PFE vs AZN vs LLY Stock Comparison

Pfizer, Astrazeneca and Eli Lilly Prices as of Oct 26, 2026 Peers: Industry group
PFE Pfizer Inc
$29.79 +3.9% 1M +20.3% 1Y
Market cap
$169.97B
P/E
39.2x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
2 wins
AZN Astrazeneca Plc
$172.00 +3.2% 1M +3.3% 1Y
Market cap
$263.55B
P/E
25.2x
Revenue (TTM)
$58.67B
Div. yield
–
Pharmaceuticals Healthcare
1 win
LLY ELI LILLY & Co
$1,279.44 +8.0% 1M +55.0% 1Y
Market cap
$1.15T
P/E
42.9x
Revenue (TTM)
$79.67B
Div. yield
–
Pharmaceuticals Healthcare
8 wins

Head to Head

11 decided of 12

Eli Lilly leads on 8 of the 12 questions below (Eli Lilly 8, Pfizer 2, Astrazeneca 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionPFEAZNLLYLeader
Larger companyMarket capitalisation $169.97B $263.55B $1.15T LLY
Cheaper on earningsLower P/E, profitable companies only 39.2x 25.2x 42.9x AZN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 10.5x 17.2x 39.5x PFE
Faster revenue growthRevenue growth, trailing twelve months -0.2% +9.4% +49.6% LLY
More profitableNet margin, trailing twelve months 6.8% 17.8% 33.5% LLY
Better return on capitalReturn on invested capital 13.4% 23.3% 37.2% LLY
Less leveragedLower net debt / EBITDA 1.9x 1.4x 1.1x LLY
Higher dividend yieldTrailing dividend yield 0.06% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +20.3% +3.3% +55.0% LLY
Better 5-year returnAnnualised price return, 5 years -7.1%/yr +6.8%/yr +38.6%/yr LLY
Less volatileAnnualised volatility, 1 year 21.7% 27.4% 34.9% PFE
Higher overall scoreMean of the five percentile scores vs peers 65/100 71/100 72/100 LLY

Percentile Scorecard

PFEAZNLLY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisPFEAZNLLY
Valuation 94 #37 of 626 85 #96 of 626 75 #158 of 626
Growth 23 #466 of 604 70 #185 of 604 98 #15 of 604
Profitability 92 #46 of 555 94 #35 of 555 98 #12 of 555
Financial Health 24 #502 of 658 36 #421 of 658 26 #486 of 658
Shareholder Returns 91 #35 of 368 70 #112 of 368 63 #138 of 368
Overall 65 71 72
  • PFE ranked among 673 companies in Pharmaceuticals and Biotechnology
  • AZN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • LLY ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodPFEAZNLLYSPY
1 month +3.9%+3.2%+8.0% -0.8%
3 months +20.8%+1.4%+6.8% +3.5%
6 months +11.2%-8.3%+47.4% +7.0%
Year to date +19.6%-6.5%+19.1% +12.2%
1 year +20.3%+3.3%+55.0% +13.0%
3 years -1.1%+39.0%+128.4% +86.3%
3 years, per year -0.4%+11.6%+31.7% +23.1%
5 years -30.7%+39.2%+411.4% +68.6%
5 years, per year -7.1%+6.8%+38.6% +11.0%
10 years -8.1%+190.6%+1,566.8% +258.0%
10 years, per year -0.8%+11.3%+32.5% +13.6%

Risk

MeasurePFEAZNLLYSPY
Volatility, 1Y 21.7%27.4%34.9% 12.7%
Downside volatility, 1Y 21.1%27.3%29.9% 12.7%
Beta vs S&P 500, 1Y 0.230.220.23 1.00
Return / volatility, 1Y 0.940.121.58 1.02
Max drawdown, 5Y -64.8%-27.9%-34.8% -25.4%
From 52-week high -2.0%-17.9%-2.1% -1.8%
52-week high $30.41$209.48$1,306.74 $779.14
52-week low $23.67$155.60$813.53 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultiplePFEAZNLLY
P/E now vs peer median 39.2xmedian 17.1x 25.5xmedian 17.1x 42.7xmedian 17.1x
P/S now vs peer median 2.7xmedian 8.8x 4.5xmedian 8.8x 15.1xmedian 8.8x
EV/EBITDA now vs peer median 8.2xmedian 17.1x 14.5xmedian 17.1x 31.0xmedian 17.1x
P/FCF now vs peer median 15.5xmedian 18.0x 25.0xmedian 18.0x 66.2xmedian 18.0x
P/B now vs peer median 2.0xmedian 2.1x 5.3xmedian 2.1x 35.6xmedian 2.1x
PEG now vs peer median -0.95median 0.31 1.33median 0.31 0.70median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsPFEAZNLLY
Revenue $63.70B $58.67B $79.67B
Gross profit $46.61B $50.25B $66.44B
Operating income $20.39B $13.97B $38.18B
Net income $4.36B $10.45B $26.71B
Free cash flow $10.99B $10.67B $18.19B
R&D $11.05B $15.07B $14.60B
EPS (diluted) $0.76 $6.69 $29.89
Cash & equivalents $976.00M $4.90B $8.95B
Total debt $63.19B $106.76B $54.91B
Shares (diluted) 5.70B 1.56B 893.70M
Enterprise value $116.62B $237.24B $1.11T

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricPFEAZNLLY
P/E 39.2x 25.5x 42.7x
P/FCF 15.5x 25.0x 66.2x
P/Operating cash flow 12.7x 19.5x 42.9x
P/S 2.7x 4.5x 15.1x
P/B 2.0x 5.3x 35.6x
P/Tangible book 4.4x 21.1x 76.4x
EV/EBITDA 8.2x 14.5x 31.0x
EV/EBIT 10.9x 21.0x 32.8x
EV/Revenue 3.5x 5.0x 15.7x
EV/FCF 20.1x 27.6x 68.7x
EV/Operating cash flow 16.5x 21.5x 44.5x
PEG (3Y EPS CAGR) -0.95 1.33 0.70

Growth

14 metrics
MetricPFEAZNLLY
Revenue growth (1Y) -0.2% 9.4% 49.6%
Revenue CAGR (3Y) -7.0% 10.6% 39.2%
Gross profit growth (1Y) 1.2% 9.3% 51.0%
Gross profit CAGR (3Y) -5.6% 13.1% 42.5%
Operating income growth (1Y) 1.5% 23.4% 73.7%
Operating income CAGR (3Y) -9.9% 23.9% 71.0%
Net income growth (1Y) -59.6% 25.9% 93.6%
Net income CAGR (3Y) -41.3% 19.2% 60.2%
EPS growth (1Y) -59.7% 26.0% 94.9%
EPS CAGR (3Y) -41.3% 19.2% 60.7%
Operating cash flow growth (1Y) -11.8% 2.3% 156.7%
Operating cash flow CAGR (3Y) -2.7% 13.7% 65.1%
Free cash flow growth (1Y) -11.7% -4.5% 272.4%
Free cash flow CAGR (3Y) 1.0% 8.5% 69.8%

Profitability

14 metrics
MetricPFEAZNLLY
Gross margin 73.2% 85.6% 83.4%
EBITDA margin 42.4% 34.6% 50.6%
Operating margin 32.0% 23.8% 47.9%
Pretax margin 6.6% 21.5% 42.2%
Net margin 6.8% 17.8% 33.5%
FCF margin 17.2% 18.2% 22.8%
Operating cash flow margin 21.0% 23.3% 35.3%
Return on equity 5.0% 21.4% 82.1%
Return on assets 2.1% 9.1% 20.6%
Return on invested capital 13.4% 23.3% 37.2%
Return on capital employed 11.9% 16.8% 46.7%
Asset turnover 0.3x 0.5x 0.6x
Cash conversion (OCF / net income) 3.1x 1.3x 1.1x
Stock comp / revenue 1.5% – 0.8%

Financial Health

11 metrics
MetricPFEAZNLLY
Debt / assets 31.4% 27.9% 38.6%
Debt / equity 0.7x 0.6x 1.6x
Net debt / EBITDA 1.9x 1.4x 1.1x
Debt / FCF 5.8x 3.0x 3.0x
Liabilities / assets 57.5% 56.5% 76.2%
Equity / assets 42.5% 43.5% 23.8%
Interest coverage – 15.9x –
Current ratio 1.3x 0.9x 1.4x
Quick ratio 0.7x 0.7x 0.7x
Cash ratio 0.4x 0.2x 0.2x
Altman Z-score 2.36 3.46 8.57

Shareholder Returns

7 metrics
MetricPFEAZNLLY
Dividend yield 5.8% 1.4% 0.5%
Net buyback yield – 0.0% 0.5%
Shareholder yield 5.8% 1.4% 1.0%
Payout ratio (earnings) 224.5% – –
Payout ratio (FCF) 89.1% – –
Dividend growth (1Y) 1.5% – –
Dividend CAGR (3Y) 2.4% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusPFEAZNLLY
Forward P/E 10.5xFY2026 17.2xFY2026 39.5xFY2026
EPS, next fiscal year $2.85FY2026 $10.00FY2026 $32.40FY2026
EPS growth, next FY -11.5%FY2026 +9.2%FY2026 +33.8%FY2026
EPS growth, the year after -4.6% +6.1% +42.2%
Revenue, next fiscal year $60.59BFY2026 $59.02BFY2026 $85.28BFY2026
Revenue growth, next FY -3.2%FY2026 +0.5%FY2026 +30.8%FY2026
Revenue growth, the year after +3.9% +8.0% +17.4%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersPFEAZNLLY
Held by institutions 66.9% 52.1% 83.7%
Institutions holding 2,835 1,496 4,625
Change in shares held, QoQ +2.0% +7.8% +1.5%
Institutions buying 1,324 808 2,629
Institutions selling 1,204 468 1,469
Buyers to sellers 1.10 1.73 1.79

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

PFEAZNLLY
PFE 1.00 0.42 0.44
AZN 0.42 1.00 0.45
LLY 0.44 0.45 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, PFE, AZN and LLY?

Eli Lilly (LLY) is the largest by market capitalisation: Pfizer (PFE) $169.97B, Astrazeneca (AZN) $263.55B, Eli Lilly (LLY) $1.15T.

Which stock is cheaper, PFE, AZN and LLY?

Astrazeneca (AZN) trades on the lowest price-to-earnings ratio (Pfizer (PFE) 39.2x, Astrazeneca (AZN) 25.2x, Eli Lilly (LLY) 42.9x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Pfizer (PFE) 10.5x, Astrazeneca (AZN) 17.2x, Eli Lilly (LLY) 39.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Eli Lilly (LLY) grew revenue fastest over the trailing twelve months: Pfizer (PFE) -0.2%, Astrazeneca (AZN) +9.4%, Eli Lilly (LLY) +49.6%.

Which company is more profitable?

Eli Lilly (LLY) has the highest net margin (Pfizer (PFE) 6.8%, Astrazeneca (AZN) 17.8%, Eli Lilly (LLY) 33.5%). On return on invested capital, Eli Lilly (LLY) leads (Pfizer (PFE) 13.4%, Astrazeneca (AZN) 23.3%, Eli Lilly (LLY) 37.2%).

Which stock has performed better?

Over the past year Eli Lilly (LLY) returned the most: Pfizer (PFE) +20.3%, Astrazeneca (AZN) +3.3%, Eli Lilly (LLY) +55.0%. Over five years, Eli Lilly (LLY) compounded fastest (Pfizer (PFE) -7.1%/yr, Astrazeneca (AZN) +6.8%/yr, Eli Lilly (LLY) +38.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Pfizer (PFE) 0.06%, Astrazeneca (AZN) 0.00%, Eli Lilly (LLY) 0.00%. Astrazeneca (AZN) and Eli Lilly (LLY) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Pfizer (PFE) 21.7%, Astrazeneca (AZN) 27.4%, Eli Lilly (LLY) 34.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, PFE, AZN and LLY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Eli Lilly (LLY) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.