SHC vs GRAL vs NTRA Stock Comparison

Sotera Health, Grail and Natera Prices as of Oct 27, 2026 Peers: Industry group
SHC Sotera Health Co
$18.49 +0.8% 1M +10.7% 1Y
Market cap
$5.32B
P/E
32.6x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
5 wins
GRAL GRAIL, Inc.
$150.61 +18.7% 1M +77.2% 1Y
Market cap
$6.82B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare
NTRA Natera, Inc.
$410.82 -0.4% 1M +113.7% 1Y
Market cap
$61.29B
P/E
–
Revenue (TTM)
$2.71B
Div. yield
–
Diagnostic Labs Healthcare
4 wins

Head to Head

9 decided of 12

Sotera Health leads on 5 of the 12 questions below (Sotera Health 5, Natera 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionSHCGRALNTRALeader
Larger companyMarket capitalisation $5.32B $6.82B $61.29B NTRA
Cheaper on earningsLower P/E, profitable companies only 32.6x -17.4x -318.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 20.1x — — –
Faster revenue growthRevenue growth, trailing twelve months +8.1% +17.1% +37.8% NTRA
More profitableNet margin, trailing twelve months 13.4% -249.1% -7.1% SHC
Better return on capitalReturn on invested capital 9.1% — -11.7% SHC
Less leveragedLower net debt / EBITDA 3.3x — 4.5x SHC
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +10.7% +77.2% +113.7% NTRA
Better 5-year returnAnnualised price return, 5 years -5.8%/yr — +28.5%/yr NTRA
Less volatileAnnualised volatility, 1 year 28.4% 111.3% 47.8% SHC
Higher overall scoreMean of the five percentile scores vs peers 59/100 43/100 50/100 SHC

Percentile Scorecard

SHCGRALNTRA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisSHCGRALNTRA
Valuation 52 #45 of 92 8 #85 of 92 17 #77 of 92
Growth 66 #30 of 87 58 #37 of 87 71 #26 of 87
Profitability 82 #16 of 86 6 #81 of 86 33 #58 of 86
Financial Health 37 #62 of 97 99 #2 of 97 85 #15 of 97
Shareholder Returns – – 46 #31 of 56
Overall 59 43 50
  • SHC ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers
  • NTRA ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodSHCGRALNTRASPY
1 month +0.8%+18.7%-0.4% -0.2%
3 months +4.1%+133.8%+62.9% +3.9%
6 months +19.0%+188.5%+105.2% +8.2%
Year to date +4.8%+76.0%+79.3% +12.9%
1 year +10.7%+77.2%+113.7% +12.3%
3 years +47.8%—+973.8% +87.4%
3 years, per year +13.9%—+120.7% +23.3%
5 years -25.6%—+250.5% +67.9%
5 years, per year -5.8%—+28.5% +10.9%
10 years ——+4,464.7% +261.1%
10 years, per year ——+46.5% +13.7%

Risk

MeasureSHCGRALNTRASPY
Volatility, 1Y 28.4%111.3%47.8% 12.7%
Downside volatility, 1Y 27.0%126.1%44.5% 12.7%
Beta vs S&P 500, 1Y 1.012.691.23 1.00
Return / volatility, 1Y 0.380.692.38 0.97
Max drawdown, 5Y -78.2%-62.9%-76.4% -25.4%
From 52-week high -5.5%-2.3%-3.5% -1.2%
52-week high $19.57$154.08$425.64 $779.14
52-week low $13.13$43.03$182.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleSHCGRALNTRA
P/E now vs peer median 32.3xmedian 24.6x -16.6xmedian 24.6x -305.9xmedian 24.6x
P/S now vs peer median 4.3xmedian 1.6x 42.8xmedian 1.6x 21.8xmedian 1.6x
EV/EBITDA now vs peer median 13.0xmedian 14.6x -14.5xmedian 14.6x -258.6xmedian 14.6x
P/FCF now vs peer median 46.8xmedian 21.6x -22.7xmedian 21.6x 700.7xmedian 21.6x
P/B now vs peer median 7.9xmedian 3.2x 2.6xmedian 3.2x 32.4xmedian 3.2x
PEG now vs peer median 0.86median 0.66 —median 0.66 -9.22median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsSHCGRALNTRA
Revenue $1.22B $157.21M $2.71B
Gross profit $668.51M $75.51M $1.71B
Operating income $411.34M -$559.25M -$289.67M
Net income $163.48M -$391.59M -$192.36M
Free cash flow $112.70M -$296.16M $84.20M
R&D – $190.72M $787.38M
EPS (diluted) $0.57 $-9.08 $-1.34
Cash & equivalents $356.72M $55.65M $1.10B
Total debt $2.14B – $80.29M
Shares (diluted) 288.15M 43.11M 143.28M
Enterprise value $4.01B $3.69B $56.97B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricSHCGRALNTRA
P/E 32.3x -16.6x -305.9x
P/FCF 46.8x -22.7x 700.7x
P/Operating cash flow 18.1x -22.8x 258.5x
P/S 4.3x 42.8x 21.8x
P/B 7.9x 2.6x 32.4x
P/Tangible book 13.3x 8.8x 40.4x
EV/EBITDA 13.0x -14.5x -258.6x
EV/EBIT 17.2x -10.5x -200.2x
EV/Revenue 5.8x 37.3x 21.4x
EV/FCF 62.6x -19.8x 688.6x
EV/Operating cash flow 24.2x -19.9x 254.0x
PEG (3Y EPS CAGR) 0.86 – -9.22

Growth

14 metrics
MetricSHCGRALNTRA
Revenue growth (1Y) 8.1% 17.1% 37.8%
Revenue CAGR (3Y) 7.6% – 42.7%
Gross profit growth (1Y) 7.1% 30.2% 43.6%
Gross profit CAGR (3Y) 8.1% – 68.1%
Operating income growth (1Y) 21.8% 11.6% 1.3%
Operating income CAGR (3Y) 23.2% – 17.3%
Net income growth (1Y) 580.5% 11.6% 24.0%
Net income CAGR (3Y) 37.7% – 27.8%
EPS growth (1Y) 574.9% 26.6% 27.7%
EPS CAGR (3Y) 37.5% – 33.2%
Operating cash flow growth (1Y) 9.8% 20.3% 22.2%
Operating cash flow CAGR (3Y) 61.3% – 38.6%
Free cash flow growth (1Y) 0.0% 20.3% -26.8%
Free cash flow CAGR (3Y) 32.6% – 30.4%

Profitability

14 metrics
MetricSHCGRALNTRA
Gross margin 55.0% 48.0% 63.2%
EBITDA margin 44.6% -257.6% -8.3%
Operating margin 33.8% -355.7% -10.7%
Pretax margin 21.7% -336.8% -9.3%
Net margin 13.4% -249.1% -7.1%
FCF margin 9.3% -188.4% 3.1%
Operating cash flow margin 24.0% -187.5% 8.4%
Return on equity 25.4% -15.5% -10.7%
Return on assets 5.0% -13.9% -7.3%
Return on invested capital 9.1% – -11.7%
Return on capital employed 13.5% -20.4% -13.9%
Asset turnover 0.4x 0.1x 1.0x
Cash conversion (OCF / net income) 1.8x 0.8x -1.2x
Stock comp / revenue 3.1% 40.9% 14.1%

Financial Health

11 metrics
MetricSHCGRALNTRA
Debt / assets 64.7% – 3.0%
Debt / equity 3.2x – 0.0x
Net debt / EBITDA 3.3x – 4.5x
Debt / FCF 19.0x – 1.0x
Liabilities / assets 79.9% 10.6% 31.5%
Equity / assets 20.1% 89.4% 68.5%
Interest coverage – – -75.9x
Current ratio 2.8x 10.9x 3.0x
Quick ratio 2.4x 10.6x 2.8x
Cash ratio 1.5x 10.3x 2.0x
Altman Z-score 1.94 8.04 41.96

Shareholder Returns

7 metrics
MetricSHCGRALNTRA
Dividend yield – – –
Net buyback yield – – -0.1%
Shareholder yield – – -0.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusSHCGRALNTRA
Forward P/E 20.1xFY2026 – –
EPS, next fiscal year $0.92FY2026 $-9.05FY2026 $-1.48FY2026
EPS growth, next FY +7.0%FY2026 – –
EPS growth, the year after +21.7% – –
Revenue, next fiscal year $1.33BFY2026 $169.78MFY2026 $3.07BFY2026
Revenue growth, next FY +14.8%FY2026 +15.4%FY2026 +32.8%FY2026
Revenue growth, the year after -4.2% +38.2% +7.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersSHCGRALNTRA
Held by institutions 100.0% 85.4% 95.5%
Institutions holding 316 372 847
Change in shares held, QoQ +5.9% +8.4% +2.7%
Institutions buying 220 182 513
Institutions selling 64 100 240
Buyers to sellers 3.44 1.82 2.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

SHCGRALNTRA
SHC 1.00 0.22 0.36
GRAL 0.22 1.00 0.43
NTRA 0.36 0.43 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, SHC, GRAL and NTRA?

Natera (NTRA) is the largest by market capitalisation: Sotera Health (SHC) $5.32B, Grail (GRAL) $6.82B, Natera (NTRA) $61.29B.

Which company is growing faster?

Natera (NTRA) grew revenue fastest over the trailing twelve months: Sotera Health (SHC) +8.1%, Grail (GRAL) +17.1%, Natera (NTRA) +37.8%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Sotera Health (SHC) 13.4%, Grail (GRAL) -249.1%, Natera (NTRA) -7.1%). On return on invested capital, Sotera Health (SHC) leads (Sotera Health (SHC) 9.1%, Natera (NTRA) -11.7%).

Which stock has performed better?

Over the past year Natera (NTRA) returned the most: Sotera Health (SHC) +10.7%, Grail (GRAL) +77.2%, Natera (NTRA) +113.7%. Over five years, Natera (NTRA) compounded fastest (Sotera Health (SHC) -5.8%/yr, Natera (NTRA) +28.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Sotera Health (SHC) 28.4%, Grail (GRAL) 111.3%, Natera (NTRA) 47.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, SHC, GRAL and NTRA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Sotera Health (SHC) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.