SLDB vs SLBT vs PGEN Stock Comparison

Solid Biosciences, SL Science Holding and Precigen Prices as of Oct 27, 2026 Peers: Industry group
SLBT SL Science Holding Ltd
$1.19 -24.2% 1M -88.5% 1Y
Market cap
$2.70B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
PGEN Precigen, Inc.
$6.15 -20.6% 1M +43.0% 1Y
Market cap
$2.22B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

5 decided of 12

Precigen leads on 4 of the 12 questions below (Precigen 4, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLDBSLBTPGENLeader
Larger companyMarket capitalisation $901.65M $2.70B $2.22B SLBT
Cheaper on earningsLower P/E, profitable companies only -4.4x — -6.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 36.2x –
Faster revenue growthRevenue growth, trailing twelve months — — +1,875.0% –
More profitableNet margin, trailing twelve months — — -392.8% –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — -1.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +4.9% -88.5% +43.0% PGEN
Better 5-year returnAnnualised price return, 5 years -26.0%/yr — +4.4%/yr PGEN
Less volatileAnnualised volatility, 1 year 78.4% 175.4% 77.9% PGEN
Higher overall scoreMean of the five percentile scores vs peers 42/100 — 55/100 PGEN

Percentile Scorecard

SLDBSLBTPGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLDBSLBTPGEN
Valuation 34 #413 of 625 11 #555 of 625 59 #258 of 625
Growth 19 #488 of 602 – 49 #310 of 602
Profitability 50 #276 of 551 – 59 #227 of 551
Financial Health 88 #78 of 656 58 #279 of 656 27 #482 of 656
Shareholder Returns 18 #300 of 365 – 83 #63 of 365
Overall 42 – 55
  • SLDB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLDBSLBTPGENSPY
1 month -15.1%-24.2%-20.6% -0.2%
3 months -22.3%-56.7%+11.2% +3.9%
6 months -16.9%-84.9%+53.0% +8.2%
Year to date +9.8%-88.7%+47.1% +12.9%
1 year +4.9%-88.5%+43.0% +12.3%
3 years +227.5%—+508.9% +87.4%
3 years, per year +48.5%—+82.7% +23.3%
5 years -77.8%—+24.0% +67.9%
5 years, per year -26.0%—+4.4% +10.9%
10 years ——-76.2% +261.1%
10 years, per year ——-13.4% +13.7%

Risk

MeasureSLDBSLBTPGENSPY
Volatility, 1Y 78.4%175.4%77.9% 12.7%
Downside volatility, 1Y 77.0%170.6%69.4% 12.7%
Beta vs S&P 500, 1Y 2.120.231.43 1.00
Return / volatility, 1Y 0.06-0.500.55 0.97
Max drawdown, 5Y -94.9%-91.0%-87.8% -25.4%
From 52-week high -44.5%-90.7%-28.2% -1.2%
52-week high $11.15$12.81$8.56 $779.14
52-week low $3.93$1.15$3.10 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLDBSLBTPGEN
P/E now vs peer median -4.3xmedian 17.2x —median 17.2x -6.5xmedian 17.2x
P/S now vs peer median —median 9.0x —median 9.0x 25.7xmedian 9.0x
EV/EBITDA now vs peer median -2.4xmedian 16.3x —median 16.3x -65.8xmedian 16.3x
P/FCF now vs peer median -4.7xmedian 18.7x -1,382xmedian 18.7x -19.1xmedian 18.7x
P/B now vs peer median 2.4xmedian 2.2x 372.2xmedian 2.2x 50.5xmedian 2.2x
PEG now vs peer median -0.13median 0.33 —median 0.33 0.05median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLDBSLBTPGEN
Revenue – – $85.72M
Gross profit – – $77.72M
Operating income -$212.15M – -$39.50M
Net income -$207.10M – -$157.71M
Free cash flow -$187.82M – -$115.22M
R&D $167.40M – $32.29M
EPS (diluted) $-1.44 – $-0.81
Cash & equivalents $159.39M $8.31M $16.33M
Total debt – – $93.88M
Shares (diluted) 143.69M – 413.69M
Enterprise value -$280.70M $2.69B $1.90B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLDBSLBTPGEN
P/E -4.3x – -6.5x
P/FCF -4.7x -1,382x -19.1x
P/Operating cash flow -4.8x – -19.3x
P/S – – 25.7x
P/B 2.4x 372.2x 50.5x
P/Tangible book 2.4x 372.2x 53.7x
EV/EBITDA -2.4x – -65.8x
EV/EBIT -2.4x – -57.2x
EV/Revenue – – 26.3x
EV/FCF -2.7x – -19.6x
EV/Operating cash flow -2.7x – -19.8x
PEG (3Y EPS CAGR) -0.13 – 0.05

Growth

14 metrics
MetricSLDBSLBTPGEN
Revenue growth (1Y) – – 1,875%
Revenue CAGR (3Y) – – 57.1%
Gross profit growth (1Y) – – 259,173%
Gross profit CAGR (3Y) – – 69.2%
Operating income growth (1Y) -35.3% – 62.1%
Operating income CAGR (3Y) -22.8% – 18.9%
Net income growth (1Y) -34.4% – -26.7%
Net income CAGR (3Y) -31.9% – -108.9%
EPS growth (1Y) 11.9% – -93.8%
EPS CAGR (3Y) 32.0% – -123.2%
Operating cash flow growth (1Y) -52.4% – -72.3%
Operating cash flow CAGR (3Y) -19.2% – -15.9%
Free cash flow growth (1Y) -52.3% – -65.1%
Free cash flow CAGR (3Y) -18.4% – -15.3%

Profitability

14 metrics
MetricSLDBSLBTPGEN
Gross margin – – 90.7%
EBITDA margin – – -40.0%
Operating margin – – -46.1%
Pretax margin – – -184.0%
Net margin – – -392.8%
FCF margin – – -134.4%
Operating cash flow margin – – -133.2%
Return on equity -55.4% – -494.3%
Return on assets -49.1% – -102.1%
Return on invested capital – – –
Return on capital employed -54.0% – -31.6%
Asset turnover – – 0.6x
Cash conversion (OCF / net income) 0.9x – 0.7x
Stock comp / revenue – – 15.3%

Financial Health

11 metrics
MetricSLDBSLBTPGEN
Debt / assets – – 55.1%
Debt / equity – – 2.2x
Net debt / EBITDA – – -1.6x
Debt / FCF – – -0.8x
Liabilities / assets 11.1% 21.8% 74.4%
Equity / assets 88.9% 78.2% 25.6%
Interest coverage – – -4.1x
Current ratio 13.8x 4.4x 4.6x
Quick ratio 13.2x 4.3x 3.8x
Cash ratio 13.2x 4.3x 1.3x
Altman Z-score – – -8.25

Shareholder Returns

7 metrics
MetricSLDBSLBTPGEN
Dividend yield – – –
Net buyback yield -27.0% – -0.1%
Shareholder yield -27.0% 0.0% -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLDBSLBTPGEN
Forward P/E – – 36.2xFY2026
EPS, next fiscal year $-1.63FY2026 – $0.17FY2026
EPS growth, the year after – – +288.2%
Revenue, next fiscal year $0.00FY2026 – $249.17MFY2026
Revenue growth, next FY – – +2,474.1%FY2026
Revenue growth, the year after – – +82.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLDBSLBTPGEN
Held by institutions 79.7% – 39.2%
Institutions holding 157 – 210
Change in shares held, QoQ +18.9% – +4.9%
Institutions buying 101 – 123
Institutions selling 37 – 46
Buyers to sellers 2.73 – 2.67

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLDBSLBTPGEN
SLDB 1.00 -0.02 0.31
SLBT -0.02 1.00 0.00
PGEN 0.31 0.00 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLDB, SLBT and PGEN?

SL Science Holding (SLBT) is the largest by market capitalisation: Solid Biosciences (SLDB) $901.65M, SL Science Holding (SLBT) $2.70B, Precigen (PGEN) $2.22B.

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Solid Biosciences (SLDB) +4.9%, SL Science Holding (SLBT) -88.5%, Precigen (PGEN) +43.0%. Over five years, Precigen (PGEN) compounded fastest (Solid Biosciences (SLDB) -26.0%/yr, Precigen (PGEN) +4.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Precigen (PGEN) has been the steadiest (Solid Biosciences (SLDB) 78.4%, SL Science Holding (SLBT) 175.4%, Precigen (PGEN) 77.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLDB, SLBT and PGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.