PFE vs TAK vs NVS Stock Comparison

Pfizer, Takeda Pharmaceutical and Novartis Ag Prices as of Oct 27, 2026 Peers: Industry group
PFE Pfizer Inc
$29.80 +3.9% 1M +20.3% 1Y
Market cap
$167.04B
P/E
38.6x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
5 wins
NVS Novartis Ag
$156.80 +7.8% 1M +21.4% 1Y
Market cap
$302.48B
P/E
17.9x
Revenue (TTM)
—
Div. yield
–
Pharmaceuticals Healthcare
3 wins

Head to Head

11 decided of 12

Pfizer leads on 5 of the 12 questions below (Pfizer 5, Novartis Ag 3, Takeda Pharmaceutical 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPFETAKNVSLeader
Larger companyMarket capitalisation $167.04B $63.40B $302.48B NVS
Cheaper on earningsLower P/E, profitable companies only 38.6x 110.4x 17.9x NVS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.5x 50.7x 16.9x PFE
Faster revenue growthRevenue growth, trailing twelve months -0.2% +0.7% — TAK
More profitableNet margin, trailing twelve months 6.8% 1.2% — PFE
Better return on capitalReturn on invested capital 13.4% 3.5% — PFE
Less leveragedLower net debt / EBITDA 1.9x 3.5x — PFE
Higher dividend yieldTrailing dividend yield 0.06% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +20.3% +43.2% +21.4% TAK
Better 5-year returnAnnualised price return, 5 years -7.2%/yr +7.5%/yr +13.5%/yr NVS
Less volatileAnnualised volatility, 1 year 21.6% 21.5% 27.9% TAK
Higher overall scoreMean of the five percentile scores vs peers 65/100 62/100 — PFE

Percentile Scorecard

PFETAKNVS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPFETAKNVS
Valuation 95 #35 of 625 97 #17 of 625 97 #20 of 625
Growth 24 #461 of 602 21 #478 of 602 –
Profitability 92 #45 of 551 85 #82 of 551 –
Financial Health 24 #502 of 656 34 #431 of 656 –
Shareholder Returns 91 #35 of 365 73 #98 of 365 81 #69 of 365
Overall 65 62 –
  • PFE ranked among 672 companies in Pharmaceuticals and Biotechnology
  • TAK ranked among 672 companies in Pharmaceuticals and Biotechnology
  • NVS ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPFETAKNVSSPY
1 month +3.9%+7.6%+7.8% -0.2%
3 months +18.0%+15.6%-1.9% +3.9%
6 months +12.5%+23.6%+7.8% +8.2%
Year to date +19.7%+30.1%+13.7% +12.9%
1 year +20.3%+43.2%+21.4% +12.3%
3 years -1.0%+50.6%+69.9% +87.4%
3 years, per year -0.3%+14.6%+19.3% +23.3%
5 years -31.0%+43.8%+88.2% +67.9%
5 years, per year -7.2%+7.5%+13.5% +10.9%
10 years -8.3%-10.9%+119.0% +261.1%
10 years, per year -0.9%-1.2%+8.2% +13.7%

Risk

MeasurePFETAKNVSSPY
Volatility, 1Y 21.6%21.5%27.9% 12.7%
Downside volatility, 1Y 21.1%20.2%30.7% 12.7%
Beta vs S&P 500, 1Y 0.230.110.34 1.00
Return / volatility, 1Y 0.942.010.77 0.97
Max drawdown, 5Y -64.8%-26.4%-20.4% -25.4%
From 52-week high -2.0%-0.7%-7.0% -1.2%
52-week high $30.41$20.43$168.62 $779.14
52-week low $23.67$13.23$121.80 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePFETAKNVS
P/E now vs peer median 39.2xmedian 17.2x 111.3xmedian 17.2x 17.9xmedian 17.2x
P/S now vs peer median 2.7xmedian 9.0x 1.4xmedian 9.0x 5.1xmedian 9.0x
EV/EBITDA now vs peer median 8.2xmedian 16.3x 12.4xmedian 16.3x —median 16.3x
P/FCF now vs peer median 15.5xmedian 18.7x 12.4xmedian 18.7x 14.3xmedian 18.7x
P/B now vs peer median 2.0xmedian 2.2x 1.4xmedian 2.2x —median 2.2x
PEG now vs peer median -0.95median 0.33 -2.74median 0.33 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPFETAKNVS
Revenue $63.70B $46.49B –
Gross profit $46.61B $30.58B –
Operating income $20.39B $2.71B –
Net income $4.36B -$1.04B –
Free cash flow $10.99B $5.20B –
R&D $11.05B $4.53B –
EPS (diluted) $0.76 $0.18 –
Cash & equivalents $976.00M $2.85B $400.00M
Total debt $63.19B $126.30B –
Shares (diluted) 5.70B 3.15B 1.96B
Enterprise value $113.68B $39.76B $275.72B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPFETAKNVS
P/E 39.2x 111.3x 17.9x
P/FCF 15.5x 12.4x 14.3x
P/Operating cash flow 12.7x 10.3x –
P/S 2.7x 1.4x 5.1x
P/B 2.0x 1.4x –
P/Tangible book 4.4x 2.5x –
EV/EBITDA 8.2x 12.4x –
EV/EBIT 10.9x 33.2x –
EV/Revenue 3.5x 1.9x –
EV/FCF 20.1x 17.3x –
EV/Operating cash flow 16.5x 14.3x –
PEG (3Y EPS CAGR) -0.95 -2.74 –

Growth

14 metrics
MetricPFETAKNVS
Revenue growth (1Y) -0.2% 0.7% –
Revenue CAGR (3Y) -7.0% 14.8% –
Gross profit growth (1Y) 1.2% -0.8% –
Gross profit CAGR (3Y) -5.6% -0.2% –
Operating income growth (1Y) 1.5% -43.4% –
Operating income CAGR (3Y) -9.9% -14.3% –
Net income growth (1Y) -59.6% -209.1% –
Net income CAGR (3Y) -41.3% -35.3% –
EPS growth (1Y) -59.7% -75.7% –
EPS CAGR (3Y) -41.3% -40.6% –
Operating cash flow growth (1Y) -11.8% -14.8% –
Operating cash flow CAGR (3Y) -2.7% -4.4% –
Free cash flow growth (1Y) -11.7% -13.3% –
Free cash flow CAGR (3Y) 1.0% -5.2% –

Profitability

14 metrics
MetricPFETAKNVS
Gross margin 73.2% 65.8% –
EBITDA margin 42.4% 15.6% –
Operating margin 32.0% 5.8% –
Pretax margin 6.6% 2.6% –
Net margin 6.8% 1.2% –
FCF margin 17.2% 11.2% –
Operating cash flow margin 21.0% 13.5% –
Return on equity 5.0% 1.2% –
Return on assets 2.1% 0.6% –
Return on invested capital 13.4% 3.5% –
Return on capital employed 11.9% 3.0% –
Asset turnover 0.3x 0.5x –
Cash conversion (OCF / net income) 3.1x -6.0x –
Stock comp / revenue 1.5% 1.0% –

Financial Health

11 metrics
MetricPFETAKNVS
Debt / assets 31.4% 32.0% –
Debt / equity 0.7x 0.7x –
Net debt / EBITDA 1.9x 3.5x –
Debt / FCF 5.8x 6.0x –
Liabilities / assets 57.5% 51.7% –
Equity / assets 42.5% 48.3% –
Interest coverage – 0.8x –
Current ratio 1.3x 3.2x –
Quick ratio 0.7x 1.9x –
Cash ratio 0.4x 0.9x –
Altman Z-score 2.36 1.57 –

Shareholder Returns

7 metrics
MetricPFETAKNVS
Dividend yield 5.8% 1.5% 3.0%
Net buyback yield – 1.0% –
Shareholder yield 5.8% 2.5% 3.0%
Payout ratio (earnings) 224.5% – –
Payout ratio (FCF) 89.1% – –
Dividend growth (1Y) 1.5% – –
Dividend CAGR (3Y) 2.4% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPFETAKNVS
Forward P/E 10.5xFY2026 50.7xFY2026 16.9xFY2026
EPS, next fiscal year $2.85FY2026 $0.40FY2026 $9.26FY2026
EPS growth, next FY -11.5%FY2026 +5.3%FY2026 +3.1%FY2026
EPS growth, the year after -4.6% +62.5% +1.2%
Revenue, next fiscal year $60.59BFY2026 $28.27BFY2026 $53.95BFY2026
Revenue growth, next FY -3.2%FY2026 -0.8%FY2026 -1.1%FY2026
Revenue growth, the year after +3.9% +11.9% +19.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPFETAKNVS
Held by institutions 66.9% 3.3% 7.0%
Institutions holding 2,835 378 1,607
Change in shares held, QoQ +2.0% +6.2% -5.9%
Institutions buying 1,324 212 662
Institutions selling 1,204 98 560
Buyers to sellers 1.10 2.16 1.18

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PFETAKNVS
PFE 1.00 0.43 0.48
TAK 0.43 1.00 0.49
NVS 0.48 0.49 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, PFE, TAK and NVS?

Novartis Ag (NVS) is the largest by market capitalisation: Pfizer (PFE) $167.04B, Takeda Pharmaceutical (TAK) $63.40B, Novartis Ag (NVS) $302.48B.

Which stock is cheaper, PFE, TAK and NVS?

Novartis Ag (NVS) trades on the lowest price-to-earnings ratio (Pfizer (PFE) 38.6x, Takeda Pharmaceutical (TAK) 110.4x, Novartis Ag (NVS) 17.9x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Pfizer (PFE) 10.5x, Takeda Pharmaceutical (TAK) 50.7x, Novartis Ag (NVS) 16.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Takeda Pharmaceutical (TAK) grew revenue fastest over the trailing twelve months: Pfizer (PFE) -0.2%, Takeda Pharmaceutical (TAK) +0.7%.

Which company is more profitable?

Pfizer (PFE) has the highest net margin (Pfizer (PFE) 6.8%, Takeda Pharmaceutical (TAK) 1.2%). On return on invested capital, Pfizer (PFE) leads (Pfizer (PFE) 13.4%, Takeda Pharmaceutical (TAK) 3.5%).

Which stock has performed better?

Over the past year Takeda Pharmaceutical (TAK) returned the most: Pfizer (PFE) +20.3%, Takeda Pharmaceutical (TAK) +43.2%, Novartis Ag (NVS) +21.4%. Over five years, Novartis Ag (NVS) compounded fastest (Pfizer (PFE) -7.2%/yr, Takeda Pharmaceutical (TAK) +7.5%/yr, Novartis Ag (NVS) +13.5%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Pfizer (PFE) 0.06%, Takeda Pharmaceutical (TAK) 0.00%, Novartis Ag (NVS) 0.00%. Takeda Pharmaceutical (TAK) and Novartis Ag (NVS) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Takeda Pharmaceutical (TAK) has been the steadiest (Pfizer (PFE) 21.6%, Takeda Pharmaceutical (TAK) 21.5%, Novartis Ag (NVS) 27.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PFE, TAK and NVS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Pfizer (PFE) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.