SLBT vs IOVA vs VCEL Stock Comparison

SL Science Holding, Iovance Biotherapeutics and Vericel Prices as of Oct 27, 2026 Peers: Industry group
VCEL Vericel Corp
$43.27 +9.0% 1M +18.6% 1Y
Market cap
$2.17B
P/E
89.4x
Revenue (TTM)
$306.30M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

7 decided of 12

Vericel leads on 4 of the 12 questions below (Vericel 4, Iovance Biotherapeutics 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTIOVAVCELLeader
Larger companyMarket capitalisation $2.70B $6.65B $2.17B IOVA
Cheaper on earningsLower P/E, profitable companies only — -23.0x 89.4x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 84.8x –
Faster revenue growthRevenue growth, trailing twelve months — +34.5% +23.0% IOVA
More profitableNet margin, trailing twelve months — -89.1% 7.9% VCEL
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -88.5% +531.2% +18.6% IOVA
Better 5-year returnAnnualised price return, 5 years — -10.4%/yr -3.3%/yr VCEL
Less volatileAnnualised volatility, 1 year 175.4% 99.2% 40.8% VCEL
Higher overall scoreMean of the five percentile scores vs peers — 64/100 81/100 VCEL

Percentile Scorecard

SLBTIOVAVCEL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTIOVAVCEL
Valuation 11 #555 of 625 67 #209 of 625 82 #116 of 625
Growth – 81 #114 of 602 94 #38 of 602
Profitability – 62 #210 of 551 88 #66 of 551
Financial Health 58 #279 of 656 64 #238 of 656 69 #207 of 656
Shareholder Returns – 44 #205 of 365 73 #99 of 365
Overall – 64 81
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • VCEL ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTIOVAVCELSPY
1 month -24.2%+32.5%+9.0% -0.2%
3 months -56.7%+210.2%-7.4% +3.9%
6 months -84.9%+331.4%+21.4% +8.2%
Year to date -88.7%+434.1%+20.2% +12.9%
1 year -88.5%+531.2%+18.6% +12.3%
3 years —+316.6%+31.8% +87.4%
3 years, per year —+61.0%+9.7% +23.3%
5 years —-42.3%-15.3% +67.9%
5 years, per year —-10.4%-3.3% +10.9%
10 years —+143.0%+1,781.3% +261.1%
10 years, per year —+9.3%+34.1% +13.7%

Risk

MeasureSLBTIOVAVCELSPY
Volatility, 1Y 175.4%99.2%40.8% 12.7%
Downside volatility, 1Y 170.6%71.2%40.1% 12.7%
Beta vs S&P 500, 1Y 0.231.280.74 1.00
Return / volatility, 1Y -0.505.360.46 0.97
Max drawdown, 5Y -91.0%-93.4%-65.4% -25.4%
From 52-week high -90.7%-1.9%-10.4% -1.2%
52-week high $12.81$14.86$48.31 $779.14
52-week low $1.15$1.81$29.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTIOVAVCEL
P/E now vs peer median —median 17.2x -22.7xmedian 17.2x 91.2xmedian 17.2x
P/S now vs peer median —median 9.0x 20.3xmedian 9.0x 7.2xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x -23.9xmedian 16.3x 65.4xmedian 16.3x
P/FCF now vs peer median -1,382xmedian 18.7x -22.3xmedian 18.7x 35.9xmedian 18.7x
P/B now vs peer median 372.2xmedian 2.2x 9.0xmedian 2.2x 6.0xmedian 2.2x
PEG now vs peer median —median 0.33 -0.76median 0.33 1.68median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTIOVAVCEL
Revenue – $324.97M $306.30M
Gross profit – $157.29M $228.38M
Operating income – -$301.31M $18.24M
Net income – -$289.51M $24.22M
Free cash flow – -$296.40M $61.66M
R&D – $267.72M $29.17M
EPS (diluted) – $-0.64 $0.46
Cash & equivalents $8.31M $110.80M $125.40M
Shares (diluted) – 450.19M 52.31M
Enterprise value $2.69B $5.44B $1.58B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTIOVAVCEL
P/E – -22.7x 91.2x
P/FCF -1,382x -22.3x 35.9x
P/Operating cash flow – -25.0x 31.8x
P/S – 20.3x 7.2x
P/B 372.2x 9.0x 6.0x
P/Tangible book 372.2x 14.0x 6.1x
EV/EBITDA – -23.9x 65.4x
EV/EBIT – -20.9x 112.5x
EV/Revenue – 19.4x 6.7x
EV/FCF – -21.3x 33.3x
EV/Operating cash flow – -23.9x 29.4x
PEG (3Y EPS CAGR) – -0.76 1.68

Growth

14 metrics
MetricSLBTIOVAVCEL
Revenue growth (1Y) – 34.5% 23.0%
Revenue CAGR (3Y) – 1,009% 19.8%
Gross profit growth (1Y) – 95.1% 24.8%
Gross profit CAGR (3Y) – – 23.9%
Operating income growth (1Y) – 26.6% 1,428%
Operating income CAGR (3Y) – 11.1% 47.8%
Net income growth (1Y) – 25.8% 240.8%
Net income CAGR (3Y) – 11.6% 56.6%
EPS growth (1Y) – 44.8% 228.1%
EPS CAGR (3Y) – 29.9% 54.3%
Operating cash flow growth (1Y) – 12.9% 47.5%
Operating cash flow CAGR (3Y) – 7.6% 33.7%
Free cash flow growth (1Y) – 8.4% 842.9%
Free cash flow CAGR (3Y) – 5.8% 43.2%

Profitability

14 metrics
MetricSLBTIOVAVCEL
Gross margin – 48.4% 74.6%
EBITDA margin – -81.4% 10.2%
Operating margin – -92.7% 6.0%
Pretax margin – -90.4% 8.2%
Net margin – -89.1% 7.9%
FCF margin – -91.2% 20.1%
Operating cash flow margin – -81.3% 22.7%
Return on equity – -39.7% 6.9%
Return on assets – -31.4% 5.1%
Return on invested capital – – –
Return on capital employed – -37.0% 4.1%
Asset turnover – 0.4x 0.6x
Cash conversion (OCF / net income) – 0.9x 2.9x
Stock comp / revenue – 14.4% 12.2%

Financial Health

11 metrics
MetricSLBTIOVAVCEL
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 21.8% 19.6% 26.4%
Equity / assets 78.2% 80.4% 73.6%
Interest coverage – – 28.5x
Current ratio 4.4x 4.3x 5.0x
Quick ratio 4.3x 3.7x 4.5x
Cash ratio 4.3x 2.8x 3.1x
Altman Z-score – 17.38 10.18

Shareholder Returns

7 metrics
MetricSLBTIOVAVCEL
Dividend yield – – –
Net buyback yield – -4.5% -0.3%
Shareholder yield 0.0% -4.5% -0.3%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTIOVAVCEL
Forward P/E – – 84.8xFY2026
EPS, next fiscal year – $-0.47FY2026 $0.51FY2026
EPS growth, next FY – – +59.4%FY2026
EPS growth, the year after – – +74.5%
Revenue, next fiscal year – $434.71MFY2026 $324.56MFY2026
Revenue growth, next FY – +65.0%FY2026 +17.5%FY2026
Revenue growth, the year after – +33.0% +16.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTIOVAVCEL
Held by institutions – 63.3% 100.0%
Institutions holding – 292 317
Change in shares held, QoQ – +6.5% +0.4%
Institutions buying – 174 187
Institutions selling – 66 98
Buyers to sellers – 2.64 1.91

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTIOVAVCEL
SLBT 1.00 0.01 0.03
IOVA 0.01 1.00 0.21
VCEL 0.03 0.21 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, SLBT, IOVA and VCEL?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: SL Science Holding (SLBT) $2.70B, Iovance Biotherapeutics (IOVA) $6.65B, Vericel (VCEL) $2.17B.

Which company is growing faster?

Iovance Biotherapeutics (IOVA) grew revenue fastest over the trailing twelve months: Iovance Biotherapeutics (IOVA) +34.5%, Vericel (VCEL) +23.0%.

Which company is more profitable?

Vericel (VCEL) has the highest net margin (Iovance Biotherapeutics (IOVA) -89.1%, Vericel (VCEL) 7.9%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: SL Science Holding (SLBT) -88.5%, Iovance Biotherapeutics (IOVA) +531.2%, Vericel (VCEL) +18.6%. Over five years, Vericel (VCEL) compounded fastest (Iovance Biotherapeutics (IOVA) -10.4%/yr, Vericel (VCEL) -3.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vericel (VCEL) has been the steadiest (SL Science Holding (SLBT) 175.4%, Iovance Biotherapeutics (IOVA) 99.2%, Vericel (VCEL) 40.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, IOVA and VCEL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vericel (VCEL) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.