NXTS vs AMGN vs VRTX Stock Comparison

Nexentis Technologies, Amgen and Vertex Pharmaceuticals Prices as of Oct 23, 2026 Peers: Industry group
AMGN Amgen Inc
$439.26 +8.2% 1M +50.0% 1Y
Market cap
$240.04B
P/E
27.5x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
4 wins

Head to Head

10 decided of 12

Vertex Pharmaceuticals leads on 5 of the 12 questions below (Vertex Pharmaceuticals 5, Amgen 4, Nexentis Technologies 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNXTSAMGNVRTXLeader
Larger companyMarket capitalisation $432.55K $240.04B $131.27B AMGN
Cheaper on earningsLower P/E, profitable companies only 0.0x 27.5x 29.8x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 20.1x 28.8x AMGN
Faster revenue growthRevenue growth, trailing twelve months — +9.1% +10.2% VRTX
More profitableNet margin, trailing twelve months — 23.0% 35.0% VRTX
Better return on capitalReturn on invested capital — 14.3% — –
Less leveragedLower net debt / EBITDA 1.6x 2.7x — NXTS
Higher dividend yieldTrailing dividend yield 0.00% 0.02% 0.00% –
Better 1-year returnPrice return, last 12 months -98.1% +50.0% +24.0% AMGN
Better 5-year returnAnnualised price return, 5 years -86.3%/yr +16.0%/yr +23.4%/yr VRTX
Less volatileAnnualised volatility, 1 year 168.8% 29.6% 29.0% VRTX
Higher overall scoreMean of the five percentile scores vs peers 32/100 66/100 76/100 VRTX

Percentile Scorecard

NXTSAMGNVRTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNXTSAMGNVRTX
Valuation – 85 #92 of 624 80 #128 of 624
Growth 13 #526 of 603 62 #231 of 603 60 #245 of 603
Profitability 40 #334 of 555 94 #32 of 555 95 #30 of 555
Financial Health 43 #373 of 657 22 #512 of 657 53 #307 of 657
Shareholder Returns – 68 #118 of 370 92 #29 of 370
Overall 32 66 76
  • NXTS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • VRTX ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNXTSAMGNVRTXSPY
1 month -63.7%+8.2%+1.5% -1.0%
3 months -70.6%+16.8%+9.8% +2.9%
6 months -89.4%+27.5%+21.8% +6.4%
Year to date -95.5%+34.2%+15.6% +11.4%
1 year -98.1%+50.0%+24.0% +13.1%
3 years -99.9%+59.1%+41.8% +79.4%
3 years, per year -90.0%+16.7%+12.4% +21.5%
5 years -100.0%+109.9%+185.5% +67.7%
5 years, per year -86.3%+16.0%+23.4% +10.9%
10 years -100.0%+177.1%+548.7% +255.2%
10 years, per year -66.8%+10.7%+20.6% +13.5%

Risk

MeasureNXTSAMGNVRTXSPY
Volatility, 1Y 168.8%29.6%29.0% 12.7%
Downside volatility, 1Y 152.8%27.6%25.6% 12.7%
Beta vs S&P 500, 1Y 2.240.440.49 1.00
Return / volatility, 1Y -0.581.690.83 1.03
Max drawdown, 5Y -100.0%-26.7%-29.1% -25.4%
From 52-week high -98.1%-1.8%-6.1% -2.5%
52-week high $28.63$447.28$557.96 $779.14
52-week low $0.53$291.16$409.47 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNXTSAMGNVRTX
P/E now vs peer median 0.0xmedian 17.2x 27.1xmedian 17.2x 30.2xmedian 17.2x
P/S now vs peer median —median 8.8x 6.2xmedian 8.8x 10.5xmedian 8.8x
EV/EBITDA now vs peer median 1.5xmedian 16.0x 17.4xmedian 16.0x 25.0xmedian 16.0x
P/FCF now vs peer median —median 17.8x 23.3xmedian 17.8x 35.0xmedian 17.8x
P/B now vs peer median 0.2xmedian 2.1x 20.3xmedian 2.1x 6.6xmedian 2.1x
PEG now vs peer median 0.00median 0.32 10.23median 0.32 2.98median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNXTSAMGNVRTX
Revenue – $38.10B $12.59B
Gross profit – $26.48B $10.82B
Operating income -$5.28M $11.43B $4.78B
Net income -$14.06M $8.74B $4.41B
Free cash flow – $10.18B $3.80B
R&D $532.00K $7.63B $3.91B
EPS (diluted) $-17.10 $16.07 $17.26
Cash & equivalents $7.62M $13.99B $6.14B
Total debt $3.22M $57.30B –
Shares (diluted) 816.14K 544.00M 255.20M
Enterprise value -$22.21M $195.44B $103.28B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNXTSAMGNVRTX
P/E 0.0x 27.1x 30.2x
P/FCF – 23.3x 35.0x
P/Operating cash flow – 19.0x 30.9x
P/S – 6.2x 10.5x
P/B 0.2x 20.3x 6.6x
P/Tangible book -0.2x -27.0x 6.7x
EV/EBITDA 1.5x 17.4x 25.0x
EV/EBIT 1.5x 24.6x 26.1x
EV/Revenue – 7.4x 9.9x
EV/FCF – 27.6x 32.9x
EV/Operating cash flow – 22.5x 29.1x
PEG (3Y EPS CAGR) 0.00 10.23 2.98

Growth

14 metrics
MetricNXTSAMGNVRTX
Revenue growth (1Y) – 9.1% 10.2%
Revenue CAGR (3Y) – 12.7% 9.8%
Gross profit growth (1Y) – 17.6% 10.1%
Gross profit CAGR (3Y) – 10.3% 9.0%
Operating income growth (1Y) -7.7% 39.5% 21.8%
Operating income CAGR (3Y) 3.0% 6.4% 6.4%
Net income growth (1Y) -48.2% 32.1% 21.1%
Net income CAGR (3Y) -35.8% 3.1% 9.4%
EPS growth (1Y) -567.8% 31.4% 22.9%
EPS CAGR (3Y) -45.2% 2.7% 10.1%
Operating cash flow growth (1Y) – 3.9% 11.6%
Operating cash flow CAGR (3Y) – 4.9% 1.8%
Free cash flow growth (1Y) – -4.1% 8.5%
Free cash flow CAGR (3Y) – 1.7% -0.7%

Profitability

14 metrics
MetricNXTSAMGNVRTX
Gross margin – 69.5% 86.0%
EBITDA margin – 42.2% 39.7%
Operating margin – 30.0% 38.0%
Pretax margin – 27.0% 41.9%
Net margin – 23.0% 35.0%
FCF margin – 26.7% 30.2%
Operating cash flow margin – 32.8% 34.1%
Return on equity -157.0% 83.8% 22.2%
Return on assets -71.9% 9.3% 16.3%
Return on invested capital – 14.3% –
Return on capital employed -31.5% 16.7% 20.8%
Asset turnover – 0.4x 0.5x
Cash conversion (OCF / net income) – 1.4x 1.0x
Stock comp / revenue – 1.3% 5.5%

Financial Health

11 metrics
MetricNXTSAMGNVRTX
Debt / assets 2.3% 59.9% –
Debt / equity 0.2x 4.9x –
Net debt / EBITDA 1.6x 2.7x –
Debt / FCF – 5.6x –
Liabilities / assets 89.8% 87.8% 26.2%
Equity / assets 10.2% 12.2% 73.8%
Interest coverage – 4.3x –
Current ratio 3.7x 1.4x 3.2x
Quick ratio 3.2x 0.9x 2.5x
Cash ratio 3.2x 0.5x 2.0x
Altman Z-score – 2.28 13.31

Shareholder Returns

7 metrics
MetricNXTSAMGNVRTX
Dividend yield – 2.3% –
Net buyback yield – – 1.4%
Shareholder yield – 2.3% 1.4%
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNXTSAMGNVRTX
Forward P/E – 20.1xFY2026 28.8xFY2026
EPS, next fiscal year – $21.80FY2026 $18.20FY2026
EPS growth, next FY – -0.2%FY2026 -1.1%FY2026
EPS growth, the year after – +7.3% +23.5%
Revenue, next fiscal year – $41.51BFY2026 $12.66BFY2026
Revenue growth, next FY – +12.9%FY2026 +5.8%FY2026
Revenue growth, the year after – +2.2% +18.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNXTSAMGNVRTX
Held by institutions – 82.7% 95.1%
Institutions holding – 3,159 1,745
Change in shares held, QoQ – +4.5% +3.9%
Institutions buying – 1,451 902
Institutions selling – 1,217 605
Buyers to sellers – 1.19 1.49

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NXTSAMGNVRTX
NXTS 1.00 0.02 0.06
AMGN 0.02 1.00 0.55
VRTX 0.06 0.55 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, NXTS, AMGN and VRTX?

Amgen (AMGN) is the largest by market capitalisation: Nexentis Technologies (NXTS) $432.55K, Amgen (AMGN) $240.04B, Vertex Pharmaceuticals (VRTX) $131.27B.

Which stock is cheaper, NXTS, AMGN and VRTX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Nexentis Technologies (NXTS) 0.0x, Amgen (AMGN) 27.5x, Vertex Pharmaceuticals (VRTX) 29.8x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Amgen (AMGN) 20.1x, Vertex Pharmaceuticals (VRTX) 28.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Vertex Pharmaceuticals (VRTX) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, Vertex Pharmaceuticals (VRTX) +10.2%.

Which company is more profitable?

Vertex Pharmaceuticals (VRTX) has the highest net margin (Amgen (AMGN) 23.0%, Vertex Pharmaceuticals (VRTX) 35.0%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Nexentis Technologies (NXTS) -98.1%, Amgen (AMGN) +50.0%, Vertex Pharmaceuticals (VRTX) +24.0%. Over five years, Vertex Pharmaceuticals (VRTX) compounded fastest (Nexentis Technologies (NXTS) -86.3%/yr, Amgen (AMGN) +16.0%/yr, Vertex Pharmaceuticals (VRTX) +23.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Nexentis Technologies (NXTS) 0.00%, Amgen (AMGN) 0.02%, Vertex Pharmaceuticals (VRTX) 0.00%. Nexentis Technologies (NXTS) and Vertex Pharmaceuticals (VRTX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Vertex Pharmaceuticals (VRTX) has been the steadiest (Nexentis Technologies (NXTS) 168.8%, Amgen (AMGN) 29.6%, Vertex Pharmaceuticals (VRTX) 29.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NXTS, AMGN and VRTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vertex Pharmaceuticals (VRTX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.