NTRA vs SHC vs BLLN Stock Comparison

Natera, Sotera Health and BillionToOne Prices as of Oct 28, 2026 Peers: Industry group
NTRA Natera, Inc.
$424.42 +3.1% 1M +123.9% 1Y
Market cap
$60.95B
P/E
–
Revenue (TTM)
$2.71B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
SHC Sotera Health Co
$18.65 +1.1% 1M +12.6% 1Y
Market cap
$5.32B
P/E
32.6x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
6 wins
BLLN BillionToOne, Inc.
$114.00 -6.3% 1M
Market cap
$5.34B
P/E
176.0x
Revenue (TTM)
$397.41M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

11 decided of 12

Sotera Health leads on 6 of the 12 questions below (Sotera Health 6, Natera 3, BillionToOne 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNTRASHCBLLNLeader
Larger companyMarket capitalisation $60.95B $5.32B $5.34B NTRA
Cheaper on earningsLower P/E, profitable companies only -316.1x 32.6x 176.0x SHC
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 20.3x 150.0x SHC
Faster revenue growthRevenue growth, trailing twelve months +37.8% +8.1% +90.1% BLLN
More profitableNet margin, trailing twelve months -7.1% 13.4% 7.6% SHC
Better return on capitalReturn on invested capital -11.7% 9.1% 7.0% SHC
Less leveragedLower net debt / EBITDA 4.5x 3.3x -9.1x BLLN
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +123.9% +12.6% — NTRA
Better 5-year returnAnnualised price return, 5 years +30.0%/yr -5.5%/yr — NTRA
Less volatileAnnualised volatility, 1 year 47.9% 28.4% 94.3% SHC
Higher overall scoreMean of the five percentile scores vs peers 51/100 59/100 57/100 SHC

Percentile Scorecard

NTRASHCBLLN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNTRASHCBLLN
Valuation 17 #77 of 92 52 #45 of 92 21 #73 of 92
Growth 71 #26 of 87 67 #29 of 87 100 #1 of 87
Profitability 32 #59 of 86 82 #16 of 86 61 #34 of 86
Financial Health 85 #15 of 97 35 #63 of 97 96 #5 of 97
Shareholder Returns 48 #29 of 55 – 7 #51 of 55
Overall 51 59 57
  • NTRA ranked among 102 companies in Healthcare Providers
  • SHC ranked among 102 companies in Healthcare Providers
  • BLLN ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNTRASHCBLLNSPY
1 month +3.1%+1.1%-6.3% +0.9%
3 months +67.2%+6.4%-14.0% +5.9%
6 months +117.9%+20.7%+54.7% +8.5%
Year to date +85.3%+5.7%+39.3% +13.3%
1 year +123.9%+12.6%— +12.4%
3 years +1,009.3%+49.1%— +88.1%
3 years, per year +123.1%+14.2%— +23.5%
5 years +270.4%-24.5%— +68.2%
5 years, per year +30.0%-5.5%— +11.0%
10 years +4,887.3%—— +263.4%
10 years, per year +47.8%—— +13.8%

Risk

MeasureNTRASHCBLLNSPY
Volatility, 1Y 47.9%28.4%94.3% 12.7%
Downside volatility, 1Y 44.6%27.1%107.3% 12.7%
Beta vs S&P 500, 1Y 1.241.011.66 1.00
Return / volatility, 1Y 2.590.44— 0.98
Max drawdown, 5Y -76.4%-78.2%-50.8% -25.4%
From 52-week high -0.3%-4.7%-24.0% -0.9%
52-week high $425.64$19.57$149.97 $779.14
52-week low $182.65$13.13$64.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNTRASHCBLLN
P/E now vs peer median -316.1xmedian 25.6x 32.6xmedian 25.6x 176.0xmedian 25.6x
P/S now vs peer median 22.5xmedian 1.6x 4.4xmedian 1.6x 13.4xmedian 1.6x
EV/EBITDA now vs peer median -267.3xmedian 16.3x 13.1xmedian 16.3x 97.1xmedian 16.3x
P/FCF now vs peer median 723.9xmedian 21.3x 47.2xmedian 21.3x 160.9xmedian 21.3x
P/B now vs peer median 33.5xmedian 3.3x 8.0xmedian 3.3x 9.9xmedian 3.3x
PEG now vs peer median -9.52median 0.68 0.87median 0.68 —median 0.68

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNTRASHCBLLN
Revenue $2.71B $1.22B $397.41M
Gross profit $1.71B $668.51M $283.22M
Operating income -$289.67M $411.34M $43.30M
Net income -$192.36M $163.48M $37.71M
Free cash flow $84.20M $112.70M $33.18M
R&D $787.38M – $59.21M
EPS (diluted) $-1.34 $0.57 $0.55
Cash & equivalents $1.10B $356.72M $548.63M
Total debt $80.29M $2.14B $91.03M
Shares (diluted) 143.28M 288.15M 54.46M
Enterprise value $56.63B $4.01B $3.56B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNTRASHCBLLN
P/E -316.1x 32.6x 176.0x
P/FCF 723.9x 47.2x 160.9x
P/Operating cash flow 267.1x 18.2x 117.7x
P/S 22.5x 4.4x 13.4x
P/B 33.5x 8.0x 9.9x
P/Tangible book 41.7x 13.5x 9.9x
EV/EBITDA -267.3x 13.1x 97.1x
EV/EBIT -206.9x 17.3x 112.7x
EV/Revenue 22.1x 5.8x 12.3x
EV/FCF 711.8x 63.0x 147.1x
EV/Operating cash flow 262.6x 24.3x 107.6x
PEG (3Y EPS CAGR) -9.52 0.87 –

Growth

14 metrics
MetricNTRASHCBLLN
Revenue growth (1Y) 37.8% 8.1% 90.1%
Revenue CAGR (3Y) 42.7% 7.6% –
Gross profit growth (1Y) 43.6% 7.1% 122.4%
Gross profit CAGR (3Y) 68.1% 8.1% –
Operating income growth (1Y) 1.3% 21.8% 253.2%
Operating income CAGR (3Y) 17.3% 23.2% –
Net income growth (1Y) 24.0% 580.5% 223.2%
Net income CAGR (3Y) 27.8% 37.7% –
EPS growth (1Y) 27.7% 574.9% 118.7%
EPS CAGR (3Y) 33.2% 37.5% –
Operating cash flow growth (1Y) 22.2% 9.8% –
Operating cash flow CAGR (3Y) 38.6% 61.3% –
Free cash flow growth (1Y) -26.8% 0.0% –
Free cash flow CAGR (3Y) 30.4% 32.6% –

Profitability

14 metrics
MetricNTRASHCBLLN
Gross margin 63.2% 55.0% 71.3%
EBITDA margin -8.3% 44.6% 12.6%
Operating margin -10.7% 33.8% 10.9%
Pretax margin -9.3% 21.7% 9.5%
Net margin -7.1% 13.4% 7.6%
FCF margin 3.1% 9.3% 8.3%
Operating cash flow margin 8.4% 24.0% 11.4%
Return on equity -10.7% 25.4% 7.2%
Return on assets -7.3% 5.0% 5.3%
Return on invested capital -11.7% 9.1% 7.0%
Return on capital employed -13.9% 13.5% 6.6%
Asset turnover 1.0x 0.4x 0.6x
Cash conversion (OCF / net income) -1.2x 1.8x 1.2x
Stock comp / revenue 14.1% 3.1% 6.4%

Financial Health

11 metrics
MetricNTRASHCBLLN
Debt / assets 3.0% 64.7% 12.5%
Debt / equity 0.0x 3.2x 0.2x
Net debt / EBITDA 4.5x 3.3x -9.1x
Debt / FCF 1.0x 19.0x 2.7x
Liabilities / assets 31.5% 79.9% 26.4%
Equity / assets 68.5% 20.1% 73.6%
Interest coverage -75.9x – 1,056x
Current ratio 3.0x 2.8x 11.7x
Quick ratio 2.8x 2.4x 11.2x
Cash ratio 2.0x 1.5x 9.8x
Altman Z-score 43.36 1.95 17.85

Shareholder Returns

7 metrics
MetricNTRASHCBLLN
Dividend yield – – –
Net buyback yield -0.1% – -5.7%
Shareholder yield -0.1% – -5.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNTRASHCBLLN
Forward P/E – 20.3xFY2026 150.0xFY2026
EPS, next fiscal year $-1.48FY2026 $0.92FY2026 $0.76FY2026
EPS growth, next FY – +7.0%FY2026 +442.9%FY2026
EPS growth, the year after – +21.7% +22.4%
Revenue, next fiscal year $3.07BFY2026 $1.33BFY2026 $481.76MFY2026
Revenue growth, next FY +32.8%FY2026 +14.8%FY2026 +57.9%FY2026
Revenue growth, the year after +7.2% -4.2% +27.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNTRASHCBLLN
Held by institutions 95.5% 100.0% 36.1%
Institutions holding 847 316 155
Change in shares held, QoQ +2.7% +5.9% +34.7%
Institutions buying 513 220 127
Institutions selling 240 64 13
Buyers to sellers 2.14 3.44 9.77

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NTRASHCBLLN
NTRA 1.00 0.36 0.35
SHC 0.36 1.00 0.14
BLLN 0.35 0.14 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, NTRA, SHC and BLLN?

Natera (NTRA) is the largest by market capitalisation: Natera (NTRA) $60.95B, Sotera Health (SHC) $5.32B, BillionToOne (BLLN) $5.34B.

Which stock is cheaper, NTRA, SHC and BLLN?

Sotera Health (SHC) trades on the lowest price-to-earnings ratio (Natera (NTRA) -316.1x, Sotera Health (SHC) 32.6x, BillionToOne (BLLN) 176.0x). On next year's consensus earnings, Sotera Health (SHC) is cheapest (Sotera Health (SHC) 20.3x, BillionToOne (BLLN) 150.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: Natera (NTRA) +37.8%, Sotera Health (SHC) +8.1%, BillionToOne (BLLN) +90.1%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Natera (NTRA) -7.1%, Sotera Health (SHC) 13.4%, BillionToOne (BLLN) 7.6%). On return on invested capital, Sotera Health (SHC) leads (Natera (NTRA) -11.7%, Sotera Health (SHC) 9.1%, BillionToOne (BLLN) 7.0%).

Which stock has performed better?

Over the past year Natera (NTRA) returned the most: Natera (NTRA) +123.9%, Sotera Health (SHC) +12.6%. Over five years, Natera (NTRA) compounded fastest (Natera (NTRA) +30.0%/yr, Sotera Health (SHC) -5.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Natera (NTRA) 47.9%, Sotera Health (SHC) 28.4%, BillionToOne (BLLN) 94.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NTRA, SHC and BLLN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Sotera Health (SHC) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.