PFE vs TMO vs GSK Stock Comparison

Pfizer, Thermo Fisher Scientific and Gsk Prices as of Oct 26, 2026 Peers: Industry group
PFE Pfizer Inc
$29.79 +3.9% 1M +20.3% 1Y
Market cap
$169.97B
P/E
39.2x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
2 wins
GSK GSK plc
$51.10 +3.8% 1M +18.2% 1Y
Market cap
$103.23B
P/E
7.8x
Revenue (TTM)
$76.55B
Div. yield
–
Pharmaceuticals Healthcare
6 wins

Head to Head

9 decided of 12

Gsk leads on 6 of the 12 questions below (Gsk 6, Pfizer 2, Thermo Fisher Scientific 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPFETMOGSKLeader
Larger companyMarket capitalisation $169.97B $257.69B $103.23B TMO
Cheaper on earningsLower P/E, profitable companies only 39.2x 36.4x 7.8x GSK
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.5x 26.4x 10.1x GSK
Faster revenue growthRevenue growth, trailing twelve months -0.2% +8.3% +87.0% GSK
More profitableNet margin, trailing twelve months 6.8% — 17.3% GSK
Better return on capitalReturn on invested capital 13.4% — — –
Less leveragedLower net debt / EBITDA 1.9x — — –
Higher dividend yieldTrailing dividend yield 0.06% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +20.3% +19.6% +18.2% PFE
Better 5-year returnAnnualised price return, 5 years -7.1%/yr +2.3%/yr +4.8%/yr GSK
Less volatileAnnualised volatility, 1 year 21.7% 29.9% 26.2% PFE
Higher overall scoreMean of the five percentile scores vs peers 65/100 51/100 79/100 GSK

Percentile Scorecard

PFETMOGSK

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPFETMOGSK
Valuation 94 #37 of 626 49 #116 of 228 83 #109 of 626
Growth 23 #466 of 604 40 #133 of 221 77 #141 of 604
Profitability 92 #46 of 555 70 #63 of 208 96 #24 of 555
Financial Health 24 #502 of 658 – 54 #303 of 658
Shareholder Returns 91 #35 of 368 44 #77 of 137 85 #57 of 368
Overall 65 51 79
  • PFE ranked among 673 companies in Pharmaceuticals and Biotechnology
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • GSK ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPFETMOGSKSPY
1 month +3.9%+1.7%+3.8% -0.8%
3 months +20.8%+22.4%-1.7% +3.5%
6 months +11.2%+46.3%-5.8% +7.0%
Year to date +19.6%+18.2%+4.2% +12.2%
1 year +20.3%+19.6%+18.2% +13.0%
3 years -1.1%+58.7%+47.9% +86.3%
3 years, per year -0.4%+16.7%+13.9% +23.1%
5 years -30.7%+11.8%+26.4% +68.6%
5 years, per year -7.1%+2.3%+4.8% +11.0%
10 years -8.1%+362.6%+26.7% +258.0%
10 years, per year -0.8%+16.6%+2.4% +13.6%

Risk

MeasurePFETMOGSKSPY
Volatility, 1Y 21.7%29.9%26.2% 12.7%
Downside volatility, 1Y 21.1%28.3%23.5% 12.7%
Beta vs S&P 500, 1Y 0.230.620.22 1.00
Return / volatility, 1Y 0.940.660.69 1.02
Max drawdown, 5Y -64.8%-41.5%-38.8% -25.4%
From 52-week high -2.0%-1.7%-16.5% -1.8%
52-week high $30.41$696.55$61.18 $779.14
52-week low $23.67$438.34$43.70 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePFETMOGSK
P/E now vs peer median 39.2xmedian 17.1x 35.9xmedian 30.6x 7.8xmedian 17.1x
P/S now vs peer median 2.7xmedian 8.8x 5.3xmedian 3.0x 1.4xmedian 8.8x
EV/EBITDA now vs peer median 8.2xmedian 17.1x —median 17.5x —median 17.1x
P/FCF now vs peer median 15.5xmedian 18.0x 34.0xmedian 23.3x —median 18.0x
P/B now vs peer median 2.0xmedian 2.1x 4.6xmedian 2.4x 4.8xmedian 2.1x
PEG now vs peer median -0.95median 0.31 4.74median 0.87 -0.74median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPFETMOGSK
Revenue $63.70B $47.35B $76.55B
Gross profit $46.61B – $55.94B
Operating income $20.39B $8.47B $17.79B
Net income $4.36B $7.09B $3.57B
Free cash flow $10.99B – –
R&D $11.05B $1.40B $19.22B
EPS (diluted) $0.76 $19.06 $6.43
Cash & equivalents $976.00M $5.46B $4.12B
Total debt $63.19B – -$24.25B
Shares (diluted) 5.70B 371.00M 2.06B
Enterprise value $116.62B $257.69B $85.55B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPFETMOGSK
P/E 39.2x 35.9x 7.8x
P/FCF 15.5x 34.0x –
P/Operating cash flow 12.7x 27.2x –
P/S 2.7x 5.3x 1.4x
P/B 2.0x 4.6x 4.8x
P/Tangible book 4.4x 6.9x 221.8x
EV/EBITDA 8.2x – –
EV/EBIT 10.9x – 4.6x
EV/Revenue 3.5x 5.3x 1.1x
EV/FCF 20.1x – –
EV/Operating cash flow 16.5x 27.2x –
PEG (3Y EPS CAGR) -0.95 4.74 -0.74

Growth

14 metrics
MetricPFETMOGSK
Revenue growth (1Y) -0.2% 8.3% 87.0%
Revenue CAGR (3Y) -7.0% 2.9% 29.4%
Gross profit growth (1Y) 1.2% – 91.4%
Gross profit CAGR (3Y) -5.6% – 30.7%
Operating income growth (1Y) 1.5% 12.8% 168.3%
Operating income CAGR (3Y) -9.9% 7.2% 26.4%
Net income growth (1Y) -59.6% 7.9% -38.4%
Net income CAGR (3Y) -41.3% 6.2% -51.1%
EPS growth (1Y) -59.7% 9.7% 201.0%
EPS CAGR (3Y) -41.3% 7.6% -10.5%
Operating cash flow growth (1Y) -11.8% 21.9% –
Operating cash flow CAGR (3Y) -2.7% 4.5% –
Free cash flow growth (1Y) -11.7% – –
Free cash flow CAGR (3Y) 1.0% – –

Profitability

14 metrics
MetricPFETMOGSK
Gross margin 73.2% – 73.1%
EBITDA margin 42.4% – –
Operating margin 32.0% – 23.2%
Pretax margin 6.6% – 21.6%
Net margin 6.8% – 17.3%
FCF margin 17.2% – –
Operating cash flow margin 21.0% 19.7% –
Return on equity 5.0% 13.2% 77.6%
Return on assets 2.1% 6.2% 21.6%
Return on invested capital 13.4% – –
Return on capital employed 11.9% – 16.0%
Asset turnover 0.3x 0.4x 0.9x
Cash conversion (OCF / net income) 3.1x 1.3x –
Stock comp / revenue 1.5% – –

Financial Health

11 metrics
MetricPFETMOGSK
Debt / assets 31.4% – -29.6%
Debt / equity 0.7x – -1.1x
Net debt / EBITDA 1.9x – –
Debt / FCF 5.8x – –
Liabilities / assets 57.5% – 72.2%
Equity / assets 42.5% 47.9% 27.8%
Interest coverage – – 10.9x
Current ratio 1.3x 1.8x -0.8x
Quick ratio 0.7x – -0.5x
Cash ratio 0.4x – -0.1x
Altman Z-score 2.36 – 3.79

Shareholder Returns

7 metrics
MetricPFETMOGSK
Dividend yield 5.8% 0.3% 3.5%
Net buyback yield – – –
Shareholder yield 5.8% 0.3% 3.5%
Payout ratio (earnings) 224.5% – –
Payout ratio (FCF) 89.1% – –
Dividend growth (1Y) 1.5% – –
Dividend CAGR (3Y) 2.4% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPFETMOGSK
Forward P/E 10.5xFY2026 26.4xFY2026 10.1xFY2026
EPS, next fiscal year $2.85FY2026 $25.91FY2026 $5.07FY2026
EPS growth, next FY -11.5%FY2026 +13.3%FY2026 +7.9%FY2026
EPS growth, the year after -4.6% +2.0% +4.7%
Revenue, next fiscal year $60.59BFY2026 $50.12BFY2026 $48.12BFY2026
Revenue growth, next FY -3.2%FY2026 +12.5%FY2026 +7.8%FY2026
Revenue growth, the year after +3.9% -2.8% +1.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPFETMOGSK
Held by institutions 66.9% 90.2% 16.0%
Institutions holding 2,835 2,621 1,037
Change in shares held, QoQ +2.0% +0.8% -7.4%
Institutions buying 1,324 1,141 484
Institutions selling 1,204 1,144 334
Buyers to sellers 1.10 1.00 1.45

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PFETMOGSK
PFE 1.00 0.26 0.47
TMO 0.26 1.00 0.21
GSK 0.47 0.21 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, PFE, TMO and GSK?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Pfizer (PFE) $169.97B, Thermo Fisher Scientific (TMO) $257.69B, Gsk (GSK) $103.23B.

Which stock is cheaper, PFE, TMO and GSK?

Gsk (GSK) trades on the lowest price-to-earnings ratio (Pfizer (PFE) 39.2x, Thermo Fisher Scientific (TMO) 36.4x, Gsk (GSK) 7.8x). On next year's consensus earnings, Gsk (GSK) is cheapest (Pfizer (PFE) 10.5x, Thermo Fisher Scientific (TMO) 26.4x, Gsk (GSK) 10.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Gsk (GSK) grew revenue fastest over the trailing twelve months: Pfizer (PFE) -0.2%, Thermo Fisher Scientific (TMO) +8.3%, Gsk (GSK) +87.0%.

Which company is more profitable?

Gsk (GSK) has the highest net margin (Pfizer (PFE) 6.8%, Gsk (GSK) 17.3%).

Which stock has performed better?

Over the past year Pfizer (PFE) returned the most: Pfizer (PFE) +20.3%, Thermo Fisher Scientific (TMO) +19.6%, Gsk (GSK) +18.2%. Over five years, Gsk (GSK) compounded fastest (Pfizer (PFE) -7.1%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr, Gsk (GSK) +4.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Pfizer (PFE) 0.06%, Thermo Fisher Scientific (TMO) 0.00%, Gsk (GSK) 0.00%. Thermo Fisher Scientific (TMO) and Gsk (GSK) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Pfizer (PFE) 21.7%, Thermo Fisher Scientific (TMO) 29.9%, Gsk (GSK) 26.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PFE, TMO and GSK?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Gsk (GSK) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.