EBITDA now vs peer median 61.8xmedian 17.1x -5.4xmedian 17.1x -65.1xmedian 17.1x
P/FCF now vs peer median 34.1xmedian 19.0x -8.0xmedian 19.0x -18.9xmedian 19.0x
P/B now vs peer median 5.7xmedian 2.2x 2.8xmedian 2.2x 50.0xmedian 2.2x
PEG now vs peer median 1.60median 0.34 -0.83median 0.34 0.05median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsVCELBEAMPGEN
Revenue $306.30M $156.04M $85.72M
Gross profit $228.38M – $77.72M
Operating income $18.24M -$378.02M -$39.50M
Net income $24.22M -$86.52M -$157.71M
Free cash flow $61.66M -$372.77M -$115.22M
R&D $29.17M $408.66M $32.29M
EPS (diluted) $0.46 $-0.82 $-0.81
Cash & equivalents $125.40M $219.83M $16.33M
Total debt – $100.26M $93.88M
Shares (diluted) 52.31M 104.33M 413.69M
Enterprise value $1.52B -$1.71B $1.86B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricVCELBEAMPGEN
P/E 86.6x -35.1x -6.4x
P/FCF 34.1x -8.0x -18.9x
P/Operating cash flow 30.2x -8.3x -19.1x
P/S 6.9x 19.0x 25.4x
P/B 5.7x 2.8x 50.0x
P/Tangible book 5.8x 2.8x 53.0x
EV/EBITDA 61.8x -5.4x -65.1x
EV/EBIT 106.4x -5.1x -56.5x
EV/Revenue 6.3x 12.3x 26.0x
EV/FCF 31.5x -5.1x -19.4x
EV/Operating cash flow 27.8x -5.3x -19.6x
PEG (3Y EPS CAGR) 1.60 -0.83 0.05

Growth

14 metrics
MetricVCELBEAMPGEN
Revenue growth (1Y) 23.0% 158.9% 1,875%
Revenue CAGR (3Y) 19.8% 24.9% 57.1%
Gross profit growth (1Y) 24.8% – 259,173%
Gross profit CAGR (3Y) 23.9% – 69.2%
Operating income growth (1Y) 1,428% 15.2% 62.1%
Operating income CAGR (3Y) 47.8% 0.3% 18.9%
Net income growth (1Y) 240.8% 78.2% -26.7%
Net income CAGR (3Y) 56.6% 35.8% -108.9%
EPS growth (1Y) 228.1% 79.0% -93.8%
EPS CAGR (3Y) 54.3% 42.4% -123.2%
Operating cash flow growth (1Y) 47.5% -4.2% -72.3%
Operating cash flow CAGR (3Y) 33.7% -2.0% -15.9%
Free cash flow growth (1Y) 842.9% -4.8% -65.1%
Free cash flow CAGR (3Y) 43.2% 0.7% -15.3%

Profitability

14 metrics
MetricVCELBEAMPGEN
Gross margin 74.6% – 90.7%
EBITDA margin 10.2% -228.0% -40.0%
Operating margin 6.0% -242.3% -46.1%
Pretax margin 8.2% -54.4% -184.0%
Net margin 7.9% -54.7% -392.8%
FCF margin 20.1% -238.9% -134.4%
Operating cash flow margin 22.7% -230.3% -133.2%
Return on equity 6.9% -7.6% -494.3%
Return on assets 5.1% -5.9% -102.1%
Return on invested capital – – –
Return on capital employed 4.1% -27.9% -31.6%
Asset turnover 0.6x 0.1x 0.6x
Cash conversion (OCF / net income) 2.9x 4.2x 0.7x
Stock comp / revenue 12.2% 52.2% 15.3%

Financial Health

11 metrics
MetricVCELBEAMPGEN
Debt / assets – 7.2% 55.1%
Debt / equity – 0.1x 2.2x
Net debt / EBITDA – 3.0x -1.6x
Debt / FCF – -0.3x -0.8x
Liabilities / assets 26.4% 23.0% 74.4%
Equity / assets 73.6% 77.0% 25.6%
Interest coverage 28.5x – -4.1x
Current ratio 5.0x 14.6x 4.6x
Quick ratio 4.5x 14.3x 3.8x
Cash ratio 3.1x 14.3x 1.3x
Altman Z-score 9.67 3.84 -8.36

Shareholder Returns

7 metrics
MetricVCELBEAMPGEN
Dividend yield – – –
Net buyback yield -0.3% -0.5% -0.1%
Shareholder yield -0.3% -0.5% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusVCELBEAMPGEN
Forward P/E 80.6xFY2026 – 35.8xFY2026
EPS, next fiscal year $0.51FY2026 $-4.22FY2026 $0.17FY2026
EPS growth, next FY +59.4%FY2026 – –
EPS growth, the year after +74.5% – +288.2%
Revenue, next fiscal year $324.56MFY2026 $49.46MFY2026 $249.17MFY2026
Revenue growth, next FY +17.5%FY2026 -64.6%FY2026 +2,474.1%FY2026
Revenue growth, the year after +16.1% +23.6% +82.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersVCELBEAMPGEN
Held by institutions 100.0% 100.0% 39.2%
Institutions holding 317 277 210
Change in shares held, QoQ +0.4% +1.0% +4.9%
Institutions buying 187 154 123
Institutions selling 98 75 46
Buyers to sellers 1.91 2.05 2.67

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

VCELBEAMPGEN
VCEL 1.00 0.21 0.17
BEAM 0.21 1.00 0.25
PGEN 0.17 0.25 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, VCEL, BEAM and PGEN?

Beam Therapeutics (BEAM) is the largest by market capitalisation: Vericel (VCEL) $2.10B, Beam Therapeutics (BEAM) $2.97B, Precigen (PGEN) $2.18B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Vericel (VCEL) +23.0%, Beam Therapeutics (BEAM) +158.9%, Precigen (PGEN) +1,875.0%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Vericel (VCEL) 7.9%, Beam Therapeutics (BEAM) -54.7%, Precigen (PGEN) -392.8%).

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Vericel (VCEL) +11.6%, Beam Therapeutics (BEAM) +8.9%, Precigen (PGEN) +49.8%. Over five years, Precigen (PGEN) compounded fastest (Vericel (VCEL) -2.2%/yr, Beam Therapeutics (BEAM) -20.2%/yr, Precigen (PGEN) +4.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (Vericel (VCEL) 41.1%, Beam Therapeutics (BEAM) 70.7%, Precigen (PGEN) 77.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, VCEL, BEAM and PGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.