NEO vs GH vs SHC Stock Comparison

Neogenomics, Guardant Health and Sotera Health Prices as of Oct 27, 2026 Peers: Industry group
NEO Neogenomics Inc
$17.27 -10.7% 1M +70.0% 1Y
Market cap
$2.21B
P/E
–
Revenue (TTM)
$766.30M
Div. yield
–
Diagnostic Labs Healthcare
GH Guardant Health, Inc.
$178.06 +0.5% 1M +151.3% 1Y
Market cap
$23.79B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
4 wins
SHC Sotera Health Co
$18.49 +0.8% 1M +10.7% 1Y
Market cap
$5.28B
P/E
32.3x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
4 wins

Head to Head

8 decided of 12

Guardant Health leads on 4 of the 12 questions below (Guardant Health 4, Sotera Health 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNEOGHSHCLeader
Larger companyMarket capitalisation $2.21B $23.79B $5.28B GH
Cheaper on earningsLower P/E, profitable companies only -43.2x -52.2x 32.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 86.4x — 20.1x SHC
Faster revenue growthRevenue growth, trailing twelve months +11.2% +42.7% +8.1% GH
More profitableNet margin, trailing twelve months -6.8% -38.3% 13.4% SHC
Better return on capitalReturn on invested capital — — 9.1% –
Less leveragedLower net debt / EBITDA — — 3.3x –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +70.0% +151.3% +10.7% GH
Better 5-year returnAnnualised price return, 5 years -17.8%/yr +8.5%/yr -5.8%/yr GH
Less volatileAnnualised volatility, 1 year 53.8% 57.4% 28.4% SHC
Higher overall scoreMean of the five percentile scores vs peers 50/100 28/100 59/100 SHC

Percentile Scorecard

NEOGHSHC

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNEOGHSHC
Valuation 32 #63 of 92 18 #76 of 92 52 #45 of 92
Growth 67 #29 of 87 49 #45 of 87 66 #30 of 87
Profitability 32 #59 of 86 7 #80 of 86 82 #16 of 86
Financial Health 71 #29 of 97 52 #47 of 97 37 #62 of 97
Shareholder Returns 49 #29 of 56 15 #48 of 56 –
Overall 50 28 59
  • NEO ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers
  • SHC ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNEOGHSHCSPY
1 month -10.7%+0.5%+0.8% -0.2%
3 months +28.9%+24.0%+4.1% +3.9%
6 months +91.5%+114.3%+19.0% +8.2%
Year to date +46.9%+74.3%+4.8% +12.9%
1 year +70.0%+151.3%+10.7% +12.3%
3 years +26.9%+613.4%+47.8% +87.4%
3 years, per year +8.3%+92.6%+13.9% +23.3%
5 years -62.5%+50.7%-25.6% +67.9%
5 years, per year -17.8%+8.5%-5.8% +10.9%
10 years +111.4%—— +261.1%
10 years, per year +7.8%—— +13.7%

Risk

MeasureNEOGHSHCSPY
Volatility, 1Y 53.8%57.4%28.4% 12.7%
Downside volatility, 1Y 53.3%48.7%27.0% 12.7%
Beta vs S&P 500, 1Y 1.061.031.01 1.00
Return / volatility, 1Y 1.302.640.38 0.97
Max drawdown, 5Y -89.7%-86.7%-78.2% -25.4%
From 52-week high -13.3%-4.9%-5.5% -1.2%
52-week high $19.91$187.22$19.57 $779.14
52-week low $7.19$69.58$13.13 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNEOGHSHC
P/E now vs peer median -43.2xmedian 24.6x -52.2xmedian 24.6x 32.3xmedian 24.6x
P/S now vs peer median 2.9xmedian 1.6x 20.1xmedian 1.6x 4.3xmedian 1.6x
EV/EBITDA now vs peer median -921.7xmedian 14.6x -52.7xmedian 14.6x 13.0xmedian 14.6x
P/FCF now vs peer median -300.4xmedian 21.6x -98.8xmedian 21.6x 46.8xmedian 21.6x
P/B now vs peer median 2.8xmedian 3.2x -106.8xmedian 3.2x 7.9xmedian 3.2x
PEG now vs peer median -1.77median 0.66 -5.25median 0.66 0.86median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNEOGHSHC
Revenue $766.30M $1.18B $1.22B
Gross profit $336.53M $769.16M $668.51M
Operating income -$68.44M -$470.26M $411.34M
Net income -$51.88M -$453.44M $163.48M
Free cash flow -$7.36M -$240.72M $112.70M
R&D $38.17M $375.79M –
EPS (diluted) $-0.40 $-3.41 $0.57
Cash & equivalents $145.54M $1.05B $356.72M
Total debt – – $2.14B
Shares (diluted) 130.83M 132.87M 288.15M
Enterprise value $1.59B $19.85B $3.96B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNEOGHSHC
P/E -43.2x -52.2x 32.3x
P/FCF -300.4x -98.8x 46.8x
P/Operating cash flow 100.2x -128.5x 18.1x
P/S 2.9x 20.1x 4.3x
P/B 2.8x -106.8x 7.9x
P/Tangible book 4.3x -95.9x 13.3x
EV/EBITDA -921.7x -52.7x 13.0x
EV/EBIT -30.2x -48.4x 17.2x
EV/Revenue 2.7x 19.2x 5.8x
EV/FCF -280.6x -94.5x 62.6x
EV/Operating cash flow 93.6x -122.8x 24.2x
PEG (3Y EPS CAGR) -1.77 -5.25 0.86

Growth

14 metrics
MetricNEOGHSHC
Revenue growth (1Y) 11.2% 42.7% 8.1%
Revenue CAGR (3Y) 11.6% 32.4% 7.6%
Gross profit growth (1Y) 11.2% 47.7% 7.1%
Gross profit CAGR (3Y) 15.1% – 8.1%
Operating income growth (1Y) 40.5% -2.1% 21.8%
Operating income CAGR (3Y) 19.4% 4.8% 23.2%
Net income growth (1Y) 50.1% -9.6% 580.5%
Net income CAGR (3Y) 23.2% 3.7% 37.7%
EPS growth (1Y) 51.2% -2.4% 574.9%
EPS CAGR (3Y) 24.3% 9.9% 37.5%
Operating cash flow growth (1Y) 56.9% 22.4% 9.8%
Operating cash flow CAGR (3Y) 38.3% 18.1% 61.3%
Free cash flow growth (1Y) 61.6% 11.4% 0.0%
Free cash flow CAGR (3Y) 51.4% 14.4% 32.6%

Profitability

14 metrics
MetricNEOGHSHC
Gross margin 43.9% 65.0% 55.0%
EBITDA margin -0.3% -36.5% 44.6%
Operating margin -8.9% -39.7% 33.8%
Pretax margin -7.1% -38.4% 21.7%
Net margin -6.8% -38.3% 13.4%
FCF margin -1.0% -20.3% 9.3%
Operating cash flow margin 2.9% -15.7% 24.0%
Return on equity -6.4% – 25.4%
Return on assets -3.8% -23.7% 5.0%
Return on invested capital – – 9.1%
Return on capital employed -5.5% -29.9% 13.5%
Asset turnover 0.6x 0.6x 0.4x
Cash conversion (OCF / net income) -0.4x 0.4x 1.8x
Stock comp / revenue 4.7% 16.2% 3.1%

Financial Health

11 metrics
MetricNEOGHSHC
Debt / assets – – 64.7%
Debt / equity – – 3.2x
Net debt / EBITDA – – 3.3x
Debt / FCF – – 19.0x
Liabilities / assets 41.9% 111.7% 79.9%
Equity / assets 58.1% -11.7% 20.1%
Interest coverage -26.5x -97.6x –
Current ratio 3.6x 4.0x 2.8x
Quick ratio 3.0x 3.5x 2.4x
Cash ratio 1.4x 3.1x 1.5x
Altman Z-score 2.52 4.77 1.94

Shareholder Returns

7 metrics
MetricNEOGHSHC
Dividend yield – – –
Net buyback yield -0.1% -1.7% –
Shareholder yield -0.1% -1.7% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNEOGHSHC
Forward P/E 86.4xFY2026 – 20.1xFY2026
EPS, next fiscal year $0.20FY2026 $-3.33FY2026 $0.92FY2026
EPS growth, next FY +66.7%FY2026 – +7.0%FY2026
EPS growth, the year after +80.0% – +21.7%
Revenue, next fiscal year $778.61MFY2026 $1.42BFY2026 $1.33BFY2026
Revenue growth, next FY +7.1%FY2026 +44.5%FY2026 +14.8%FY2026
Revenue growth, the year after +6.5% +27.0% -4.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNEOGHSHC
Held by institutions 100.0% 100.0% 100.0%
Institutions holding 266 594 316
Change in shares held, QoQ +8.1% -2.6% +5.9%
Institutions buying 156 353 220
Institutions selling 62 180 64
Buyers to sellers 2.52 1.96 3.44

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NEOGHSHC
NEO 1.00 0.38 0.44
GH 0.38 1.00 0.28
SHC 0.44 0.28 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, NEO, GH and SHC?

Guardant Health (GH) is the largest by market capitalisation: Neogenomics (NEO) $2.21B, Guardant Health (GH) $23.79B, Sotera Health (SHC) $5.28B.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Neogenomics (NEO) +11.2%, Guardant Health (GH) +42.7%, Sotera Health (SHC) +8.1%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Neogenomics (NEO) -6.8%, Guardant Health (GH) -38.3%, Sotera Health (SHC) 13.4%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Neogenomics (NEO) +70.0%, Guardant Health (GH) +151.3%, Sotera Health (SHC) +10.7%. Over five years, Guardant Health (GH) compounded fastest (Neogenomics (NEO) -17.8%/yr, Guardant Health (GH) +8.5%/yr, Sotera Health (SHC) -5.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Neogenomics (NEO) 53.8%, Guardant Health (GH) 57.4%, Sotera Health (SHC) 28.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NEO, GH and SHC?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.