SLBT vs IOVA vs BEAM Stock Comparison

SL Science Holding, Iovance Biotherapeutics and Beam Therapeutics Prices as of Oct 28, 2026 Peers: Industry group
BEAM Beam Therapeutics Inc.
$28.78 +18.8% 1M +8.9% 1Y
Market cap
$2.97B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins

Head to Head

7 decided of 12

Beam Therapeutics leads on 4 of the 12 questions below (Beam Therapeutics 4, Iovance Biotherapeutics 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSLBTIOVABEAMLeader
Larger companyMarket capitalisation $2.64B $6.71B $2.97B IOVA
Cheaper on earningsLower P/E, profitable companies only — -23.0x -35.1x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +34.5% +158.9% BEAM
More profitableNet margin, trailing twelve months — -89.1% -54.7% BEAM
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — 3.0x –
Higher dividend yieldTrailing dividend yield 0.00% — 0.00% –
Better 1-year returnPrice return, last 12 months -88.3% +576.3% +8.9% IOVA
Better 5-year returnAnnualised price return, 5 years — -9.4%/yr -20.2%/yr IOVA
Less volatileAnnualised volatility, 1 year 175.5% 99.0% 70.7% BEAM
Higher overall scoreMean of the five percentile scores vs peers — 64/100 69/100 BEAM

Percentile Scorecard

SLBTIOVABEAM

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSLBTIOVABEAM
Valuation 11 #556 of 625 67 #208 of 625 57 #272 of 625
Growth – 81 #113 of 602 77 #139 of 602
Profitability – 63 #206 of 549 64 #197 of 549
Financial Health 58 #276 of 654 64 #235 of 654 81 #123 of 654
Shareholder Returns – 45 #204 of 367 68 #119 of 367
Overall – 64 69
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSLBTIOVABEAMSPY
1 month -37.3%+34.8%+18.8% +0.9%
3 months -53.5%+224.8%+10.6% +5.9%
6 months -87.9%+347.4%-2.0% +8.5%
Year to date -88.5%+442.5%+3.8% +13.3%
1 year -88.3%+576.3%+8.9% +12.4%
3 years —+323.1%+54.6% +88.1%
3 years, per year —+61.8%+15.6% +23.5%
5 years —-39.1%-67.6% +68.2%
5 years, per year —-9.4%-20.2% +11.0%
10 years —+137.0%— +263.4%
10 years, per year —+9.0%— +13.8%

Risk

MeasureSLBTIOVABEAMSPY
Volatility, 1Y 175.5%99.0%70.7% 12.7%
Downside volatility, 1Y 170.6%71.1%64.0% 12.7%
Beta vs S&P 500, 1Y 0.231.292.09 1.00
Return / volatility, 1Y -0.505.820.13 0.98
Max drawdown, 5Y -91.0%-93.4%-85.3% -25.4%
From 52-week high -90.6%-0.3%-24.1% -0.9%
52-week high $12.81$14.86$37.92 $779.14
52-week low $1.15$1.81$20.60 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSLBTIOVABEAM
P/E now vs peer median —median 17.4x -23.0xmedian 17.4x -35.1xmedian 17.4x
P/S now vs peer median —median 9.1x 20.6xmedian 9.1x 19.0xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x -24.2xmedian 17.1x -5.4xmedian 17.1x
P/FCF now vs peer median -1,406xmedian 19.0x -22.6xmedian 19.0x -8.0xmedian 19.0x
P/B now vs peer median 378.4xmedian 2.2x 9.1xmedian 2.2x 2.8xmedian 2.2x
PEG now vs peer median —median 0.34 -0.77median 0.34 -0.83median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSLBTIOVABEAM
Revenue – $324.97M $156.04M
Gross profit – $157.29M –
Operating income – -$301.31M -$378.02M
Net income – -$289.51M -$86.52M
Free cash flow – -$296.40M -$372.77M
R&D – $267.72M $408.66M
EPS (diluted) – $-0.64 $-0.82
Cash & equivalents $8.31M $110.80M $219.83M
Total debt – – $100.26M
Shares (diluted) – 450.19M 104.33M
Enterprise value $2.62B $5.50B -$1.71B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSLBTIOVABEAM
P/E – -23.0x -35.1x
P/FCF -1,406x -22.6x -8.0x
P/Operating cash flow – -25.4x -8.3x
P/S – 20.6x 19.0x
P/B 378.4x 9.1x 2.8x
P/Tangible book 378.4x 14.2x 2.8x
EV/EBITDA – -24.2x -5.4x
EV/EBIT – -21.3x -5.1x
EV/Revenue – 19.7x 12.3x
EV/FCF – -21.6x -5.1x
EV/Operating cash flow – -24.3x -5.3x
PEG (3Y EPS CAGR) – -0.77 -0.83

Growth

14 metrics
MetricSLBTIOVABEAM
Revenue growth (1Y) – 34.5% 158.9%
Revenue CAGR (3Y) – 1,009% 24.9%
Gross profit growth (1Y) – 95.1% –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) – 26.6% 15.2%
Operating income CAGR (3Y) – 11.1% 0.3%
Net income growth (1Y) – 25.8% 78.2%
Net income CAGR (3Y) – 11.6% 35.8%
EPS growth (1Y) – 44.8% 79.0%
EPS CAGR (3Y) – 29.9% 42.4%
Operating cash flow growth (1Y) – 12.9% -4.2%
Operating cash flow CAGR (3Y) – 7.6% -2.0%
Free cash flow growth (1Y) – 8.4% -4.8%
Free cash flow CAGR (3Y) – 5.8% 0.7%

Profitability

14 metrics
MetricSLBTIOVABEAM
Gross margin – 48.4% –
EBITDA margin – -81.4% -228.0%
Operating margin – -92.7% -242.3%
Pretax margin – -90.4% -54.4%
Net margin – -89.1% -54.7%
FCF margin – -91.2% -238.9%
Operating cash flow margin – -81.3% -230.3%
Return on equity – -39.7% -7.6%
Return on assets – -31.4% -5.9%
Return on invested capital – – –
Return on capital employed – -37.0% -27.9%
Asset turnover – 0.4x 0.1x
Cash conversion (OCF / net income) – 0.9x 4.2x
Stock comp / revenue – 14.4% 52.2%

Financial Health

11 metrics
MetricSLBTIOVABEAM
Debt / assets – – 7.2%
Debt / equity – – 0.1x
Net debt / EBITDA – – 3.0x
Debt / FCF – – -0.3x
Liabilities / assets 21.8% 19.6% 23.0%
Equity / assets 78.2% 80.4% 77.0%
Interest coverage – – –
Current ratio 4.4x 4.3x 14.6x
Quick ratio 4.3x 3.7x 14.3x
Cash ratio 4.3x 2.8x 14.3x
Altman Z-score – 17.73 3.84

Shareholder Returns

7 metrics
MetricSLBTIOVABEAM
Dividend yield – – –
Net buyback yield – -4.4% -0.5%
Shareholder yield 0.0% -4.4% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSLBTIOVABEAM
EPS, next fiscal year – $-0.47FY2026 $-4.22FY2026
Revenue, next fiscal year – $434.71MFY2026 $49.46MFY2026
Revenue growth, next FY – +65.0%FY2026 -64.6%FY2026
Revenue growth, the year after – +33.0% +23.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSLBTIOVABEAM
Held by institutions – 63.3% 100.0%
Institutions holding – 292 277
Change in shares held, QoQ – +6.5% +1.0%
Institutions buying – 174 154
Institutions selling – 66 75
Buyers to sellers – 2.64 2.05

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SLBTIOVABEAM
SLBT 1.00 0.01 0.00
IOVA 0.01 1.00 0.32
BEAM 0.00 0.32 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SLBT, IOVA and BEAM?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: SL Science Holding (SLBT) $2.64B, Iovance Biotherapeutics (IOVA) $6.71B, Beam Therapeutics (BEAM) $2.97B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Iovance Biotherapeutics (IOVA) +34.5%, Beam Therapeutics (BEAM) +158.9%.

Which company is more profitable?

Beam Therapeutics (BEAM) has the highest net margin (Iovance Biotherapeutics (IOVA) -89.1%, Beam Therapeutics (BEAM) -54.7%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: SL Science Holding (SLBT) -88.3%, Iovance Biotherapeutics (IOVA) +576.3%, Beam Therapeutics (BEAM) +8.9%. Over five years, Iovance Biotherapeutics (IOVA) compounded fastest (Iovance Biotherapeutics (IOVA) -9.4%/yr, Beam Therapeutics (BEAM) -20.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Beam Therapeutics (BEAM) has been the steadiest (SL Science Holding (SLBT) 175.5%, Iovance Biotherapeutics (IOVA) 99.0%, Beam Therapeutics (BEAM) 70.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SLBT, IOVA and BEAM?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Beam Therapeutics (BEAM) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.