QGEN vs ILMN vs RGEN Stock Comparison

Qiagen, Illumina and Repligen Prices as of Oct 28, 2026 Peers: Industry group
QGEN Qiagen N.V.
$50.33 +11.8% 1M -0.3% 1Y
Market cap
$10.95B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
6 wins
ILMN Illumina, Inc.
$288.79 +6.2% 1M +195.3% 1Y
Market cap
$43.51B
P/E
52.7x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
4 wins
RGEN Repligen Corp
$184.69 -4.8% 1M +21.9% 1Y
Market cap
$10.63B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
1 win

Head to Head

11 decided of 12

Qiagen leads on 6 of the 12 questions below (Qiagen 6, Illumina 4, Repligen 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionQGENILMNRGENLeader
Larger companyMarket capitalisation $10.95B $43.51B $10.63B ILMN
Cheaper on earningsLower P/E, profitable companies only 26.7x 52.7x -900.3x QGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 21.4x 57.9x 95.2x QGEN
Faster revenue growthRevenue growth, trailing twelve months +3.0% +4.9% +13.8% RGEN
More profitableNet margin, trailing twelve months 19.5% 18.4% — QGEN
Better return on capitalReturn on invested capital 7.9% 15.1% — ILMN
Less leveragedLower net debt / EBITDA 1.3x 0.7x — ILMN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -0.3% +195.3% +21.9% ILMN
Better 5-year returnAnnualised price return, 5 years -4.2%/yr -6.5%/yr -8.7%/yr QGEN
Less volatileAnnualised volatility, 1 year 35.7% 50.4% 46.1% QGEN
Higher overall scoreMean of the five percentile scores vs peers 71/100 65/100 56/100 QGEN

Percentile Scorecard

QGENILMNRGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisQGENILMNRGEN
Valuation 76 #55 of 227 50 #115 of 227 42 #133 of 227
Growth 30 #153 of 219 46 #119 of 219 31 #152 of 219
Profitability 93 #16 of 205 97 #8 of 205 69 #64 of 205
Financial Health 63 #88 of 237 51 #116 of 237 84 #40 of 237
Shareholder Returns 94 #9 of 135 83 #24 of 135 –
Overall 71 65 56
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • RGEN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodQGENILMNRGENSPY
1 month +11.8%+6.2%-4.8% +0.9%
3 months +20.3%+48.2%+30.8% +5.9%
6 months +49.7%+139.9%+63.3% +8.5%
Year to date +6.3%+120.2%+12.7% +13.3%
1 year -0.3%+195.3%+21.9% +12.4%
3 years +24.9%+171.8%+54.4% +88.1%
3 years, per year +7.7%+39.6%+15.6% +23.5%
5 years -19.1%-28.5%-36.4% +68.2%
5 years, per year -4.2%-6.5%-8.7% +11.0%
10 years +75.6%+114.2%+546.2% +263.4%
10 years, per year +5.8%+7.9%+20.5% +13.8%

Risk

MeasureQGENILMNRGENSPY
Volatility, 1Y 35.7%50.4%46.1% 12.7%
Downside volatility, 1Y 30.5%39.0%46.1% 12.7%
Beta vs S&P 500, 1Y 0.470.831.22 1.00
Return / volatility, 1Y -0.013.880.47 0.98
Max drawdown, 5Y -48.2%-82.9%-66.2% -25.4%
From 52-week high -9.6%-1.7%-5.1% -0.9%
52-week high $55.66$293.69$194.57 $779.14
52-week low $32.63$95.03$102.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleQGENILMNRGEN
P/E now vs peer median 26.7xmedian 28.8x 52.9xmedian 28.8x -882.7xmedian 28.8x
P/S now vs peer median 5.2xmedian 3.0x 9.7xmedian 3.0x 12.9xmedian 3.0x
EV/EBITDA now vs peer median 18.1xmedian 17.4x 38.5xmedian 17.4x —median 17.4x
P/FCF now vs peer median 11.0xmedian 25.7x 46.8xmedian 25.7x 98.1xmedian 25.7x
P/B now vs peer median 3.3xmedian 2.4x 15.4xmedian 2.4x 5.0xmedian 2.4x
PEG now vs peer median 3.61median 1.03 1.75median 1.03 31.05median 1.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsQGENILMNRGEN
Revenue $2.10B $4.49B $805.61M
Gross profit $1.31B $2.98B –
Operating income $445.43M $882.00M $18.24M
Net income $409.32M $825.00M $26.59M
Free cash flow $991.33M $931.00M –
R&D $194.67M $960.00M $56.43M
EPS (diluted) $1.87 $5.39 $-0.21
Cash & equivalents $768.50M $1.04B $726.96M
Total debt $6.86B $1.99B –
Shares (diluted) 218.88M 153.00M 56.64M
Enterprise value $6.72B $38.28B $10.63B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricQGENILMNRGEN
P/E 26.7x 52.9x -882.7x
P/FCF 11.0x 46.8x 98.1x
P/Operating cash flow 16.7x 39.8x 80.2x
P/S 5.2x 9.7x 12.9x
P/B 3.3x 15.4x 5.0x
P/Tangible book 3.6x 18.0x 5.8x
EV/EBITDA 18.1x 38.5x –
EV/EBIT 26.4x 50.4x –
EV/Revenue 5.6x 9.9x 12.9x
EV/FCF 11.9x 47.7x –
EV/Operating cash flow 18.0x 40.6x 80.2x
PEG (3Y EPS CAGR) 3.61 1.75 31.05

Growth

14 metrics
MetricQGENILMNRGEN
Revenue growth (1Y) 3.0% 4.9% 13.8%
Revenue CAGR (3Y) 2.0% -1.0% 7.3%
Gross profit growth (1Y) 1.7% 4.6% –
Gross profit CAGR (3Y) 1.3% 2.9% –
Operating income growth (1Y) -4.9% -31.8% 2,185%
Operating income CAGR (3Y) 3.3% 28.3% -40.5%
Net income growth (1Y) 143.9% -34.4% 1,430%
Net income CAGR (3Y) 6.7% 30.0% -35.9%
EPS growth (1Y) 12.5% -32.7% -777.9%
EPS CAGR (3Y) 7.4% 30.1% -28.4%
Operating cash flow growth (1Y) -3.0% -5.1% -0.8%
Operating cash flow CAGR (3Y) 8.0% 38.1% -4.0%
Free cash flow growth (1Y) 2.3% -9.7% –
Free cash flow CAGR (3Y) 10.5% 105.0% –

Profitability

14 metrics
MetricQGENILMNRGEN
Gross margin 62.2% 66.4% –
EBITDA margin 31.0% 25.7% –
Operating margin 21.2% 19.6% –
Pretax margin 22.0% 22.6% –
Net margin 19.5% 18.4% –
FCF margin 47.2% 20.7% –
Operating cash flow margin 31.2% 24.4% 16.1%
Return on equity 12.2% 29.9% 1.3%
Return on assets 7.0% 12.5% 0.9%
Return on invested capital 7.9% 15.1% –
Return on capital employed 8.5% 17.5% –
Asset turnover 0.4x 0.7x 0.3x
Cash conversion (OCF / net income) 1.6x 1.3x 4.9x
Stock comp / revenue 2.1% 5.9% 4.2%

Financial Health

11 metrics
MetricQGENILMNRGEN
Debt / assets 27.9% 29.9% –
Debt / equity 0.5x 0.7x –
Net debt / EBITDA 1.3x 0.7x –
Debt / FCF 1.7x 2.1x –
Liabilities / assets 43.0% 57.3% 28.5%
Equity / assets 57.0% 42.7% 71.5%
Interest coverage 11.3x 8.9x –
Current ratio 2.8x 1.8x 9.9x
Quick ratio 2.0x 1.2x –
Cash ratio 1.4x 0.7x –
Altman Z-score 4.08 8.19 –

Shareholder Returns

7 metrics
MetricQGENILMNRGEN
Dividend yield 5.2% – –
Net buyback yield 0.6% 1.2% –
Shareholder yield 5.8% 1.2% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusQGENILMNRGEN
Forward P/E 21.4xFY2026 57.9xFY2026 95.2xFY2026
EPS, next fiscal year $2.35FY2026 $4.99FY2026 $1.94FY2026
EPS growth, next FY -1.3%FY2026 +3.1%FY2026 +13.5%FY2026
EPS growth, the year after +17.4% +25.7% +29.4%
Revenue, next fiscal year $2.25BFY2026 $4.52BFY2026 $773.94MFY2026
Revenue growth, next FY +7.8%FY2026 +4.1%FY2026 +4.8%FY2026
Revenue growth, the year after -2.8% +12.0% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersQGENILMNRGEN
Held by institutions 0.0% 100.0% 100.0%
Institutions holding 1 933 482
Change in shares held, QoQ – +0.0% +1.2%
Institutions buying 0 463 272
Institutions selling 0 330 141
Buyers to sellers – 1.40 1.93

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

QGENILMNRGEN
QGEN 1.00 0.39 0.38
ILMN 0.39 1.00 0.42
RGEN 0.38 0.42 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, QGEN, ILMN and RGEN?

Illumina (ILMN) is the largest by market capitalisation: Qiagen (QGEN) $10.95B, Illumina (ILMN) $43.51B, Repligen (RGEN) $10.63B.

Which stock is cheaper, QGEN, ILMN and RGEN?

Qiagen (QGEN) trades on the lowest price-to-earnings ratio (Qiagen (QGEN) 26.7x, Illumina (ILMN) 52.7x, Repligen (RGEN) -900.3x). On next year's consensus earnings, Qiagen (QGEN) is cheapest (Qiagen (QGEN) 21.4x, Illumina (ILMN) 57.9x, Repligen (RGEN) 95.2x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Qiagen (QGEN) +3.0%, Illumina (ILMN) +4.9%, Repligen (RGEN) +13.8%.

Which company is more profitable?

Qiagen (QGEN) has the highest net margin (Qiagen (QGEN) 19.5%, Illumina (ILMN) 18.4%). On return on invested capital, Illumina (ILMN) leads (Qiagen (QGEN) 7.9%, Illumina (ILMN) 15.1%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Qiagen (QGEN) -0.3%, Illumina (ILMN) +195.3%, Repligen (RGEN) +21.9%. Over five years, Qiagen (QGEN) compounded fastest (Qiagen (QGEN) -4.2%/yr, Illumina (ILMN) -6.5%/yr, Repligen (RGEN) -8.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Qiagen (QGEN) has been the steadiest (Qiagen (QGEN) 35.7%, Illumina (ILMN) 50.4%, Repligen (RGEN) 46.1%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, QGEN, ILMN and RGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Qiagen (QGEN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.