QGEN vs CDXS vs GRFS Stock Comparison

Qiagen, Codexis and Grifols Prices as of Oct 27, 2026 Peers: Industry group
QGEN Qiagen N.V.
$50.18 +13.6% 1M -1.5% 1Y
Market cap
$10.91B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
6 wins
CDXS Codexis, Inc.
$1.28 -3.0% 1M -50.8% 1Y
Market cap
$117.46M
P/E
–
Revenue (TTM)
$77.68M
Div. yield
–
Life Sciences Tools Healthcare
2 wins
GRFS Grifols SA
$8.10 +10.2% 1M -13.6% 1Y
Market cap
$5.62B
P/E
12.1x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
3 wins

Head to Head

11 decided of 12

Qiagen leads on 6 of the 12 questions below (Qiagen 6, Grifols 3, Codexis 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionQGENCDXSGRFSLeader
Larger companyMarket capitalisation $10.91B $117.46M $5.62B QGEN
Cheaper on earningsLower P/E, profitable companies only 26.7x -3.8x 12.1x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 21.4x — 8.6x GRFS
Faster revenue growthRevenue growth, trailing twelve months +3.0% +35.9% — CDXS
More profitableNet margin, trailing twelve months 19.5% -39.6% — QGEN
Better return on capitalReturn on invested capital 7.9% -35.1% — QGEN
Less leveragedLower net debt / EBITDA 1.3x 0.7x — CDXS
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -1.5% -50.8% -13.6% QGEN
Better 5-year returnAnnualised price return, 5 years -3.8%/yr -48.4%/yr -9.4%/yr QGEN
Less volatileAnnualised volatility, 1 year 35.8% 86.7% 32.4% GRFS
Higher overall scoreMean of the five percentile scores vs peers 71/100 45/100 56/100 QGEN

Percentile Scorecard

QGENCDXSGRFS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisQGENCDXSGRFS
Valuation 76 #56 of 227 40 #137 of 227 99 #7 of 625
Growth 31 #151 of 219 67 #73 of 219 –
Profitability 93 #16 of 206 43 #117 of 206 –
Financial Health 63 #89 of 238 30 #166 of 238 14 #564 of 656
Shareholder Returns 94 #9 of 134 42 #78 of 134 56 #161 of 365
Overall 71 45 56
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics
  • CDXS ranked among 247 companies in Medical Devices and Diagnostics
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodQGENCDXSGRFSSPY
1 month +13.6%-3.0%+10.2% -0.2%
3 months +18.8%-14.7%+1.2% +3.9%
6 months +47.5%-54.6%+0.4% +8.2%
Year to date +6.0%-21.5%-13.4% +12.9%
1 year -1.5%-50.8%-13.6% +12.3%
3 years +24.5%-17.4%+3.3% +87.4%
3 years, per year +7.6%-6.2%+1.1% +23.3%
5 years -17.4%-96.3%-39.0% +67.9%
5 years, per year -3.8%-48.4%-9.4% +10.9%
10 years +74.3%-71.6%-44.7% +261.1%
10 years, per year +5.7%-11.8%-5.8% +13.7%

Risk

MeasureQGENCDXSGRFSSPY
Volatility, 1Y 35.8%86.7%32.4% 12.7%
Downside volatility, 1Y 30.4%91.1%34.1% 12.7%
Beta vs S&P 500, 1Y 0.471.850.95 1.00
Return / volatility, 1Y -0.04-0.59-0.42 0.97
Max drawdown, 5Y -48.2%-97.7%-58.8% -25.4%
From 52-week high -9.8%-55.1%-16.7% -1.2%
52-week high $55.66$2.85$9.72 $779.14
52-week low $32.63$0.98$7.02 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleQGENCDXSGRFS
P/E now vs peer median 26.6xmedian 29.6x -3.8xmedian 29.6x 12.1xmedian 17.2x
P/S now vs peer median 5.2xmedian 2.9x 1.5xmedian 2.9x 0.6xmedian 9.0x
EV/EBITDA now vs peer median 18.0xmedian 17.4x -4.9xmedian 17.4x —median 16.3x
P/FCF now vs peer median 11.0xmedian 22.3x -9.6xmedian 22.3x 7.8xmedian 18.7x
P/B now vs peer median 3.2xmedian 2.3x 3.5xmedian 2.3x 0.6xmedian 2.2x
PEG now vs peer median 3.60median 1.04 -0.14median 1.04 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsQGENCDXSGRFS
Revenue $2.10B $77.68M –
Gross profit $1.31B $67.60M –
Operating income $445.43M -$27.66M –
Net income $409.32M -$30.72M –
Free cash flow $991.33M -$12.18M –
R&D $194.67M $48.74M –
EPS (diluted) $1.87 $-0.34 –
Cash & equivalents $768.50M $27.17M $969.15M
Total debt $6.86B $40.88M $44.00B
Shares (diluted) 218.88M 91.05M 681.57M
Enterprise value $6.69B -$139.59M $1.96B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricQGENCDXSGRFS
P/E 26.6x -3.8x 12.1x
P/FCF 11.0x -9.6x 7.8x
P/Operating cash flow 16.6x -11.2x –
P/S 5.2x 1.5x 0.6x
P/B 3.2x 3.5x 0.6x
P/Tangible book 3.6x 3.5x 1.0x
EV/EBITDA 18.0x -4.9x –
EV/EBIT 26.3x -3.7x –
EV/Revenue 5.6x 1.3x –
EV/FCF 11.8x -8.5x –
EV/Operating cash flow 17.9x -9.9x –
PEG (3Y EPS CAGR) 3.60 -0.14 –

Growth

14 metrics
MetricQGENCDXSGRFS
Revenue growth (1Y) 3.0% 35.9% –
Revenue CAGR (3Y) 2.0% -7.8% –
Gross profit growth (1Y) 1.7% 52.4% –
Gross profit CAGR (3Y) 1.3% -2.6% –
Operating income growth (1Y) -4.9% 51.7% –
Operating income CAGR (3Y) 3.3% 22.8% –
Net income growth (1Y) 143.9% 52.7% –
Net income CAGR (3Y) 6.7% 18.5% –
EPS growth (1Y) 12.5% 55.7% –
EPS CAGR (3Y) 7.4% 26.2% –
Operating cash flow growth (1Y) -3.0% 83.0% –
Operating cash flow CAGR (3Y) 8.0% -152.3% –
Free cash flow growth (1Y) 2.3% 82.0% –
Free cash flow CAGR (3Y) 10.5% -26.3% –

Profitability

14 metrics
MetricQGENCDXSGRFS
Gross margin 62.2% 87.0% –
EBITDA margin 31.0% -27.0% –
Operating margin 21.2% -35.6% –
Pretax margin 22.0% -39.5% –
Net margin 19.5% -39.6% –
FCF margin 47.2% -15.7% –
Operating cash flow margin 31.2% -13.4% –
Return on equity 12.2% -80.6% –
Return on assets 7.0% -24.6% –
Return on invested capital 7.9% -35.1% –
Return on capital employed 8.5% -27.3% –
Asset turnover 0.4x 0.6x –
Cash conversion (OCF / net income) 1.6x 0.3x –
Stock comp / revenue 2.1% 9.9% –

Financial Health

11 metrics
MetricQGENCDXSGRFS
Debt / assets 27.9% 34.0% 48.9%
Debt / equity 0.5x 1.2x 1.3x
Net debt / EBITDA 1.3x 0.7x –
Debt / FCF 1.7x -3.4x –
Liabilities / assets 43.0% 72.5% 61.4%
Equity / assets 57.0% 27.5% 38.6%
Interest coverage 11.3x – –
Current ratio 2.8x 3.1x 2.5x
Quick ratio 2.0x 2.9x 0.8x
Cash ratio 1.4x 2.3x 0.4x
Altman Z-score 4.07 -6.14 –

Shareholder Returns

7 metrics
MetricQGENCDXSGRFS
Dividend yield 5.3% – 1.4%
Net buyback yield 0.6% -0.3% –
Shareholder yield 5.8% -0.3% 1.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusQGENCDXSGRFS
Forward P/E 21.4xFY2026 – 8.6xFY2026
EPS, next fiscal year $2.35FY2026 $-0.37FY2026 $0.94FY2026
EPS growth, next FY -1.3%FY2026 – +10.6%FY2026
EPS growth, the year after +17.4% – +26.6%
Revenue, next fiscal year $2.25BFY2026 $77.93MFY2026 $8.88BFY2026
Revenue growth, next FY +7.8%FY2026 +10.7%FY2026 +0.0%FY2026
Revenue growth, the year after -2.8% +9.2% +10.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersQGENCDXSGRFS
Held by institutions 0.0% 71.0% 21.0%
Institutions holding 1 148 166
Change in shares held, QoQ – -2.4% -0.5%
Institutions buying 0 88 73
Institutions selling 0 36 65
Buyers to sellers – 2.44 1.12

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

QGENCDXSGRFS
QGEN 1.00 0.00 0.18
CDXS 0.00 1.00 0.17
GRFS 0.18 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, QGEN, CDXS and GRFS?

Qiagen (QGEN) is the largest by market capitalisation: Qiagen (QGEN) $10.91B, Codexis (CDXS) $117.46M, Grifols (GRFS) $5.62B.

Which stock is cheaper, QGEN, CDXS and GRFS?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Qiagen (QGEN) 26.7x, Codexis (CDXS) -3.8x, Grifols (GRFS) 12.1x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Qiagen (QGEN) 21.4x, Grifols (GRFS) 8.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Codexis (CDXS) grew revenue fastest over the trailing twelve months: Qiagen (QGEN) +3.0%, Codexis (CDXS) +35.9%.

Which company is more profitable?

Qiagen (QGEN) has the highest net margin (Qiagen (QGEN) 19.5%, Codexis (CDXS) -39.6%). On return on invested capital, Qiagen (QGEN) leads (Qiagen (QGEN) 7.9%, Codexis (CDXS) -35.1%).

Which stock has performed better?

Over the past year Qiagen (QGEN) returned the most: Qiagen (QGEN) -1.5%, Codexis (CDXS) -50.8%, Grifols (GRFS) -13.6%. Over five years, Qiagen (QGEN) compounded fastest (Qiagen (QGEN) -3.8%/yr, Codexis (CDXS) -48.4%/yr, Grifols (GRFS) -9.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Grifols (GRFS) has been the steadiest (Qiagen (QGEN) 35.8%, Codexis (CDXS) 86.7%, Grifols (GRFS) 32.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, QGEN, CDXS and GRFS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Qiagen (QGEN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.