TXG vs DHR vs SGMOQ Stock Comparison

10x Genomics, Danaher and Sangamo Therapeutics Prices as of Oct 27, 2026 Peers: Industry group
TXG 10x Genomics, Inc.
$78.02 -9.0% 1M +474.1% 1Y
Market cap
$10.16B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins
DHR Danaher Corp /De/
$232.08 +3.3% 1M +5.0% 1Y
Market cap
$163.13B
P/E
40.9x
Revenue (TTM)
$25.11B
Div. yield
0.65%
Life Sciences Tools Healthcare
5 wins

Head to Head

7 decided of 12

Danaher leads on 5 of the 12 questions below (Danaher 5, 10x Genomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionTXGDHRSGMOQLeader
Larger companyMarket capitalisation $10.16B $163.13B $33.62M DHR
Cheaper on earningsLower P/E, profitable companies only -135.0x 40.9x -0.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 25.5x — –
Faster revenue growthRevenue growth, trailing twelve months -4.3% +4.6% -31.6% DHR
More profitableNet margin, trailing twelve months -12.2% 15.9% -310.8% DHR
Better return on capitalReturn on invested capital — 5.7% — –
Less leveragedLower net debt / EBITDA — 2.9x — –
Higher dividend yieldTrailing dividend yield — 0.65% — –
Better 1-year returnPrice return, last 12 months +474.1% +5.0% -81.0% TXG
Better 5-year returnAnnualised price return, 5 years -13.9%/yr -5.3%/yr -56.8%/yr DHR
Less volatileAnnualised volatility, 1 year 73.9% 30.6% 183.1% DHR
Higher overall scoreMean of the five percentile scores vs peers 61/100 59/100 25/100 TXG

Percentile Scorecard

TXGDHRSGMOQ

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisTXGDHRSGMOQ
Valuation 43 #130 of 227 67 #76 of 227 9 #571 of 625
Growth 66 #76 of 219 21 #174 of 219 43 #346 of 602
Profitability 63 #77 of 206 88 #25 of 206 44 #311 of 551
Financial Health 68 #78 of 238 46 #129 of 238 4 #628 of 656
Shareholder Returns 68 #44 of 134 75 #34 of 134 –
Overall 61 59 25
  • TXG ranked among 247 companies in Medical Devices and Diagnostics
  • DHR ranked among 247 companies in Medical Devices and Diagnostics
  • SGMOQ ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodTXGDHRSGMOQSPY
1 month -9.0%+3.3%-14.3% -0.2%
3 months +65.8%+16.6%+100.0% +3.9%
6 months +265.1%+29.7%-42.9% +8.2%
Year to date +378.4%+1.4%-71.4% +12.9%
1 year +474.1%+5.0%-81.0% +12.3%
3 years +114.3%+23.5%-74.5% +87.4%
3 years, per year +28.9%+7.3%-36.6% +23.3%
5 years -52.6%-23.8%-98.5% +67.9%
5 years, per year -13.9%-5.3%-56.8% +10.9%
10 years —+196.3%-96.8% +261.1%
10 years, per year —+11.5%-29.1% +13.7%

Risk

MeasureTXGDHRSGMOQSPY
Volatility, 1Y 73.9%30.6%183.1% 12.7%
Downside volatility, 1Y 66.1%31.6%254.9% 12.7%
Beta vs S&P 500, 1Y 2.220.452.09 1.00
Return / volatility, 1Y 6.410.16-0.44 0.97
Max drawdown, 5Y -96.1%-50.8%-99.6% -25.4%
From 52-week high -20.2%-4.1%-81.0% -1.2%
52-week high $97.74$242.05$0.63 $779.14
52-week low $12.44$161.91$0.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleTXGDHRSGMOQ
P/E now vs peer median -135.0xmedian 29.6x 40.9xmedian 29.6x -0.3xmedian 17.2x
P/S now vs peer median 16.5xmedian 2.9x 6.5xmedian 2.9x 0.9xmedian 9.0x
EV/EBITDA now vs peer median -227.8xmedian 17.4x 24.2xmedian 17.4x -0.1xmedian 16.3x
P/FCF now vs peer median 83.7xmedian 22.3x 29.8xmedian 22.3x -0.3xmedian 18.7x
P/B now vs peer median 12.3xmedian 2.3x 3.1xmedian 2.3x -2.4xmedian 2.2x
PEG now vs peer median -5.03median 1.04 -3.26median 1.04 -0.01median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsTXGDHRSGMOQ
Revenue $616.91M $25.11B $39.55M
Gross profit $432.03M $14.69B –
Operating income -$88.38M $5.13B -$121.24M
Net income -$75.13M $4.00B -$122.93M
Free cash flow $121.44M $5.47B -$97.29M
R&D $226.80M $1.62B $112.67M
EPS (diluted) $-0.58 $5.66 $-0.44
Cash & equivalents – $4.35B $20.95M
Total debt – $26.56B –
Shares (diluted) 129.98M 707.60M 280.20M
Enterprise value $9.97B $146.95B -$80.48M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricTXGDHRSGMOQ
P/E -135.0x 40.9x -0.3x
P/FCF 83.7x 29.8x -0.3x
P/Operating cash flow 80.0x 24.6x -0.3x
P/S 16.5x 6.5x 0.9x
P/B 12.3x 3.1x -2.4x
P/Tangible book 13.3x 5.2x -2.4x
EV/EBITDA -227.8x 24.2x -0.1x
EV/EBIT -114.4x 36.1x -0.1x
EV/Revenue 16.4x 7.4x 0.3x
EV/FCF 83.3x 33.9x -0.1x
EV/Operating cash flow 79.6x 27.9x -0.1x
PEG (3Y EPS CAGR) -5.03 -3.26 -0.01

Growth

14 metrics
MetricTXGDHRSGMOQ
Revenue growth (1Y) -4.3% 4.6% -31.6%
Revenue CAGR (3Y) 2.8% -0.5% -29.2%
Gross profit growth (1Y) -3.5% 2.6% –
Gross profit CAGR (3Y) 1.1% -0.9% –
Operating income growth (1Y) 12.1% 16.1% -16.6%
Operating income CAGR (3Y) 20.9% -7.1% 15.5%
Net income growth (1Y) 11.2% 17.3% -25.5%
Net income CAGR (3Y) 24.2% -14.3% 13.9%
EPS growth (1Y) 14.9% 19.2% 10.8%
EPS CAGR (3Y) 26.8% -12.5% 29.4%
Operating cash flow growth (1Y) 89.8% 7.6% -44.8%
Operating cash flow CAGR (3Y) 135.5% -7.6% 24.2%
Free cash flow growth (1Y) 113.5% 12.4% -44.3%
Free cash flow CAGR (3Y) 44.7% -9.0% 26.4%

Profitability

14 metrics
MetricTXGDHRSGMOQ
Gross margin 70.0% 58.5% –
EBITDA margin -7.2% 30.5% -296.4%
Operating margin -14.3% 20.4% -306.5%
Pretax margin -12.1% 19.0% -312.2%
Net margin -12.2% 15.9% -310.8%
FCF margin 19.7% 21.8% -246.0%
Operating cash flow margin 20.6% 26.4% -245.8%
Return on equity -9.2% 7.6% –
Return on assets -7.3% 4.5% -165.7%
Return on invested capital – 5.7% –
Return on capital employed -9.8% 6.4% -382.1%
Asset turnover 0.6x 0.3x 0.5x
Cash conversion (OCF / net income) -1.7x 1.7x 0.8x
Stock comp / revenue 16.0% 1.2% 23.0%

Financial Health

11 metrics
MetricTXGDHRSGMOQ
Debt / assets – 28.8% –
Debt / equity – 0.5x –
Net debt / EBITDA – 2.9x –
Debt / FCF – 4.9x –
Liabilities / assets 19.9% 43.1% 123.9%
Equity / assets 80.1% 56.9% -23.9%
Interest coverage – 17.6x –
Current ratio 5.7x 1.7x 0.8x
Quick ratio 0.8x 1.0x 0.5x
Cash ratio 0.4x 0.5x 0.5x
Altman Z-score 28.69 3.72 -44.03

Shareholder Returns

7 metrics
MetricTXGDHRSGMOQ
Dividend yield – 0.7% –
Net buyback yield -0.1% 1.8% -220.1%
Shareholder yield -0.1% 2.4% -220.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusTXGDHRSGMOQ
Forward P/E – 25.5xFY2026 –
EPS, next fiscal year $-0.79FY2026 $9.11FY2026 $-0.31FY2026
EPS growth, next FY – +16.8%FY2026 –
EPS growth, the year after – +8.0% –
Revenue, next fiscal year $580.42MFY2026 $27.01BFY2026 $9.62MFY2026
Revenue growth, next FY -9.7%FY2026 +9.9%FY2026 -75.7%FY2026
Revenue growth, the year after +24.6% -1.9% +606.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersTXGDHRSGMOQ
Held by institutions 100.0% 81.9% –
Institutions holding 389 2,116 –
Change in shares held, QoQ +2.4% +1.1% –
Institutions buying 197 838 –
Institutions selling 137 1,015 –
Buyers to sellers 1.44 0.83 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

TXGDHRSGMOQ
TXG 1.00 0.33 0.13
DHR 0.33 1.00 0.02
SGMOQ 0.13 0.02 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, TXG, DHR and SGMOQ?

Danaher (DHR) is the largest by market capitalisation: 10x Genomics (TXG) $10.16B, Danaher (DHR) $163.13B, Sangamo Therapeutics (SGMOQ) $33.62M.

Which company is growing faster?

Danaher (DHR) grew revenue fastest over the trailing twelve months: 10x Genomics (TXG) -4.3%, Danaher (DHR) +4.6%, Sangamo Therapeutics (SGMOQ) -31.6%.

Which company is more profitable?

Danaher (DHR) has the highest net margin (10x Genomics (TXG) -12.2%, Danaher (DHR) 15.9%, Sangamo Therapeutics (SGMOQ) -310.8%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: 10x Genomics (TXG) +474.1%, Danaher (DHR) +5.0%, Sangamo Therapeutics (SGMOQ) -81.0%. Over five years, Danaher (DHR) compounded fastest (10x Genomics (TXG) -13.9%/yr, Danaher (DHR) -5.3%/yr, Sangamo Therapeutics (SGMOQ) -56.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Danaher (DHR) 0.65%. 10x Genomics (TXG) and Sangamo Therapeutics (SGMOQ) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Danaher (DHR) has been the steadiest (10x Genomics (TXG) 73.9%, Danaher (DHR) 30.6%, Sangamo Therapeutics (SGMOQ) 183.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, TXG, DHR and SGMOQ?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Danaher (DHR) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.