SLBT vs PGEN vs LEGN Stock Comparison

SL Science Holding, Precigen and Legend Biotech Prices as of Oct 29, 2026 Peers: Industry group
PGEN Precigen, Inc.
$6.64 -17.5% 1M +65.6% 1Y
Market cap
$2.38B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins
LEGN Legend Biotech Corp
$22.30 +18.5% 1M -30.6% 1Y
Market cap
$4.11B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

8 decided of 12

Legend Biotech leads on 4 of the 12 questions below (Legend Biotech 4, Precigen 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTPGENLEGNLeader
Larger companyMarket capitalisation $2.55B $2.38B $4.11B LEGN
Cheaper on earningsLower P/E, profitable companies only — -7.0x -44.8x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 39.1x — –
Faster revenue growthRevenue growth, trailing twelve months — +1,875.0% +59.5% PGEN
More profitableNet margin, trailing twelve months — -392.8% -7.2% LEGN
Better return on capitalReturn on invested capital — — -4.2% –
Less leveragedLower net debt / EBITDA — -1.6x 28.0x PGEN
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months -88.7% +65.6% -30.6% PGEN
Better 5-year returnAnnualised price return, 5 years — +6.6%/yr -15.7%/yr PGEN
Less volatileAnnualised volatility, 1 year 175.5% 78.1% 72.3% LEGN
Higher overall scoreMean of the five percentile scores vs peers — 55/100 73/100 LEGN

Percentile Scorecard

SLBTPGENLEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTPGENLEGN
Valuation 11 #556 of 624 60 #252 of 624 89 #70 of 624
Growth – 48 #314 of 601 97 #20 of 601
Profitability – 59 #224 of 541 80 #108 of 541
Financial Health 58 #271 of 647 27 #475 of 647 54 #299 of 647
Shareholder Returns – 82 #67 of 359 44 #201 of 359
Overall – 55 73
  • SLBT ranked among 671 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTPGENLEGNSPY
1 month -36.1%-17.5%+18.5% +0.7%
3 months -56.5%+11.8%+17.1% +3.7%
6 months -87.4%+59.6%-5.2% +7.1%
Year to date -88.9%+58.9%+2.6% +12.8%
1 year -88.7%+65.6%-30.6% +11.9%
3 years —+520.6%-66.0% +85.2%
3 years, per year —+83.8%-30.2% +22.8%
5 years —+37.5%-57.5% +67.6%
5 years, per year —+6.6%-15.7% +10.9%
10 years —-74.2%— +262.0%
10 years, per year —-12.7%— +13.7%

Risk

MeasureSLBTPGENLEGNSPY
Volatility, 1Y 175.5%78.1%72.3% 12.7%
Downside volatility, 1Y 170.0%69.2%62.7% 12.6%
Beta vs S&P 500, 1Y 0.241.410.44 1.00
Return / volatility, 1Y -0.510.84-0.42 0.94
Max drawdown, 5Y -91.0%-87.8%-78.2% -25.4%
From 52-week high -90.9%-22.4%-38.5% -1.2%
52-week high $12.81$8.56$36.28 $779.14
52-week low $1.15$3.10$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTPGENLEGN
P/E now vs peer median —median 17.8x -7.0xmedian 17.8x -44.8xmedian 17.8x
P/S now vs peer median —median 9.1x 27.7xmedian 9.1x 3.2xmedian 9.1x
EV/EBITDA now vs peer median —median 15.0x -70.9xmedian 15.0x -195.0xmedian 15.0x
P/FCF now vs peer median -1,359xmedian 21.7x -20.6xmedian 21.7x -63.6xmedian 21.7x
P/B now vs peer median 365.9xmedian 2.2x 54.6xmedian 2.2x 3.3xmedian 2.2x
PEG now vs peer median —median 0.35 0.06median 0.35 -0.95median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTPGENLEGN
Revenue – $85.72M $1.27B
Gross profit – $77.72M $727.10M
Operating income – -$39.50M -$55.25M
Net income – -$157.71M -$80.39M
Free cash flow – -$115.22M -$64.60M
R&D – $32.29M $396.15M
EPS (diluted) – $-0.81 $-0.50
Cash & equivalents $8.31M $16.33M $672.90M
Total debt – $93.88M $1.06B
Shares (diluted) – 413.69M 184.32M
Enterprise value $2.54B $2.06B $1.61B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTPGENLEGN
P/E – -7.0x -44.8x
P/FCF -1,359x -20.6x -63.6x
P/Operating cash flow – -20.8x -46.0x
P/S – 27.7x 3.2x
P/B 365.9x 54.6x 3.3x
P/Tangible book 365.9x 57.9x 3.3x
EV/EBITDA – -70.9x -195.0x
EV/EBIT – -61.6x -65.0x
EV/Revenue – 28.4x 2.8x
EV/FCF – -21.1x -55.6x
EV/Operating cash flow – -21.3x -40.2x
PEG (3Y EPS CAGR) – 0.06 -0.95

Growth

14 metrics
MetricSLBTPGENLEGN
Revenue growth (1Y) – 1,875% 59.5%
Revenue CAGR (3Y) – 57.1% 97.6%
Gross profit growth (1Y) – 259,173% 42.4%
Gross profit CAGR (3Y) – 69.2% 147.5%
Operating income growth (1Y) – 62.1% 75.3%
Operating income CAGR (3Y) – 18.9% 49.1%
Net income growth (1Y) – -26.7% 75.3%
Net income CAGR (3Y) – -108.9% 46.7%
EPS growth (1Y) – -93.8% 72.0%
EPS CAGR (3Y) – -123.2% 47.0%
Operating cash flow growth (1Y) – -72.3% 67.5%
Operating cash flow CAGR (3Y) – -15.9% 37.1%
Free cash flow growth (1Y) – -65.1% 77.8%
Free cash flow CAGR (3Y) – -15.3% 44.5%

Profitability

14 metrics
MetricSLBTPGENLEGN
Gross margin – 90.7% 57.2%
EBITDA margin – -40.0% -1.5%
Operating margin – -46.1% -4.3%
Pretax margin – -184.0% -4.4%
Net margin – -392.8% -7.2%
FCF margin – -134.4% -5.1%
Operating cash flow margin – -133.2% -7.0%
Return on equity – -494.3% -8.3%
Return on assets – -102.1% -5.5%
Return on invested capital – – -4.2%
Return on capital employed – -31.6% -4.3%
Asset turnover – 0.6x 0.8x
Cash conversion (OCF / net income) – 0.7x 1.1x
Stock comp / revenue – 15.3% 5.2%

Financial Health

11 metrics
MetricSLBTPGENLEGN
Debt / assets – 55.1% 8.9%
Debt / equity – 2.2x 0.1x
Net debt / EBITDA – -1.6x 28.0x
Debt / FCF – -0.8x -2.4x
Liabilities / assets 21.8% 74.4% 29.8%
Equity / assets 78.2% 25.6% 70.2%
Interest coverage – -4.1x -4.8x
Current ratio 4.4x 4.6x 3.0x
Quick ratio 4.3x 3.8x 1.7x
Cash ratio 4.3x 1.3x 1.7x
Altman Z-score – -7.41 6.90

Shareholder Returns

7 metrics
MetricSLBTPGENLEGN
Dividend yield – – –
Net buyback yield – -0.1% -5.2%
Shareholder yield 0.0% -0.1% -5.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTPGENLEGN
Forward P/E – 39.1xFY2026 –
EPS, next fiscal year – $0.17FY2026 $-0.04FY2026
EPS growth, the year after – +288.2% –
Revenue, next fiscal year – $249.17MFY2026 $1.37BFY2026
Revenue growth, next FY – +2,474.1%FY2026 +32.9%FY2026
Revenue growth, the year after – +82.3% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTPGENLEGN
Held by institutions – 39.2% 55.9%
Institutions holding – 211 218
Change in shares held, QoQ – +4.9% +7.3%
Institutions buying – 123 117
Institutions selling – 46 78
Buyers to sellers – 2.67 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTPGENLEGN
SLBT 1.00 0.00 -0.03
PGEN 0.00 1.00 0.06
LEGN -0.03 0.06 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLBT, PGEN and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: SL Science Holding (SLBT) $2.55B, Precigen (PGEN) $2.38B, Legend Biotech (LEGN) $4.11B.

Which company is growing faster?

Precigen (PGEN) grew revenue fastest over the trailing twelve months: Precigen (PGEN) +1,875.0%, Legend Biotech (LEGN) +59.5%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Precigen (PGEN) -392.8%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: SL Science Holding (SLBT) -88.7%, Precigen (PGEN) +65.6%, Legend Biotech (LEGN) -30.6%. Over five years, Precigen (PGEN) compounded fastest (Precigen (PGEN) +6.6%/yr, Legend Biotech (LEGN) -15.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (SL Science Holding (SLBT) 175.5%, Precigen (PGEN) 78.1%, Legend Biotech (LEGN) 72.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, PGEN and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.