SHC vs NTRA vs BLLN Stock Comparison

Sotera Health, Natera and BillionToOne Prices as of Nov 5, 2026 Peers: Industry group
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SHC Sotera Health Co
$15.87 -13.0% 1M +0.4% 1Y
Market cap
$4.53B
P/E
26.1x
Revenue (TTM)
$1.23B
Div. yield
–
Diagnostic Labs Healthcare
6 wins
NTRA Natera, Inc.
$363.76 -9.2% 1M +82.0% 1Y
Market cap
$45.26B
P/E
–
Revenue (TTM)
$2.91B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
BLLN BillionToOne, Inc.
$112.39 +12.5% 1M
Market cap
$5.21B
P/E
113.3x
Revenue (TTM)
$436.87M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

11 decided of 12

Sotera Health leads on 6 of the 12 questions below (Sotera Health 6, Natera 3, BillionToOne 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSHCNTRABLLNLeader
Larger companyMarket capitalisation $4.53B $45.26B $5.21B NTRA
Cheaper on earningsLower P/E, profitable companies only 26.1x -274.7x 113.3x SHC
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.1x — 147.9x SHC
Faster revenue growthRevenue growth, trailing twelve months +6.9% +37.4% +71.9% BLLN
More profitableNet margin, trailing twelve months 14.1% -5.7% 10.5% SHC
Better return on capitalReturn on invested capital 9.2% -9.9% 6.9% SHC
Less leveragedLower net debt / EBITDA 3.1x 5.6x -9.1x BLLN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +0.4% +82.0% — NTRA
Better 5-year returnAnnualised price return, 5 years -10.1%/yr +25.7%/yr — NTRA
Less volatileAnnualised volatility, 1 year 30.4% 49.6% 93.3% SHC
Higher overall scoreMean of the five percentile scores vs peers 62/100 51/100 57/100 SHC

Percentile Scorecard

SHCNTRABLLN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSHCNTRABLLN
Valuation 57 #41 of 95 17 #79 of 95 21 #75 of 95
Growth 72 #25 of 88 77 #21 of 88 100 #1 of 88
Profitability 85 #14 of 87 31 #60 of 87 59 #36 of 87
Financial Health 34 #66 of 100 85 #16 of 100 98 #3 of 100
Shareholder Returns – 46 #33 of 60 7 #56 of 60
Overall 62 51 57
  • SHC ranked among 102 companies in Healthcare Providers
  • NTRA ranked among 102 companies in Healthcare Providers
  • BLLN ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSHCNTRABLLNSPY
1 month -13.0%-9.2%+12.5% -5.9%
3 months -16.1%+37.1%+22.6% -4.6%
6 months +1.3%+65.5%+21.0% +0.2%
Year to date -10.0%+58.8%+37.3% +7.5%
1 year +0.4%+82.0%— +8.2%
3 years +18.5%+744.0%— +68.3%
3 years, per year +5.8%+103.7%— +19.0%
5 years -41.1%+213.7%— +56.5%
5 years, per year -10.1%+25.7%— +9.4%
10 years —+4,204.9%— +251.5%
10 years, per year —+45.7%— +13.4%

Risk

MeasureSHCNTRABLLNSPY
Volatility, 1Y 30.4%49.6%93.3% 13.6%
Downside volatility, 1Y 31.1%48.1%106.1% 14.2%
Beta vs S&P 500, 1Y 1.001.331.49 1.00
Return / volatility, 1Y 0.011.65— 0.60
Max drawdown, 5Y -78.2%-75.9%-50.8% -25.4%
From 52-week high -18.9%-16.6%-25.1% -5.9%
52-week high $19.57$436.00$149.97 $779.14
52-week low $13.13$182.65$64.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSHCNTRABLLN
P/E now vs peer median 26.2xmedian 24.8x -318.1xmedian 24.8x 115.6xmedian 24.8x
P/S now vs peer median 3.7xmedian 1.6x 18.1xmedian 1.6x 12.3xmedian 1.6x
EV/EBITDA now vs peer median 11.4xmedian 15.9x -283.6xmedian 15.9x 94.0xmedian 15.9x
P/FCF now vs peer median 33.5xmedian 20.9x 1,001xmedian 20.9x 157.9xmedian 20.9x
P/B now vs peer median 6.2xmedian 3.3x 28.1xmedian 3.3x 9.4xmedian 3.3x
PEG now vs peer median 0.71median 0.88 -8.87median 0.88 —median 0.88

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSHCNTRABLLN
Revenue $1.23B $2.91B $436.87M
Gross profit $671.74M $1.84B $311.95M
Operating income $413.72M -$260.42M $44.69M
Net income $173.47M -$164.72M $49.39M
Free cash flow $135.43M $52.47M $33.91M
R&D – $856.40M $66.47M
EPS (diluted) $0.60 $-1.14 $0.86
Cash & equivalents $412.38M $1.10B $561.51M
Total debt $2.14B $80.30M $89.00M
Shares (diluted) 289.22M 144.07M 53.73M
Enterprise value $3.10B $40.89B $3.06B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSHCNTRABLLN
P/E 26.2x -318.1x 115.6x
P/FCF 33.5x 1,001x 157.9x
P/Operating cash flow 13.7x 246.8x 111.7x
P/S 3.7x 18.1x 12.3x
P/B 6.2x 28.1x 9.4x
P/Tangible book 9.7x 34.6x 9.4x
EV/EBITDA 11.4x -283.6x 94.0x
EV/EBIT 15.1x -197.7x 109.2x
EV/Revenue 5.1x 17.7x 11.2x
EV/FCF 46.2x 981.3x 143.9x
EV/Operating cash flow 18.9x 242.0x 101.9x
PEG (3Y EPS CAGR) 0.71 -8.87 –

Growth

14 metrics
MetricSHCNTRABLLN
Revenue growth (1Y) 6.9% 37.4% 71.9%
Revenue CAGR (3Y) 7.5% 43.3% –
Gross profit growth (1Y) 4.3% 41.1% 88.4%
Gross profit CAGR (3Y) 7.6% 68.2% –
Operating income growth (1Y) 11.4% 26.0% 844.7%
Operating income CAGR (3Y) 21.1% 19.7% –
Net income growth (1Y) 213.0% 46.7% 593.9%
Net income CAGR (3Y) 36.9% 30.9% –
EPS growth (1Y) 210.3% 49.3% 193.7%
EPS CAGR (3Y) 36.6% 35.9% –
Operating cash flow growth (1Y) 38.3% 9.5% 794.7%
Operating cash flow CAGR (3Y) 59.9% 40.7% –
Free cash flow growth (1Y) 56.4% -50.5% 934.5%
Free cash flow CAGR (3Y) 33.1% 29.4% –

Profitability

14 metrics
MetricSHCNTRABLLN
Gross margin 54.6% 63.3% 71.4%
EBITDA margin 44.7% -6.2% 11.9%
Operating margin 33.6% -9.0% 10.2%
Pretax margin 22.4% -7.7% 11.4%
Net margin 14.1% -5.7% 10.5%
FCF margin 11.0% 1.8% 7.8%
Operating cash flow margin 27.0% 7.3% 11.0%
Return on equity 24.8% -8.9% 9.0%
Return on assets 5.2% -6.1% 6.6%
Return on invested capital 9.2% -9.9% 6.9%
Return on capital employed 13.2% -12.5% 6.5%
Asset turnover 0.4x 1.1x 0.6x
Cash conversion (OCF / net income) 1.9x -1.3x 1.0x
Stock comp / revenue 3.0% 13.6% 7.0%

Financial Health

11 metrics
MetricSHCNTRABLLN
Debt / assets 63.1% 2.9% 11.7%
Debt / equity 2.9x 0.0x 0.2x
Net debt / EBITDA 3.1x 5.6x -9.1x
Debt / FCF 15.8x 1.5x 2.6x
Liabilities / assets 78.4% 32.0% 25.5%
Equity / assets 21.6% 68.0% 74.5%
Interest coverage – -70.8x 1,655x
Current ratio 3.1x 2.8x 11.2x
Quick ratio 2.7x 2.6x 10.7x
Cash ratio 1.8x 1.8x 9.3x
Altman Z-score 1.80 35.55 17.88

Shareholder Returns

7 metrics
MetricSHCNTRABLLN
Dividend yield – – –
Net buyback yield – -0.1% -5.7%
Shareholder yield – -0.1% -5.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSHCNTRABLLN
Forward P/E 17.1xFY2026 – 147.9xFY2026
EPS, next fiscal year $0.93FY2026 $-1.48FY2026 $0.76FY2026
EPS growth, next FY +8.1%FY2026 – +442.9%FY2026
EPS growth, the year after +22.6% – +22.4%
Revenue, next fiscal year $1.33BFY2026 $3.07BFY2026 $481.76MFY2026
Revenue growth, next FY +14.8%FY2026 +32.8%FY2026 +57.9%FY2026
Revenue growth, the year after -4.2% +7.2% +27.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSHCNTRABLLN
Held by institutions 100.0% 95.5% 32.6%
Institutions holding 316 850 155
Change in shares held, QoQ +5.9% +2.7% +34.7%
Institutions buying 220 515 127
Institutions selling 64 240 13
Buyers to sellers 3.44 2.15 9.77

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SHCNTRABLLN
SHC 1.00 0.35 0.13
NTRA 0.35 1.00 0.35
BLLN 0.13 0.35 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, SHC, NTRA and BLLN?

Natera (NTRA) is the largest by market capitalisation: Sotera Health (SHC) $4.53B, Natera (NTRA) $45.26B, BillionToOne (BLLN) $5.21B.

Which stock is cheaper, SHC, NTRA and BLLN?

Sotera Health (SHC) trades on the lowest price-to-earnings ratio (Sotera Health (SHC) 26.1x, Natera (NTRA) -274.7x, BillionToOne (BLLN) 113.3x). On next year's consensus earnings, Sotera Health (SHC) is cheapest (Sotera Health (SHC) 17.1x, BillionToOne (BLLN) 147.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: Sotera Health (SHC) +6.9%, Natera (NTRA) +37.4%, BillionToOne (BLLN) +71.9%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Sotera Health (SHC) 14.1%, Natera (NTRA) -5.7%, BillionToOne (BLLN) 10.5%). On return on invested capital, Sotera Health (SHC) leads (Sotera Health (SHC) 9.2%, Natera (NTRA) -9.9%, BillionToOne (BLLN) 6.9%).

Which stock has performed better?

Over the past year Natera (NTRA) returned the most: Sotera Health (SHC) +0.4%, Natera (NTRA) +82.0%. Over five years, Natera (NTRA) compounded fastest (Sotera Health (SHC) -10.1%/yr, Natera (NTRA) +25.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Sotera Health (SHC) 30.4%, Natera (NTRA) 49.6%, BillionToOne (BLLN) 93.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SHC, NTRA and BLLN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Sotera Health (SHC) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.