SLBT vs SLDB vs SRPT Stock Comparison

SL Science Holding, Solid Biosciences and Sarepta Therapeutics Prices as of Oct 27, 2026 Peers: Industry group
SLBT SL Science Holding Ltd
$1.19 -24.2% 1M -88.5% 1Y
Market cap
$2.69B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
SLDB Solid Biosciences Inc.
$6.19 -15.1% 1M +4.9% 1Y
Market cap
$926.07M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

5 decided of 12

Solid Biosciences leads on 2 of the 12 questions below (Solid Biosciences 2, Sarepta Therapeutics 2, SL Science Holding 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTSLDBSRPTLeader
Larger companyMarket capitalisation $2.69B $926.07M $2.02B SLBT
Cheaper on earningsLower P/E, profitable companies only — -4.5x -17.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.6x –
Faster revenue growthRevenue growth, trailing twelve months — — -20.4% –
More profitableNet margin, trailing twelve months — — -5.9% –
Better return on capitalReturn on invested capital — — -6.1% –
Less leveragedLower net debt / EBITDA — — -0.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -88.5% +4.9% -19.6% SLDB
Better 5-year returnAnnualised price return, 5 years — -26.0%/yr -24.9%/yr SRPT
Less volatileAnnualised volatility, 1 year 175.4% 78.4% 81.2% SLDB
Higher overall scoreMean of the five percentile scores vs peers — 42/100 67/100 SRPT

Percentile Scorecard

SLBTSLDBSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTSLDBSRPT
Valuation 11 #555 of 625 34 #413 of 625 96 #25 of 625
Growth – 19 #488 of 602 64 #218 of 602
Profitability – 50 #276 of 551 80 #114 of 551
Financial Health 58 #279 of 656 88 #78 of 656 34 #435 of 656
Shareholder Returns – 18 #300 of 365 60 #145 of 365
Overall – 42 67
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLDB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTSLDBSRPTSPY
1 month -24.2%-15.1%+1.2% -0.2%
3 months -56.7%-22.3%+22.4% +3.9%
6 months -84.9%-16.9%-10.3% +8.2%
Year to date -88.7%+9.8%-12.2% +12.9%
1 year -88.5%+4.9%-19.6% +12.3%
3 years —+227.5%-82.3% +87.4%
3 years, per year —+48.5%-43.9% +23.3%
5 years —-77.8%-76.2% +67.9%
5 years, per year —-26.0%-24.9% +10.9%
10 years ——-53.7% +261.1%
10 years, per year ——-7.4% +13.7%

Risk

MeasureSLBTSLDBSRPTSPY
Volatility, 1Y 175.4%78.4%81.2% 12.7%
Downside volatility, 1Y 170.6%77.0%85.9% 12.7%
Beta vs S&P 500, 1Y 0.232.122.08 1.00
Return / volatility, 1Y -0.500.06-0.24 0.97
Max drawdown, 5Y -91.0%-94.9%-92.7% -25.4%
From 52-week high -90.7%-44.5%-22.7% -1.2%
52-week high $12.81$11.15$24.45 $779.14
52-week low $1.15$3.93$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTSLDBSRPT
P/E now vs peer median —median 17.2x -4.3xmedian 17.2x -17.0xmedian 17.2x
P/S now vs peer median —median 9.0x —median 9.0x 1.0xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x -2.4xmedian 16.3x -20.8xmedian 16.3x
P/FCF now vs peer median -1,382xmedian 18.7x -4.7xmedian 18.7x 24.4xmedian 18.7x
P/B now vs peer median 372.2xmedian 2.2x 2.4xmedian 2.2x 1.3xmedian 2.2x
PEG now vs peer median —median 0.33 -0.13median 0.33 -0.33median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTSLDBSRPT
Revenue – – $1.97B
Gross profit – – $1.17B
Operating income – -$212.15M -$143.25M
Net income – -$207.10M -$136.73M
Free cash flow – -$187.82M $81.85M
R&D – $167.40M $789.44M
EPS (diluted) – $-1.44 $-1.11
Cash & equivalents $8.31M $159.39M $571.15M
Total debt – – $847.62M
Shares (diluted) – 143.69M 105.43M
Enterprise value $2.68B -$256.28M -$1.21B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTSLDBSRPT
P/E – -4.3x -17.0x
P/FCF -1,382x -4.7x 24.4x
P/Operating cash flow – -4.8x 18.0x
P/S – – 1.0x
P/B 372.2x 2.4x 1.3x
P/Tangible book 372.2x 2.4x 1.3x
EV/EBITDA – -2.4x -20.8x
EV/EBIT – -2.4x -14.3x
EV/Revenue – – 1.0x
EV/FCF – -2.7x 25.1x
EV/Operating cash flow – -2.7x 18.5x
PEG (3Y EPS CAGR) – -0.13 -0.33

Growth

14 metrics
MetricSLBTSLDBSRPT
Revenue growth (1Y) – – -20.4%
Revenue CAGR (3Y) – – 25.3%
Gross profit growth (1Y) – – -40.7%
Gross profit CAGR (3Y) – – 10.6%
Operating income growth (1Y) – -35.3% -15,270%
Operating income CAGR (3Y) – -22.8% 34.5%
Net income growth (1Y) – -34.4% -135.9%
Net income CAGR (3Y) – -31.9% 46.8%
EPS growth (1Y) – 11.9% -215.7%
EPS CAGR (3Y) – 32.0% 52.3%
Operating cash flow growth (1Y) – -52.4% 136.9%
Operating cash flow CAGR (3Y) – -19.2% 30.6%
Free cash flow growth (1Y) – -52.3% 118.1%
Free cash flow CAGR (3Y) – -18.4% 29.1%

Profitability

14 metrics
MetricSLBTSLDBSRPT
Gross margin – – 59.1%
EBITDA margin – – -5.0%
Operating margin – – -7.3%
Pretax margin – – -6.6%
Net margin – – -5.9%
FCF margin – – 4.1%
Operating cash flow margin – – 5.6%
Return on equity – -55.4% -9.0%
Return on assets – -49.1% -4.3%
Return on invested capital – – -6.1%
Return on capital employed – -54.0% -5.3%
Asset turnover – – 0.6x
Cash conversion (OCF / net income) – 0.9x -0.8x
Stock comp / revenue – – 6.3%

Financial Health

11 metrics
MetricSLBTSLDBSRPT
Debt / assets – – 26.6%
Debt / equity – – 0.6x
Net debt / EBITDA – – -0.6x
Debt / FCF – – 10.4x
Liabilities / assets 21.8% 11.1% 52.1%
Equity / assets 78.2% 88.9% 47.9%
Interest coverage – – –
Current ratio 4.4x 13.8x 4.4x
Quick ratio 4.3x 13.2x 2.4x
Cash ratio 4.3x 13.2x 1.6x
Altman Z-score – – -0.16

Shareholder Returns

7 metrics
MetricSLBTSLDBSRPT
Dividend yield – – –
Net buyback yield – -27.0% -1.1%
Shareholder yield 0.0% -27.0% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTSLDBSRPT
Forward P/E – – 6.6xFY2026
EPS, next fiscal year – $-1.63FY2026 $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year – $0.00FY2026 $1.76BFY2026
Revenue growth, next FY – – -20.1%FY2026
Revenue growth, the year after – – -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTSLDBSRPT
Held by institutions – 79.7% 100.0%
Institutions holding – 157 324
Change in shares held, QoQ – +18.9% +4.5%
Institutions buying – 101 148
Institutions selling – 37 115
Buyers to sellers – 2.73 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTSLDBSRPT
SLBT 1.00 -0.02 0.00
SLDB -0.02 1.00 0.46
SRPT 0.00 0.46 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLBT, SLDB and SRPT?

SL Science Holding (SLBT) is the largest by market capitalisation: SL Science Holding (SLBT) $2.69B, Solid Biosciences (SLDB) $926.07M, Sarepta Therapeutics (SRPT) $2.02B.

Which stock has performed better?

Over the past year Solid Biosciences (SLDB) returned the most: SL Science Holding (SLBT) -88.5%, Solid Biosciences (SLDB) +4.9%, Sarepta Therapeutics (SRPT) -19.6%. Over five years, Sarepta Therapeutics (SRPT) compounded fastest (Solid Biosciences (SLDB) -26.0%/yr, Sarepta Therapeutics (SRPT) -24.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Solid Biosciences (SLDB) has been the steadiest (SL Science Holding (SLBT) 175.4%, Solid Biosciences (SLDB) 78.4%, Sarepta Therapeutics (SRPT) 81.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, SLDB and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Solid Biosciences (SLDB) leads on 2. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.