SLBT vs LEGN vs NTLA Stock Comparison

SL Science Holding, Legend Biotech and Intellia Therapeutics Prices as of Oct 28, 2026 Peers: Industry group
LEGN Legend Biotech Corp
$22.53 +21.0% 1M -30.8% 1Y
Market cap
$4.11B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
6 wins

Head to Head

7 decided of 12

Legend Biotech leads on 6 of the 12 questions below (Legend Biotech 6, Intellia Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTLEGNNTLALeader
Larger companyMarket capitalisation $2.70B $4.11B $1.77B LEGN
Cheaper on earningsLower P/E, profitable companies only — -44.8x -4.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +59.5% +12.6% LEGN
More profitableNet margin, trailing twelve months — -7.2% -672.2% LEGN
Better return on capitalReturn on invested capital — -4.2% — –
Less leveragedLower net debt / EBITDA — 28.0x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -88.3% -30.8% -4.6% NTLA
Better 5-year returnAnnualised price return, 5 years — -15.6%/yr -36.9%/yr LEGN
Less volatileAnnualised volatility, 1 year 175.5% 72.3% 80.0% LEGN
Higher overall scoreMean of the five percentile scores vs peers — 73/100 50/100 LEGN

Percentile Scorecard

SLBTLEGNNTLA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTLEGNNTLA
Valuation 11 #556 of 625 89 #72 of 625 34 #412 of 625
Growth – 96 #23 of 602 64 #220 of 602
Profitability – 80 #109 of 549 39 #338 of 549
Financial Health 58 #276 of 654 54 #299 of 654 72 #182 of 654
Shareholder Returns – 44 #206 of 367 40 #220 of 367
Overall – 73 50
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NTLA ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTLEGNNTLASPY
1 month -37.3%+21.0%+16.6% +0.9%
3 months -53.5%+19.5%+23.3% +5.9%
6 months -87.9%-1.1%+7.1% +8.5%
Year to date -88.5%+3.6%+48.2% +13.3%
1 year -88.3%-30.8%-4.6% +12.4%
3 years —-64.6%-42.5% +88.1%
3 years, per year —-29.3%-16.8% +23.5%
5 years —-57.1%-90.0% +68.2%
5 years, per year —-15.6%-36.9% +11.0%
10 years ——+2.8% +263.4%
10 years, per year ——+0.3% +13.8%

Risk

MeasureSLBTLEGNNTLASPY
Volatility, 1Y 175.5%72.3%80.0% 12.7%
Downside volatility, 1Y 170.6%62.7%82.2% 12.7%
Beta vs S&P 500, 1Y 0.230.442.46 1.00
Return / volatility, 1Y -0.50-0.43-0.06 0.98
Max drawdown, 5Y -91.0%-78.2%-95.5% -25.4%
From 52-week high -90.6%-37.9%-25.3% -0.9%
52-week high $12.81$36.28$17.84 $779.14
52-week low $1.15$16.65$8.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTLEGNNTLA
P/E now vs peer median —median 17.4x -45.3xmedian 17.4x -4.4xmedian 17.4x
P/S now vs peer median —median 9.1x 3.3xmedian 9.1x 31.3xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x -197.3xmedian 17.1x -3.4xmedian 17.1x
P/FCF now vs peer median -1,406xmedian 19.0x -64.3xmedian 19.0x -5.3xmedian 19.0x
P/B now vs peer median 378.4xmedian 2.2x 3.4xmedian 2.2x 2.6xmedian 2.2x
PEG now vs peer median —median 0.34 -0.96median 0.34 -0.27median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTLEGNNTLA
Revenue – $1.27B $59.51M
Gross profit – $727.10M –
Operating income – -$55.25M -$423.48M
Net income – -$80.39M -$399.98M
Free cash flow – -$64.60M -$348.69M
R&D – $396.15M $346.73M
EPS (diluted) – $-0.50 $-3.00
Cash & equivalents $8.31M $672.90M $106.13M
Total debt – $1.06B –
Shares (diluted) – 184.32M 133.48M
Enterprise value $2.69B $1.61B -$1.39M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTLEGNNTLA
P/E – -45.3x -4.4x
P/FCF -1,406x -64.3x -5.3x
P/Operating cash flow – -46.5x -5.4x
P/S – 3.3x 31.3x
P/B 378.4x 3.4x 2.6x
P/Tangible book 378.4x 3.4x 2.6x
EV/EBITDA – -197.3x -3.4x
EV/EBIT – -65.8x -3.4x
EV/Revenue – 2.9x 24.0x
EV/FCF – -56.3x -4.1x
EV/Operating cash flow – -40.7x -4.1x
PEG (3Y EPS CAGR) – -0.96 -0.27

Growth

14 metrics
MetricSLBTLEGNNTLA
Revenue growth (1Y) – 59.5% 12.6%
Revenue CAGR (3Y) – 97.6% 3.9%
Gross profit growth (1Y) – 42.4% –
Gross profit CAGR (3Y) – 147.5% –
Operating income growth (1Y) – 75.3% 17.3%
Operating income CAGR (3Y) – 49.1% 2.7%
Net income growth (1Y) – 75.3% 16.7%
Net income CAGR (3Y) – 46.7% 4.1%
EPS growth (1Y) – 72.0% 35.3%
EPS CAGR (3Y) – 47.0% 16.5%
Operating cash flow growth (1Y) – 67.5% 17.2%
Operating cash flow CAGR (3Y) – 37.1% 2.0%
Free cash flow growth (1Y) – 77.8% 17.3%
Free cash flow CAGR (3Y) – 44.5% 3.2%

Profitability

14 metrics
MetricSLBTLEGNNTLA
Gross margin – 57.2% –
EBITDA margin – -1.5% -696.4%
Operating margin – -4.3% -711.7%
Pretax margin – -4.4% -671.0%
Net margin – -7.2% -672.2%
FCF margin – -5.1% -586.0%
Operating cash flow margin – -7.0% -582.5%
Return on equity – -8.3% -59.2%
Return on assets – -5.5% -49.4%
Return on invested capital – -4.2% –
Return on capital employed – -4.3% -58.1%
Asset turnover – 0.8x 0.1x
Cash conversion (OCF / net income) – 1.1x 0.9x
Stock comp / revenue – 5.2% 114.1%

Financial Health

11 metrics
MetricSLBTLEGNNTLA
Debt / assets – 8.9% –
Debt / equity – 0.1x –
Net debt / EBITDA – 28.0x –
Debt / FCF – -2.4x –
Liabilities / assets 21.8% 29.8% 15.1%
Equity / assets 78.2% 70.2% 84.9%
Interest coverage – -4.8x –
Current ratio 4.4x 3.0x 6.6x
Quick ratio 4.3x 1.7x 5.6x
Cash ratio 4.3x 1.7x 5.5x
Altman Z-score – 6.95 3.15

Shareholder Returns

7 metrics
MetricSLBTLEGNNTLA
Dividend yield – – –
Net buyback yield – -5.2% -7.1%
Shareholder yield 0.0% -5.2% -7.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTLEGNNTLA
EPS, next fiscal year – $-0.04FY2026 $-3.38FY2026
Revenue, next fiscal year – $1.37BFY2026 $48.94MFY2026
Revenue growth, next FY – +32.9%FY2026 -27.7%FY2026
Revenue growth, the year after – +35.9% +158.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTLEGNNTLA
Held by institutions – 55.9% 100.0%
Institutions holding – 218 329
Change in shares held, QoQ – +7.3% +30.5%
Institutions buying – 117 195
Institutions selling – 78 78
Buyers to sellers – 1.50 2.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTLEGNNTLA
SLBT 1.00 -0.03 -0.09
LEGN -0.03 1.00 0.08
NTLA -0.09 0.08 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLBT, LEGN and NTLA?

Legend Biotech (LEGN) is the largest by market capitalisation: SL Science Holding (SLBT) $2.70B, Legend Biotech (LEGN) $4.11B, Intellia Therapeutics (NTLA) $1.77B.

Which company is growing faster?

Legend Biotech (LEGN) grew revenue fastest over the trailing twelve months: Legend Biotech (LEGN) +59.5%, Intellia Therapeutics (NTLA) +12.6%.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Legend Biotech (LEGN) -7.2%, Intellia Therapeutics (NTLA) -672.2%).

Which stock has performed better?

Over the past year Intellia Therapeutics (NTLA) returned the most: SL Science Holding (SLBT) -88.3%, Legend Biotech (LEGN) -30.8%, Intellia Therapeutics (NTLA) -4.6%. Over five years, Legend Biotech (LEGN) compounded fastest (Legend Biotech (LEGN) -15.6%/yr, Intellia Therapeutics (NTLA) -36.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Legend Biotech (LEGN) has been the steadiest (SL Science Holding (SLBT) 175.5%, Legend Biotech (LEGN) 72.3%, Intellia Therapeutics (NTLA) 80.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, LEGN and NTLA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.