SLDB vs LEGN vs SRPT Stock Comparison

Solid Biosciences, Legend Biotech and Sarepta Therapeutics Prices as of Oct 27, 2026 Peers: Industry group
SLDB Solid Biosciences Inc.
$6.19 -15.1% 1M +4.9% 1Y
Market cap
$926.07M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
LEGN Legend Biotech Corp
$21.56 +12.8% 1M -32.9% 1Y
Market cap
$4.13B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
6 wins

Head to Head

9 decided of 12

Legend Biotech leads on 6 of the 12 questions below (Legend Biotech 6, Sarepta Therapeutics 2, Solid Biosciences 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLDBLEGNSRPTLeader
Larger companyMarket capitalisation $926.07M $4.13B $2.02B LEGN
Cheaper on earningsLower P/E, profitable companies only -4.5x -45.1x -17.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.6x –
Faster revenue growthRevenue growth, trailing twelve months — +59.5% -20.4% LEGN
More profitableNet margin, trailing twelve months — -7.2% -5.9% SRPT
Better return on capitalReturn on invested capital — -4.2% -6.1% LEGN
Less leveragedLower net debt / EBITDA — 28.0x -0.6x SRPT
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +4.9% -32.9% -19.6% SLDB
Better 5-year returnAnnualised price return, 5 years -26.0%/yr -15.9%/yr -24.9%/yr LEGN
Less volatileAnnualised volatility, 1 year 78.4% 72.2% 81.2% LEGN
Higher overall scoreMean of the five percentile scores vs peers 42/100 72/100 67/100 LEGN

Percentile Scorecard

SLDBLEGNSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLDBLEGNSRPT
Valuation 34 #413 of 625 89 #70 of 625 96 #25 of 625
Growth 19 #488 of 602 96 #23 of 602 64 #218 of 602
Profitability 50 #276 of 551 80 #112 of 551 80 #114 of 551
Financial Health 88 #78 of 656 54 #305 of 656 34 #435 of 656
Shareholder Returns 18 #300 of 365 43 #209 of 365 60 #145 of 365
Overall 42 72 67
  • SLDB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLDBLEGNSRPTSPY
1 month -15.1%+12.8%+1.2% -0.2%
3 months -22.3%+13.2%+22.4% +3.9%
6 months -16.9%-8.5%-10.3% +8.2%
Year to date +9.8%-0.8%-12.2% +12.9%
1 year +4.9%-32.9%-19.6% +12.3%
3 years +227.5%-66.1%-82.3% +87.4%
3 years, per year +48.5%-30.3%-43.9% +23.3%
5 years -77.8%-57.9%-76.2% +67.9%
5 years, per year -26.0%-15.9%-24.9% +10.9%
10 years ——-53.7% +261.1%
10 years, per year ——-7.4% +13.7%

Risk

MeasureSLDBLEGNSRPTSPY
Volatility, 1Y 78.4%72.2%81.2% 12.7%
Downside volatility, 1Y 77.0%62.7%85.9% 12.7%
Beta vs S&P 500, 1Y 2.120.432.08 1.00
Return / volatility, 1Y 0.06-0.46-0.24 0.97
Max drawdown, 5Y -94.9%-78.2%-92.7% -25.4%
From 52-week high -44.5%-40.6%-22.7% -1.2%
52-week high $11.15$36.28$24.45 $779.14
52-week low $3.93$16.65$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLDBLEGNSRPT
P/E now vs peer median -4.3xmedian 17.2x -43.3xmedian 17.2x -17.0xmedian 17.2x
P/S now vs peer median —median 9.0x 3.1xmedian 9.0x 1.0xmedian 9.0x
EV/EBITDA now vs peer median -2.4xmedian 16.3x -187.6xmedian 16.3x -20.8xmedian 16.3x
P/FCF now vs peer median -4.7xmedian 18.7x -61.5xmedian 18.7x 24.4xmedian 18.7x
P/B now vs peer median 2.4xmedian 2.2x 3.2xmedian 2.2x 1.3xmedian 2.2x
PEG now vs peer median -0.13median 0.33 -0.92median 0.33 -0.33median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLDBLEGNSRPT
Revenue – $1.27B $1.97B
Gross profit – $727.10M $1.17B
Operating income -$212.15M -$55.25M -$143.25M
Net income -$207.10M -$80.39M -$136.73M
Free cash flow -$187.82M -$64.60M $81.85M
R&D $167.40M $396.15M $789.44M
EPS (diluted) $-1.44 $-0.50 $-1.11
Cash & equivalents $159.39M $672.90M $571.15M
Total debt – $1.06B $847.62M
Shares (diluted) 143.69M 184.32M 105.43M
Enterprise value -$256.28M $1.63B -$1.21B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLDBLEGNSRPT
P/E -4.3x -43.3x -17.0x
P/FCF -4.7x -61.5x 24.4x
P/Operating cash flow -4.8x -44.5x 18.0x
P/S – 3.1x 1.0x
P/B 2.4x 3.2x 1.3x
P/Tangible book 2.4x 3.2x 1.3x
EV/EBITDA -2.4x -187.6x -20.8x
EV/EBIT -2.4x -62.6x -14.3x
EV/Revenue – 2.7x 1.0x
EV/FCF -2.7x -53.5x 25.1x
EV/Operating cash flow -2.7x -38.7x 18.5x
PEG (3Y EPS CAGR) -0.13 -0.92 -0.33

Growth

14 metrics
MetricSLDBLEGNSRPT
Revenue growth (1Y) – 59.5% -20.4%
Revenue CAGR (3Y) – 97.6% 25.3%
Gross profit growth (1Y) – 42.4% -40.7%
Gross profit CAGR (3Y) – 147.5% 10.6%
Operating income growth (1Y) -35.3% 75.3% -15,270%
Operating income CAGR (3Y) -22.8% 49.1% 34.5%
Net income growth (1Y) -34.4% 75.3% -135.9%
Net income CAGR (3Y) -31.9% 46.7% 46.8%
EPS growth (1Y) 11.9% 72.0% -215.7%
EPS CAGR (3Y) 32.0% 47.0% 52.3%
Operating cash flow growth (1Y) -52.4% 67.5% 136.9%
Operating cash flow CAGR (3Y) -19.2% 37.1% 30.6%
Free cash flow growth (1Y) -52.3% 77.8% 118.1%
Free cash flow CAGR (3Y) -18.4% 44.5% 29.1%

Profitability

14 metrics
MetricSLDBLEGNSRPT
Gross margin – 57.2% 59.1%
EBITDA margin – -1.5% -5.0%
Operating margin – -4.3% -7.3%
Pretax margin – -4.4% -6.6%
Net margin – -7.2% -5.9%
FCF margin – -5.1% 4.1%
Operating cash flow margin – -7.0% 5.6%
Return on equity -55.4% -8.3% -9.0%
Return on assets -49.1% -5.5% -4.3%
Return on invested capital – -4.2% -6.1%
Return on capital employed -54.0% -4.3% -5.3%
Asset turnover – 0.8x 0.6x
Cash conversion (OCF / net income) 0.9x 1.1x -0.8x
Stock comp / revenue – 5.2% 6.3%

Financial Health

11 metrics
MetricSLDBLEGNSRPT
Debt / assets – 8.9% 26.6%
Debt / equity – 0.1x 0.6x
Net debt / EBITDA – 28.0x -0.6x
Debt / FCF – -2.4x 10.4x
Liabilities / assets 11.1% 29.8% 52.1%
Equity / assets 88.9% 70.2% 47.9%
Interest coverage – -4.8x –
Current ratio 13.8x 3.0x 4.4x
Quick ratio 13.2x 1.7x 2.4x
Cash ratio 13.2x 1.7x 1.6x
Altman Z-score – 6.74 -0.16

Shareholder Returns

7 metrics
MetricSLDBLEGNSRPT
Dividend yield – – –
Net buyback yield -27.0% -5.4% -1.1%
Shareholder yield -27.0% -5.4% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLDBLEGNSRPT
Forward P/E – – 6.6xFY2026
EPS, next fiscal year $-1.63FY2026 $-0.04FY2026 $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $0.00FY2026 $1.37BFY2026 $1.76BFY2026
Revenue growth, next FY – +32.9%FY2026 -20.1%FY2026
Revenue growth, the year after – +35.9% -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLDBLEGNSRPT
Held by institutions 79.7% 55.9% 100.0%
Institutions holding 157 218 324
Change in shares held, QoQ +18.9% +7.3% +4.5%
Institutions buying 101 117 148
Institutions selling 37 78 115
Buyers to sellers 2.73 1.50 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLDBLEGNSRPT
SLDB 1.00 0.02 0.46
LEGN 0.02 1.00 0.09
SRPT 0.46 0.09 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, SLDB, LEGN and SRPT?

Legend Biotech (LEGN) is the largest by market capitalisation: Solid Biosciences (SLDB) $926.07M, Legend Biotech (LEGN) $4.13B, Sarepta Therapeutics (SRPT) $2.02B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Legend Biotech (LEGN) +59.5%, Sarepta Therapeutics (SRPT) -20.4%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Legend Biotech (LEGN) -7.2%, Sarepta Therapeutics (SRPT) -5.9%). On return on invested capital, Legend Biotech (LEGN) leads (Legend Biotech (LEGN) -4.2%, Sarepta Therapeutics (SRPT) -6.1%).

Which stock has performed better?

Over the past year Solid Biosciences (SLDB) returned the most: Solid Biosciences (SLDB) +4.9%, Legend Biotech (LEGN) -32.9%, Sarepta Therapeutics (SRPT) -19.6%. Over five years, Legend Biotech (LEGN) compounded fastest (Solid Biosciences (SLDB) -26.0%/yr, Legend Biotech (LEGN) -15.9%/yr, Sarepta Therapeutics (SRPT) -24.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (Solid Biosciences (SLDB) 78.4%, Legend Biotech (LEGN) 72.2%, Sarepta Therapeutics (SRPT) 81.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLDB, LEGN and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.