TXG vs TMO vs DHR Stock Comparison

10x Genomics, Thermo Fisher Scientific and Danaher Prices as of Oct 26, 2026 Peers: Industry group
TXG 10x Genomics, Inc.
$72.96 -14.9% 1M +429.8% 1Y
Market cap
$10.23B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins
DHR Danaher Corp /De/
$232.95 +3.7% 1M +4.5% 1Y
Market cap
$163.74B
P/E
40.9x
Revenue (TTM)
$25.11B
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

9 decided of 12

Thermo Fisher Scientific leads on 5 of the 12 questions below (Thermo Fisher Scientific 5, Danaher 2, 10x Genomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGTMODHRLeader
Larger companyMarket capitalisation $10.23B $259.05B $163.74B TMO
Cheaper on earningsLower P/E, profitable companies only -136.2x 36.6x 40.9x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 26.4x 25.6x DHR
Faster revenue growthRevenue growth, trailing twelve months -4.3% +8.3% +4.6% TMO
More profitableNet margin, trailing twelve months -12.2% — 15.9% DHR
Better return on capitalReturn on invested capital — — 5.7% –
Less leveragedLower net debt / EBITDA — — 2.9x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +429.8% +19.6% +4.5% TXG
Better 5-year returnAnnualised price return, 5 years -14.4%/yr +2.3%/yr -5.3%/yr TMO
Less volatileAnnualised volatility, 1 year 73.8% 29.9% 30.7% TMO
Higher overall scoreMean of the five percentile scores vs peers 61/100 51/100 59/100 TXG

Percentile Scorecard

TXGTMODHR

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGTMODHR
Valuation 43 #130 of 228 49 #116 of 228 67 #75 of 228
Growth 66 #76 of 221 40 #133 of 221 21 #176 of 221
Profitability 63 #77 of 208 70 #63 of 208 88 #26 of 208
Financial Health 68 #78 of 239 – 46 #130 of 239
Shareholder Returns 67 #46 of 137 44 #77 of 137 76 #34 of 137
Overall 61 51 59
  • TXG ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • DHR ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGTMODHRSPY
1 month -14.9%+1.7%+3.7% -0.8%
3 months +58.9%+22.4%+18.5% +3.5%
6 months +227.5%+46.3%+29.0% +7.0%
Year to date +347.3%+18.2%+1.8% +12.2%
1 year +429.8%+19.6%+4.5% +13.0%
3 years +100.4%+58.7%+24.0% +86.3%
3 years, per year +26.1%+16.7%+7.4% +23.1%
5 years -54.1%+11.8%-23.7% +68.6%
5 years, per year -14.4%+2.3%-5.3% +11.0%
10 years —+362.6%+199.7% +258.0%
10 years, per year —+16.6%+11.6% +13.6%

Risk

MeasureTXGTMODHRSPY
Volatility, 1Y 73.8%29.9%30.7% 12.7%
Downside volatility, 1Y 66.1%28.3%31.8% 12.7%
Beta vs S&P 500, 1Y 2.210.620.45 1.00
Return / volatility, 1Y 5.820.660.15 1.02
Max drawdown, 5Y -96.1%-41.5%-50.8% -25.4%
From 52-week high -25.4%-1.7%-3.8% -1.8%
52-week high $97.74$696.55$242.05 $779.14
52-week low $12.44$438.34$161.91 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGTMODHR
P/E now vs peer median -126.2xmedian 30.6x 35.9xmedian 30.6x 41.0xmedian 30.6x
P/S now vs peer median 15.4xmedian 3.0x 5.3xmedian 3.0x 6.5xmedian 3.0x
EV/EBITDA now vs peer median -212.9xmedian 17.5x —median 17.5x 24.3xmedian 17.5x
P/FCF now vs peer median 78.3xmedian 23.3x 34.0xmedian 23.3x 30.0xmedian 23.3x
P/B now vs peer median 11.5xmedian 2.4x 4.6xmedian 2.4x 3.1xmedian 2.4x
PEG now vs peer median -4.70median 0.87 4.74median 0.87 -3.28median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGTMODHR
Revenue $616.91M $47.35B $25.11B
Gross profit $432.03M – $14.69B
Operating income -$88.38M $8.47B $5.13B
Net income -$75.13M $7.09B $4.00B
Free cash flow $121.44M – $5.47B
R&D $226.80M $1.40B $1.62B
EPS (diluted) $-0.58 $19.06 $5.66
Cash & equivalents – $5.46B $4.35B
Total debt – – $26.56B
Shares (diluted) 129.98M 371.00M 707.60M
Enterprise value $10.04B $259.05B $147.55B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGTMODHR
P/E -126.2x 35.9x 41.0x
P/FCF 78.3x 34.0x 30.0x
P/Operating cash flow 74.8x 27.2x 24.7x
P/S 15.4x 5.3x 6.5x
P/B 11.5x 4.6x 3.1x
P/Tangible book 12.4x 6.9x 5.2x
EV/EBITDA -212.9x – 24.3x
EV/EBIT -107.0x – 36.3x
EV/Revenue 15.3x 5.3x 7.4x
EV/FCF 77.9x – 34.0x
EV/Operating cash flow 74.4x 27.2x 28.0x
PEG (3Y EPS CAGR) -4.70 4.74 -3.28

Growth

14 metrics
MetricTXGTMODHR
Revenue growth (1Y) -4.3% 8.3% 4.6%
Revenue CAGR (3Y) 2.8% 2.9% -0.5%
Gross profit growth (1Y) -3.5% – 2.6%
Gross profit CAGR (3Y) 1.1% – -0.9%
Operating income growth (1Y) 12.1% 12.8% 16.1%
Operating income CAGR (3Y) 20.9% 7.2% -7.1%
Net income growth (1Y) 11.2% 7.9% 17.3%
Net income CAGR (3Y) 24.2% 6.2% -14.3%
EPS growth (1Y) 14.9% 9.7% 19.2%
EPS CAGR (3Y) 26.8% 7.6% -12.5%
Operating cash flow growth (1Y) 89.8% 21.9% 7.6%
Operating cash flow CAGR (3Y) 135.5% 4.5% -7.6%
Free cash flow growth (1Y) 113.5% – 12.4%
Free cash flow CAGR (3Y) 44.7% – -9.0%

Profitability

14 metrics
MetricTXGTMODHR
Gross margin 70.0% – 58.5%
EBITDA margin -7.2% – 30.5%
Operating margin -14.3% – 20.4%
Pretax margin -12.1% – 19.0%
Net margin -12.2% – 15.9%
FCF margin 19.7% – 21.8%
Operating cash flow margin 20.6% 19.7% 26.4%
Return on equity -9.2% 13.2% 7.6%
Return on assets -7.3% 6.2% 4.5%
Return on invested capital – – 5.7%
Return on capital employed -9.8% – 6.4%
Asset turnover 0.6x 0.4x 0.3x
Cash conversion (OCF / net income) -1.7x 1.3x 1.7x
Stock comp / revenue 16.0% – 1.2%

Financial Health

11 metrics
MetricTXGTMODHR
Debt / assets – – 28.8%
Debt / equity – – 0.5x
Net debt / EBITDA – – 2.9x
Debt / FCF – – 4.9x
Liabilities / assets 19.9% – 43.1%
Equity / assets 80.1% 47.9% 56.9%
Interest coverage – – 17.6x
Current ratio 5.7x 1.8x 1.7x
Quick ratio 0.8x – 1.0x
Cash ratio 0.4x – 0.5x
Altman Z-score 26.75 – 3.72

Shareholder Returns

7 metrics
MetricTXGTMODHR
Dividend yield – 0.3% 0.7%
Net buyback yield -0.1% – 1.8%
Shareholder yield -0.1% 0.3% 2.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGTMODHR
Forward P/E – 26.4xFY2026 25.6xFY2026
EPS, next fiscal year $-0.79FY2026 $25.91FY2026 $9.11FY2026
EPS growth, next FY – +13.3%FY2026 +16.8%FY2026
EPS growth, the year after – +2.0% +8.0%
Revenue, next fiscal year $580.42MFY2026 $50.12BFY2026 $27.01BFY2026
Revenue growth, next FY -9.7%FY2026 +12.5%FY2026 +9.9%FY2026
Revenue growth, the year after +24.6% -2.8% -1.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGTMODHR
Held by institutions 100.0% 90.2% 81.9%
Institutions holding 389 2,621 2,115
Change in shares held, QoQ +2.4% +0.8% +1.1%
Institutions buying 197 1,141 837
Institutions selling 137 1,144 1,015
Buyers to sellers 1.44 1.00 0.82

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGTMODHR
TXG 1.00 0.50 0.33
TMO 0.50 1.00 0.72
DHR 0.33 0.72 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, TXG, TMO and DHR?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: 10x Genomics (TXG) $10.23B, Thermo Fisher Scientific (TMO) $259.05B, Danaher (DHR) $163.74B.

Which stock is cheaper, TXG, TMO and DHR?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (10x Genomics (TXG) -136.2x, Thermo Fisher Scientific (TMO) 36.6x, Danaher (DHR) 40.9x). On next year's consensus earnings, Danaher (DHR) is cheapest (Thermo Fisher Scientific (TMO) 26.4x, Danaher (DHR) 25.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Thermo Fisher Scientific (TMO) +8.3%, Danaher (DHR) +4.6%.

Which company is more profitable?

Danaher (DHR) has the highest net margin (10x Genomics (TXG) -12.2%, Danaher (DHR) 15.9%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +429.8%, Thermo Fisher Scientific (TMO) +19.6%, Danaher (DHR) +4.5%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (10x Genomics (TXG) -14.4%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr, Danaher (DHR) -5.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (10x Genomics (TXG) 73.8%, Thermo Fisher Scientific (TMO) 29.9%, Danaher (DHR) 30.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TXG, TMO and DHR?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.