TXG vs STE Stock Comparison

10x Genomics and Steris Prices as of Oct 26, 2026 Peers: Industry group
TXG 10x Genomics, Inc.
$72.96 -14.9% 1M +429.8% 1Y
Market cap
$10.25B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
1 win
STE STERIS plc
$230.10 +10.1% 1M -4.4% 1Y
Market cap
$22.29B
P/E
27.7x
Revenue (TTM)
$6.04B
Div. yield
0.01%
Medical Devices Healthcare
6 wins

Head to Head

7 decided of 12

Steris leads on 6 of the 12 questions below (Steris 6, 10x Genomics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGSTELeader
Larger companyMarket capitalisation $10.25B $22.29B STE
Cheaper on earningsLower P/E, profitable companies only -136.4x 27.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 19.9x –
Faster revenue growthRevenue growth, trailing twelve months -4.3% +8.4% STE
More profitableNet margin, trailing twelve months -12.2% 13.3% STE
Better return on capitalReturn on invested capital — 9.3% –
Less leveragedLower net debt / EBITDA — 0.9x –
Higher dividend yieldTrailing dividend yield 0.00% 0.01% –
Better 1-year returnPrice return, last 12 months +429.8% -4.4% TXG
Better 5-year returnAnnualised price return, 5 years -14.4%/yr -0.2%/yr STE
Less volatileAnnualised volatility, 1 year 73.8% 26.3% STE
Higher overall scoreMean of the five percentile scores vs peers 61/100 76/100 STE

Percentile Scorecard

TXGSTE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGSTE
Valuation 43 #130 of 228 84 #38 of 228
Growth 66 #76 of 221 71 #64 of 221
Profitability 63 #77 of 208 87 #27 of 208
Financial Health 68 #78 of 239 63 #89 of 239
Shareholder Returns 67 #46 of 137 73 #38 of 137
Overall 61 76
  • TXG ranked among 248 companies in Medical Devices and Diagnostics
  • STE ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGSTESPY
1 month -14.9%+10.1% -0.8%
3 months +58.9%+5.3% +3.5%
6 months +227.5%+3.6% +7.0%
Year to date +347.3%-9.2% +12.2%
1 year +429.8%-4.4% +13.0%
3 years +100.4%+9.9% +86.3%
3 years, per year +26.1%+3.2% +23.1%
5 years -54.1%-0.9% +68.6%
5 years, per year -14.4%-0.2% +11.0%
10 years —+238.8% +258.0%
10 years, per year —+13.0% +13.6%

Risk

MeasureTXGSTESPY
Volatility, 1Y 73.8%26.3% 12.7%
Downside volatility, 1Y 66.1%25.7% 12.7%
Beta vs S&P 500, 1Y 2.210.40 1.00
Return / volatility, 1Y 5.82-0.17 1.02
Max drawdown, 5Y -96.1%-36.5% -25.4%
From 52-week high -25.4%-14.3% -1.8%
52-week high $97.74$268.65 $779.14
52-week low $12.44$199.40 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGSTE
P/E now vs peer median -126.2xmedian 30.6x 27.9xmedian 30.6x
P/S now vs peer median 15.4xmedian 3.0x 3.7xmedian 3.0x
EV/EBITDA now vs peer median -212.9xmedian 17.5x 14.6xmedian 17.5x
P/FCF now vs peer median 78.3xmedian 23.3x 24.2xmedian 23.3x
P/B now vs peer median 11.5xmedian 2.4x 3.1xmedian 2.4x
PEG now vs peer median -4.70median 0.87 0.31median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGSTE
Revenue $616.91M $6.04B
Gross profit $432.03M $2.68B
Operating income -$88.38M $1.14B
Net income -$75.13M $808.10M
Free cash flow $121.44M $925.60M
R&D $226.80M $115.10M
EPS (diluted) $-0.58 $8.22
Cash & equivalents – $482.30M
Total debt – $1.89B
Shares (diluted) 129.98M 97.90M
Enterprise value $10.05B $20.62B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGSTE
P/E -126.2x 27.9x
P/FCF 78.3x 24.2x
P/Operating cash flow 74.8x 17.4x
P/S 15.4x 3.7x
P/B 11.5x 3.1x
P/Tangible book 12.4x 4.0x
EV/EBITDA -212.9x 14.6x
EV/EBIT -107.0x 20.9x
EV/Revenue 15.3x 3.9x
EV/FCF 77.9x 25.8x
EV/Operating cash flow 74.4x 18.5x
PEG (3Y EPS CAGR) -4.70 0.31

Growth

14 metrics
MetricTXGSTE
Revenue growth (1Y) -4.3% 8.4%
Revenue CAGR (3Y) 2.8% 9.0%
Gross profit growth (1Y) -3.5% 9.1%
Gross profit CAGR (3Y) 1.1% 9.6%
Operating income growth (1Y) 12.1% 23.1%
Operating income CAGR (3Y) 20.9% 11.2%
Net income growth (1Y) 11.2% 24.6%
Net income CAGR (3Y) 24.2% 89.1%
EPS growth (1Y) 14.9% 25.7%
EPS CAGR (3Y) 26.8% 89.8%
Operating cash flow growth (1Y) 89.8% 1.9%
Operating cash flow CAGR (3Y) 135.5% 16.9%
Free cash flow growth (1Y) 113.5% 1.8%
Free cash flow CAGR (3Y) 44.7% 23.3%

Profitability

14 metrics
MetricTXGSTE
Gross margin 70.0% 44.4%
EBITDA margin -7.2% 27.0%
Operating margin -14.3% 18.9%
Pretax margin -12.1% 18.0%
Net margin -12.2% 13.3%
FCF margin 19.7% 15.3%
Operating cash flow margin 20.6% 21.3%
Return on equity -9.2% 11.2%
Return on assets -7.3% 7.5%
Return on invested capital – 9.3%
Return on capital employed -9.8% 12.1%
Asset turnover 0.6x 0.6x
Cash conversion (OCF / net income) -1.7x 1.6x
Stock comp / revenue 16.0% 1.0%

Financial Health

11 metrics
MetricTXGSTE
Debt / assets – 17.6%
Debt / equity – 0.3x
Net debt / EBITDA – 0.9x
Debt / FCF – 2.0x
Liabilities / assets 19.9% 32.7%
Equity / assets 80.1% 67.3%
Interest coverage – 18.8x
Current ratio 5.7x 1.9x
Quick ratio 0.8x 1.2x
Cash ratio 0.4x 0.4x
Altman Z-score 26.75 5.28

Shareholder Returns

7 metrics
MetricTXGSTE
Dividend yield – 1.1%
Net buyback yield -0.1% 1.5%
Shareholder yield -0.1% 2.6%
Payout ratio (earnings) – 30.6%
Payout ratio (FCF) – 26.7%
Dividend growth (1Y) – 9.9%
Dividend CAGR (3Y) – 9.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGSTE
Forward P/E – 19.9xFY2026
EPS, next fiscal year $-0.79FY2026 $11.56FY2026
EPS growth, next FY – +13.7%FY2026
EPS growth, the year after – +13.2%
Revenue, next fiscal year $580.42MFY2026 $6.62BFY2026
Revenue growth, next FY -9.7%FY2026 +11.5%FY2026
Revenue growth, the year after +24.6% -0.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGSTE
Held by institutions 100.0% 97.1%
Institutions holding 389 829
Change in shares held, QoQ +2.4% +1.1%
Institutions buying 197 405
Institutions selling 137 300
Buyers to sellers 1.44 1.35

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGSTE
TXG 1.00 0.19
STE 0.19 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, TXG and STE?

Steris (STE) is the largest by market capitalisation: 10x Genomics (TXG) $10.25B, Steris (STE) $22.29B.

Which company is growing faster?

Steris (STE) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Steris (STE) +8.4%.

Which company is more profitable?

Steris (STE) has the highest net margin (10x Genomics (TXG) -12.2%, Steris (STE) 13.3%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +429.8%, Steris (STE) -4.4%. Over five years, Steris (STE) compounded fastest (10x Genomics (TXG) -14.4%/yr, Steris (STE) -0.2%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: 10x Genomics (TXG) 0.00%, Steris (STE) 0.01%. 10x Genomics (TXG) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Steris (STE) has been the steadiest (10x Genomics (TXG) 73.8%, Steris (STE) 26.3%). Volatility measures how widely the price swings, not the risk of the business.

Do TXG and STE move together?

Their daily returns over the past year have a correlation of 0.19, a weak relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, TXG and STE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Steris (STE) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.