SRPT vs SLBT vs NTLA Stock Comparison

Sarepta Therapeutics, SL Science Holding and Intellia Therapeutics Prices as of Oct 28, 2026 Peers: Industry group
SLBT SL Science Holding Ltd
$1.21 -37.3% 1M -88.3% 1Y
Market cap
$2.64B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

7 decided of 12

Intellia Therapeutics leads on 3 of the 12 questions below (Intellia Therapeutics 3, Sarepta Therapeutics 3, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSRPTSLBTNTLALeader
Larger companyMarket capitalisation $2.04B $2.64B $1.87B SLBT
Cheaper on earningsLower P/E, profitable companies only -17.4x — -4.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 6.7x — — –
Faster revenue growthRevenue growth, trailing twelve months -20.4% — +12.6% NTLA
More profitableNet margin, trailing twelve months -5.9% — -672.2% SRPT
Better return on capitalReturn on invested capital -6.1% — — –
Less leveragedLower net debt / EBITDA -0.6x — — –
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months -20.2% -88.3% -4.6% NTLA
Better 5-year returnAnnualised price return, 5 years -24.6%/yr — -36.9%/yr SRPT
Less volatileAnnualised volatility, 1 year 81.1% 175.5% 80.0% NTLA
Higher overall scoreMean of the five percentile scores vs peers 67/100 — 50/100 SRPT

Percentile Scorecard

SRPTSLBTNTLA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSRPTSLBTNTLA
Valuation 96 #25 of 625 11 #556 of 625 34 #412 of 625
Growth 64 #217 of 602 – 64 #220 of 602
Profitability 79 #114 of 549 – 39 #338 of 549
Financial Health 33 #436 of 654 58 #276 of 654 72 #182 of 654
Shareholder Returns 61 #145 of 367 – 40 #220 of 367
Overall 67 – 50
  • SRPT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSRPTSLBTNTLASPY
1 month +2.8%-37.3%+16.6% +0.9%
3 months +24.4%-53.5%+23.3% +5.9%
6 months -6.5%-87.9%+7.1% +8.5%
Year to date -10.2%-88.5%+48.2% +13.3%
1 year -20.2%-88.3%-4.6% +12.4%
3 years -81.9%—-42.5% +88.1%
3 years, per year -43.5%—-16.8% +23.5%
5 years -75.6%—-90.0% +68.2%
5 years, per year -24.6%—-36.9% +11.0%
10 years -52.8%—+2.8% +263.4%
10 years, per year -7.2%—+0.3% +13.8%

Risk

MeasureSRPTSLBTNTLASPY
Volatility, 1Y 81.1%175.5%80.0% 12.7%
Downside volatility, 1Y 85.9%170.6%82.2% 12.7%
Beta vs S&P 500, 1Y 2.080.232.46 1.00
Return / volatility, 1Y -0.25-0.50-0.06 0.98
Max drawdown, 5Y -92.7%-91.0%-95.5% -25.4%
From 52-week high -21.0%-90.6%-25.3% -0.9%
52-week high $24.45$12.81$17.84 $779.14
52-week low $14.86$1.15$8.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSRPTSLBTNTLA
P/E now vs peer median -17.4xmedian 17.4x —median 17.4x -4.4xmedian 17.4x
P/S now vs peer median 1.0xmedian 9.1x —median 9.1x 31.3xmedian 9.1x
EV/EBITDA now vs peer median -21.3xmedian 17.1x —median 17.1x -3.4xmedian 17.1x
P/FCF now vs peer median 24.9xmedian 19.0x -1,406xmedian 19.0x -5.3xmedian 19.0x
P/B now vs peer median 1.3xmedian 2.2x 378.4xmedian 2.2x 2.6xmedian 2.2x
PEG now vs peer median -0.33median 0.34 —median 0.34 -0.27median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSRPTSLBTNTLA
Revenue $1.97B – $59.51M
Gross profit $1.17B – –
Operating income -$143.25M – -$423.48M
Net income -$136.73M – -$399.98M
Free cash flow $81.85M – -$348.69M
R&D $789.44M – $346.73M
EPS (diluted) $-1.11 – $-3.00
Cash & equivalents $571.15M $8.31M $106.13M
Total debt $847.62M – –
Shares (diluted) 105.43M – 133.48M
Enterprise value -$1.19B $2.62B $90.37M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSRPTSLBTNTLA
P/E -17.4x – -4.4x
P/FCF 24.9x -1,406x -5.3x
P/Operating cash flow 18.4x – -5.4x
P/S 1.0x – 31.3x
P/B 1.3x 378.4x 2.6x
P/Tangible book 1.4x 378.4x 2.6x
EV/EBITDA -21.3x – -3.4x
EV/EBIT -14.7x – -3.4x
EV/Revenue 1.1x – 24.0x
EV/FCF 25.7x – -4.1x
EV/Operating cash flow 18.9x – -4.1x
PEG (3Y EPS CAGR) -0.33 – -0.27

Growth

14 metrics
MetricSRPTSLBTNTLA
Revenue growth (1Y) -20.4% – 12.6%
Revenue CAGR (3Y) 25.3% – 3.9%
Gross profit growth (1Y) -40.7% – –
Gross profit CAGR (3Y) 10.6% – –
Operating income growth (1Y) -15,270% – 17.3%
Operating income CAGR (3Y) 34.5% – 2.7%
Net income growth (1Y) -135.9% – 16.7%
Net income CAGR (3Y) 46.8% – 4.1%
EPS growth (1Y) -215.7% – 35.3%
EPS CAGR (3Y) 52.3% – 16.5%
Operating cash flow growth (1Y) 136.9% – 17.2%
Operating cash flow CAGR (3Y) 30.6% – 2.0%
Free cash flow growth (1Y) 118.1% – 17.3%
Free cash flow CAGR (3Y) 29.1% – 3.2%

Profitability

14 metrics
MetricSRPTSLBTNTLA
Gross margin 59.1% – –
EBITDA margin -5.0% – -696.4%
Operating margin -7.3% – -711.7%
Pretax margin -6.6% – -671.0%
Net margin -5.9% – -672.2%
FCF margin 4.1% – -586.0%
Operating cash flow margin 5.6% – -582.5%
Return on equity -9.0% – -59.2%
Return on assets -4.3% – -49.4%
Return on invested capital -6.1% – –
Return on capital employed -5.3% – -58.1%
Asset turnover 0.6x – 0.1x
Cash conversion (OCF / net income) -0.8x – 0.9x
Stock comp / revenue 6.3% – 114.1%

Financial Health

11 metrics
MetricSRPTSLBTNTLA
Debt / assets 26.6% – –
Debt / equity 0.6x – –
Net debt / EBITDA -0.6x – –
Debt / FCF 10.4x – –
Liabilities / assets 52.1% 21.8% 15.1%
Equity / assets 47.9% 78.2% 84.9%
Interest coverage – – –
Current ratio 4.4x 4.4x 6.6x
Quick ratio 2.4x 4.3x 5.6x
Cash ratio 1.6x 4.3x 5.5x
Altman Z-score -0.14 – 3.15

Shareholder Returns

7 metrics
MetricSRPTSLBTNTLA
Dividend yield – – –
Net buyback yield -1.1% – -7.1%
Shareholder yield -1.1% 0.0% -7.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSRPTSLBTNTLA
Forward P/E 6.7xFY2026 – –
EPS, next fiscal year $2.88FY2026 – $-3.38FY2026
EPS growth, the year after -88.5% – –
Revenue, next fiscal year $1.76BFY2026 – $48.94MFY2026
Revenue growth, next FY -20.1%FY2026 – -27.7%FY2026
Revenue growth, the year after -21.5% – +158.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSRPTSLBTNTLA
Held by institutions 100.0% – 100.0%
Institutions holding 324 – 329
Change in shares held, QoQ +4.5% – +30.5%
Institutions buying 148 – 195
Institutions selling 115 – 78
Buyers to sellers 1.29 – 2.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SRPTSLBTNTLA
SRPT 1.00 0.00 0.33
SLBT 0.00 1.00 -0.09
NTLA 0.33 -0.09 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SRPT, SLBT and NTLA?

SL Science Holding (SLBT) is the largest by market capitalisation: Sarepta Therapeutics (SRPT) $2.04B, SL Science Holding (SLBT) $2.64B, Intellia Therapeutics (NTLA) $1.87B.

Which company is growing faster?

Intellia Therapeutics (NTLA) grew revenue fastest over the trailing twelve months: Sarepta Therapeutics (SRPT) -20.4%, Intellia Therapeutics (NTLA) +12.6%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Sarepta Therapeutics (SRPT) -5.9%, Intellia Therapeutics (NTLA) -672.2%).

Which stock has performed better?

Over the past year Intellia Therapeutics (NTLA) returned the most: Sarepta Therapeutics (SRPT) -20.2%, SL Science Holding (SLBT) -88.3%, Intellia Therapeutics (NTLA) -4.6%. Over five years, Sarepta Therapeutics (SRPT) compounded fastest (Sarepta Therapeutics (SRPT) -24.6%/yr, Intellia Therapeutics (NTLA) -36.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Intellia Therapeutics (NTLA) has been the steadiest (Sarepta Therapeutics (SRPT) 81.1%, SL Science Holding (SLBT) 175.5%, Intellia Therapeutics (NTLA) 80.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SRPT, SLBT and NTLA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intellia Therapeutics (NTLA) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.